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Heart-healthy forager-farmers in Bolivia are experiencing changes in body mass and diet

A group of forager-farmers in Bolivia's tropical forests -- known for having remarkable cardiovascular health and low blood pressure -- experienced changes in body mass and diet over a nine-year period, with increased use of cooking oil the most notable dietary change.

16 Sep 2019

Drugs used to treat retinal diseases are excreted into human breast milk, study finds

Certain drugs used to treat retinal diseases are excreted into breast milk, raising possible safety concerns for developing infants, suggests a first-of-its-kind study led by St. Michael's Hospital in Toronto and published in Ophthalmology.

15 Sep 2019

Study shows how the immune system achieves antibody diversity

Diversity is good, especially when it comes to antibodies. It's long been known that a gene assembly process called V(D)J recombination allows our immune system to mix and match bits of genetic code, generating new antibodies to conquer newly encountered threats.

15 Sep 2019

Fight or flight response may originate in our bones

A new study suggests that the main coordinator of the body’s fight-or-flight response is a hormone called osteocalcin, which is secreted by bone.

13 Sep 2019

CRISPR may explain why so many experimental cancer drugs fail

Scientists have used CRISPR–Cas9 to investigate how ten cancer drugs interact with their protein target, revealing some intriguing findings.

13 Sep 2019

Bone marrow cells contribute to pregnancy success in mouse model

Scientists report that stem cells derived from the adult bone marrow can dictate whether a woman becomes pregnant.

13 Sep 2019

Failed cancer drug could potentially be used to treat fibrotic diseases and scleroderma

Sixteen years ago, a research group at Mayo Medical School published results showing that a protein called TRAIL can kill cells that cause liver fibrosis but no one seemed to follow up on these findings.

From Johns Hopkins Medicine 13 Sep 2019

Discovery opens up new opportunities to understand the genetics of cancer

University of Delaware molecular biologist Mona Batish and collaborators at Harvard Medical School and University of California, Los Angeles, have identified a new circular ribonucleic acid (RNA) that increases tumor activity in soft tissue and connective tissue tumors.

13 Sep 2019

Plant-based diet could heal your rheumatoid arthritis

According to the latest review, adopting a plant-based diet could well relieve the swollen joints and pain of rheumatoid arthritis (RA).

13 Sep 2019

Protein messengers from human microbiome shed light on human health

The human body has been studied for centuries, but there are still mysteries that are yet to unfold. For instance, it was discovered that there are trillions of bacteria living inside the body, those that are beneficial for health. Now, studies are focused on studying the human microbiome and how they affect health and well-being.

12 Sep 2019

Scientists discover new drug target for fatal lung condition

Scientists have identified a molecular pathway that contributes to the development of pulmonary arterial hypertension, a severe, often fatal condition that has no cure.

12 Sep 2019

Scientists use CAR-T cells to reverse cardiac fibrosis

Scientists have used CAR-T cell therapy to treat cardiac fibrosis, a key part of heart disease and cardiac arrest.

12 Sep 2019

Researchers explore remodeling of cardiac tissues post-aortic valve replacement

University of Colorado Boulder engineers and faculty from the Consortium for Fibrosis Research & Translation at the University of Colorado Anschutz Medical Campus have teamed up to develop biomaterial-based "mimics" of heart tissues to measure patients' responses to an aortic valve replacement procedure, offering new insight into the ways that cardiac tissue re-shapes itself post-surgery.

12 Sep 2019

BIA Separations launches Cornerstone AAV Process Development Service to improve gene therapy production

BIA Separations, a leading bio-chromatography development and manufacturing company, today announced the introduction of CORNERSTONE AAV Process Development Service, a program of integrated process development services and novel technology designed to improve the robustness and yield of AAV-based gene therapy production, while improving the safety of therapeutic products.

12 Sep 2019

Accelerating Nanobody Production using Polyclonal Anti-VHH Antibodies

In this interview, Dr. Dave Fancy, CEO of Jackson ImmunoResearch explains how anti-VHH antibodies can be used to produce nanobodies and VHH libraries.

From Jackson ImmunoResearch Laboratories, Inc. 12 Sep 2019

Malarial treatment from Antarctic sea sponge

Malaria, which ravages hot tropical areas, could be treated effectively using a protein extracted from an Antarctic sponge.

12 Sep 2019

New insight into origin of diabetes in overweight patients

In Switzerland, more than 400,000 people suffer from type 2 diabetes, a serious metabolic disorder that is constantly increasing. Obesity, by promoting the resistance to the action of insulin - one of the hormones that regulate blood sugar levels - is a major risk factor.

12 Sep 2019