Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

UA researchers receive $4.4 million grant to focus on idiopathic pulmonary fibrosis

Scar tissue is a good thing. When you fall and scrape your knee, the natural process jumps into gear, sealing up wounds and healing damaged tissue.

6 Sep 2018

Novel approaches for personalized risk prognosis and individualized treatment of NAFLD

More and more adults - but also about 34 percent of obese children - suffer from non-alcoholic fatty liver disease. An unhealthy lifestyle with little physical activity and a diet high in fat, sugar and fructose and/or a genetic predisposition can be the underlying caus.

31 Aug 2018

New guideline developed to help physicians diagnose idiopathic pulmonary fibrosis

A new international guideline has been developed to help physicians diagnosis idiopathic pulmonary fibrosis, a rare and often fatal lung disease whose cause is unknown.

31 Aug 2018

Study shows B cells could play reciprocal roles in pathogenesis of systemic sclerosis

Systemic sclerosis (SSc, also known as scleroderma), a connective tissue disorder of autoimmune etiology, is characterized by excessive fibrosis in the skin and various internal organs.

30 Aug 2018

Vertex, Genomics team up to improve discovery of precision medicines

Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) and Genomics plc today announced a three-year collaboration, extendable to five years, to use human genetics and machine learning to improve discovery of targets for precision medicines, and to advance understanding of the clinical impact of human genetic variation and patient stratification in diseases with significant unmet need.

30 Aug 2018

New lung tissue-on-a-chip system offers rapid testing of potential anti-fibrotic treatments

Pulmonary fibrosis is one of the most common and serious types of lung disease. Now NIBIB-funded researchers have developed an in vitro lung tissue-on-a-chip system that mimics lung fibrosis, offering rapid testing of potential new anti-fibrotic treatments.

28 Aug 2018

Pancreas' network of enzyme ducts resembles formation of rivers

With methods used to analyze road systems and rivers researchers from the University of Copenhagen have studied the formation of the pancreas' network of ducts transporting digestive enzymes in mice.

27 Aug 2018

Left atrial fibrosis may indicate high risk of arrhythmias in trained endurance athletes

Left atrial fibrosis may explain the increased risk of arrhythmias seen in highly trained endurance athletes, according to research presented today at ESC Congress 2018.

27 Aug 2018

Insilico announces presentation of latest research at Global Precision Medicine & Biomarkers Leaders Summit

Insilico Medicine, a Rockville-based company specializing in the application of next-generation artificial intelligence for drug discovery, biomarker development and aging research, announces the presentation of its CTO, Alex Zhebrak at the 5th Global Precision Medicine & Biomarkers Leaders Summit, September 13-14, 2018, Munich, Germany.

27 Aug 2018

Evotec collaborates with CENTOGENE to develop compounds to treat rare genetic diseases

CENTOGENE today announced that Evotec AG and CENTOGENE AG entered into a global strategic collaboration agreement for joint drug discovery projects, developing compounds to treat rare genetic diseases.

27 Aug 2018

Newly discovered target may prevent progression of liver injury to cancer

Problems like obesity and alcoholism appear to chronically trigger in the liver a receptor known to amplify inflammation in response to invaders like bacteria, scientists report.

27 Aug 2018

Forbius receives $18.75 million grant from CPRIT for Phase 2a development of AVID100

Forbius announced today that it has been awarded a Product Development grant totaling $18.75 million from the Cancer Prevention and Research Institute of Texas.

25 Aug 2018

UAB receives NIH grant to continue evaluation of new medication for IPF

The University of Alabama at Birmingham has received a grant from the National Institutes of Health totaling $8.9 million to fund a multiyear program evaluating the role of a new medication in a clinical trial for patients suffering from idiopathic pulmonary fibrosis

24 Aug 2018

Scientists work towards solving mystery of incurable blood diseases

Scientists may be on the road to solving the mystery of a group of mostly incurable blood diseases called myelodysplastic syndromes, which cause people to have immature, malfunctioning bone marrow cells that fuel a diverse set of health problems and can lead to leukemia.

23 Aug 2018

Innovation in Wound Care

There are many definitions of hard-to-heal. More conventionally, it's based on underlying etiology of the wound, but in practice it's any wound that has not healed within a timely fashion. This is often due to a lack of coordinated care.

From Neem Biotech 22 Aug 2018

Scleroderma Foundation names Tulane professor as 'Doctor of the Year'

Dr. Lesley Ann Saketkoo, an associate professor of clinical medicine at Tulane University School of Medicine, has been named Doctor of the Year by the Scleroderma Foundation. The award recognizes leadership and commitment to the community battling scleroderma, a disabling and life-limiting multi-organ autoimmune disease with progressive lung, heart, kidney, gastrointestinal tract and/or vascular involvement.

21 Aug 2018

Gene therapy with telomerase does not increase cancer risk, study shows

Negative results and findings in science are perhaps less newsworthy, but they are no less important. Particularly when, as in this case, they demonstrate that a possible new therapeutic pathway against idiopathic pulmonary fibrosis and other diseases associated to short telomeres is in fact safe.

21 Aug 2018

Scientists discover peptides that can be used as new antibiotic candidates

The human body produces many antimicrobial peptides that help the immune system fend off infection. Scientists hoping to harness these peptides as potential antibiotics have now discovered that other peptides in the human body can also have potent antimicrobial effects, expanding the pool of new antibiotic candidates.

21 Aug 2018

Study finds rise in cases of progressive massive fibrosis among U.S. coal miners

The number of cases of progressive massive fibrosis (PMF) among U.S. coal miners has risen during the past two decades, even as the number of coal miners has declined, according to new research published online in the Annals of the American Thoracic Society.

17 Aug 2018

New project to combat DMD-related fibrosis receives major funding boost

Duchenne muscular dystrophy is one of the most common congenital diseases in the world, affecting one in 3,500 Canadian males. DMD is caused by mutations in the dystrophin gene that results in progressive muscle degeneration and there are currently no effective treatments for DMD.

17 Aug 2018

Fibrosis News and Research

Further Reading

UA researchers receive $4.4 million grant to focus on idiopathic pulmonary fibrosis

Novel approaches for personalized risk prognosis and individualized treatment of NAFLD

New guideline developed to help physicians diagnose idiopathic pulmonary fibrosis

Study shows B cells could play reciprocal roles in pathogenesis of systemic sclerosis

Vertex, Genomics team up to improve discovery of precision medicines

New lung tissue-on-a-chip system offers rapid testing of potential anti-fibrotic treatments

Pancreas' network of enzyme ducts resembles formation of rivers

Left atrial fibrosis may indicate high risk of arrhythmias in trained endurance athletes

Insilico announces presentation of latest research at Global Precision Medicine & Biomarkers Leaders Summit

Evotec collaborates with CENTOGENE to develop compounds to treat rare genetic diseases

Newly discovered target may prevent progression of liver injury to cancer

Forbius receives $18.75 million grant from CPRIT for Phase 2a development of AVID100

UAB receives NIH grant to continue evaluation of new medication for IPF

Scientists work towards solving mystery of incurable blood diseases

Innovation in Wound Care

Scleroderma Foundation names Tulane professor as 'Doctor of the Year'

Gene therapy with telomerase does not increase cancer risk, study shows

Scientists discover peptides that can be used as new antibiotic candidates

Study finds rise in cases of progressive massive fibrosis among U.S. coal miners

New project to combat DMD-related fibrosis receives major funding boost

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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