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Dextromethorphan found to have potential in treating lung fibrosis

A common over-the-counter ingredient in many cough syrups may have a greater purpose for people suffering from lung fibrosis that is related to any number of serious health conditions.

22 Dec 2024

Simple device could be a gamechanger for asthma patients

A device costing just pennies, based on an idea by a University of Manchester Professor to help his son use an inhaler, could be a gamechanger for asthma patients.

22 Dec 2024

Unexpected discovery opens doors for improved siRNA therapies

In everyday life, when things turn out the opposite of what you expect, it's usually cause for frustration. In science, it's often the starting point for discovery.

20 Dec 2024

New insights into respiratory syncytial virus and prevention strategies

Respiratory syncytial virus (RSV) is a major cause of respiratory infections, particularly in infants, children under 5 years, and older adults. Its rapid spread makes RSV a serious public health concern. Currently, there are no effective medications for RSV, and current treatment focuses on providing supportive care and preventing its spread.

20 Dec 2024

Comprehensive study highlights effectiveness and limitations of ADHD treatments in adults

Findings indicate stimulants and atomoxetine effectively reduce ADHD symptoms, though non-pharmacological therapies show potential for long-term efficacy.

20 Dec 2024

Insights into LKB1's role in tumorigenesis

A new publication from Genes & Diseases; DOI 10.1016/j.gendis.2024.101402, discusses insights into targeting LKB1 in tumorigenesis.

20 Dec 2024

Adding SBRT to sorafenib improves survival in hepatocellular carcinoma patients

Recent results from the Phase III NRG-RTOG 1112 clinical study showed that the addition of stereotactic body radiotherapy (SBRT) to systemic therapy with sorafenib significantly improved progression-free survival (PFS) and time-to-progression in patients with locally advanced hepatocellular carcinoma (HCC) when compared to sorafenib alone.

20 Dec 2024

Review highlights gaps in reporting quality of nonpharmacological treatments in Chinese medicine

Nonpharmacological treatments in Chinese medicine (NPTCM), including acupuncture, cupping, moxibustion, and Tuina, have gained global recognition for their efficacy in various health conditions.

20 Dec 2024

A scaffolded vaccine approach for broader influenza protection

Most people who get the seasonal influenza vaccine – which contains strains of viruses from distinct virus subtypes – mount a strong immune response to one strain, leaving them vulnerable to infection by the others, and researchers have long wondered what impacts such variable responses more – host genetics or prior exposure to virus strains.

19 Dec 2024

Nogo-A inhibition demonstrates potential for spinal cord injury recovery

The latest study results have been published online in the renowned "The Lancet Neurology" journal. A multi-centre clinical trial (NISCI trial: Nogo-A Inhibition in acute Spinal Cord Injury Study) investigated the antibody NG 101 (anti-Nogo-A), which blocks and thus neutralizes the body's own Nogo-A protein.

19 Dec 2024

Vanderbilt researchers achieve milestone in Alzheimer's drug development

Researchers at the Warren Center for Neuroscience Drug Discovery, a clinical stage biotech within the Vanderbilt University School of Medicine Basic Sciences, have detailed the successful drug discovery of a phase I single ascending dose clinical trial of VU319, a drug for memory loss in people with Alzheimer's disease and schizophrenia.

19 Dec 2024

New design could make seasonal influenza vaccinations more broadly effective

Stanford Medicine scientists have designed a way to make our seasonal influenza vaccinations more broadly effective and possibly to protect us from new flu variants with pandemic potential.

19 Dec 2024

Sunscreen prototype keeps skin cooler and shields from UV rays

Wearing sunscreen is important to protect your skin from the harmful effects of UV radiation but doesn't cool people off.

19 Dec 2024

AHCC supplement shows potential in protecting the liver from fibrosis

Chronic liver damage can lead to hepatitis, which causes fibrosis of the liver. This buildup of collagen and other fibrous tissue accelerates when hepatic stellate cells become activated during hepatitis, often resulting in liver cancer or cirrhosis, both of which can be fatal.

19 Dec 2024

Breakthrough in antigen recognition: TRACeR-I enhances immune targeting

Researchers describe TRACeR-I, a protein platform that can be used to engineer immune responses.

19 Dec 2024

Can probiotics restore antibiotic-perturbed microbiota?

Probiotics can reduce antibiotic-associated diarrhea but don't fully restore gut microbiota. Further studies are essential to evaluate their long-term effects.

19 Dec 2024

Chemogenetic activation reveals male-female differences in stress resistance neural circuits

Subtle activation of a small subset of neurons in one region of the brain can make male mice resilient to, and even reverse, the detrimental effects of chronic stress. The same is true for female mice, but in a totally different region of the brain.

19 Dec 2024

Surgeons slow to adopt new biomaterials for bone defects

Two million bone transplants are performed worldwide yearly, including half a million in the United States alone. Yet, a QUT-led study has found surgeons are slow to adopt newly developed biomaterials or tissue-engineered solutions.

19 Dec 2024

Cough syrup ingredient may help combat lung fibrosis

A common over-the-counter ingredient in many cough syrups may have a greater purpose for people suffering from lung fibrosis that is related to any number of serious health conditions.

18 Dec 2024

New approach in fighting leukemia with double-modified natural killer cells

Various forms of blood cancer exist – all of which are grouped together under the term leukemia. One common form of leukemia is acute myeloid leukemia (AML), characterized by a degradation of early blood cell precursors, i.e. stem cells and the precursor cells that develop from them.

18 Dec 2024