Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Brain protein CUL5 protects neurons by clearing toxic tau clumps

Researchers at UC San Francisco have identified a hazardous waste collector in the brain that disposes of the toxic clumps of tau protein that can lead to dementia.

28 Jan 2026

Eating melatonin-rich foods is linked to lower obesity and depression rates

This cross-sectional analysis of 8,320 Brazilian adults quantified melatonin intake from habitual diets and examined associations with multiple chronic health outcomes. Higher dietary melatonin intake was inversely associated with obesity and depression in a non-linear pattern, with no significant associations observed for other conditions.

28 Jan 2026

How DNA and life experiences leave distinct marks on the human immune system

Using single-cell epigenomic profiling of immune cells from 110 individuals, researchers show that genetic variation and environmental exposures shape the human immune system through distinct DNA methylation mechanisms. Genetic effects concentrate within gene bodies of memory cells, while environmental exposures primarily remodel regulatory regions in naive immune cells.

28 Jan 2026

UVA Health scientists pioneer a new way to create vaccines far more quickly than ever before

UVA Health scientists are reporting promising success as they pioneer a new way to create vaccines far more quickly, nimbly and inexpensively than ever before.

28 Jan 2026

Exploring Targeted Protein Degradation as a New Strategy to Tackle Antimicrobial Resistance

Targeted protein degradation presents a promising strategy to address antimicrobial resistance, focusing on innovative approaches for gram-negative bacteria.

28 Jan 2026

Four-biomarker blood panel enhances the detection of pancreatic ductal adenocarcinoma

A four-biomarker blood panel of aminopeptidase N (ANPEP), polymeric immunoglobulin receptor (PIGR), CA19-9, and thrombospondin-2 (THBS2) enhanced the detection of pancreatic ductal adenocarcinoma (PDAC) compared to measuring CA19-9 levels alone.

28 Jan 2026

Newly discovered compound can advance the body's internal clock

A Japanese research team has discovered a new compound that can advance the body's internal clock—offering hope for faster recovery from jet lag and better adaptation to night-shift work.

28 Jan 2026

New peptide targets the root causes of recurring seizures

New study suggests that an experimental peptide developed at the Hebrew University may reduce recurring seizures and support brain function by targeting underlying oxidative stress and inflammation processes linked to epilepsy.

28 Jan 2026

Redefining early detection for type 1 diabetes

Researchers have identified a protein pattern that, already at birth, looks markedly different in those who later go on to develop type 1 diabetes. The findings show that a combination of several factors during pregnancy increases the risk of the child later developing the disease. The study is published in Nature Communications and was led by researchers at Linköping University, Sweden, and the University of Florida, USA.

28 Jan 2026

A shingles vaccine may delay dementia onset

Research indicates the herpes zoster vaccine may reduce dementia rates by 2%, highlighting its potential role in promoting brain health in aging populations.

28 Jan 2026

Clinical trial aims to improve survival for patients with recurrent head and neck cancer

A newly approved National Cancer Institute-funded clinical trial aims to improve survival for head and neck cancer patients whose disease returns after radiation therapy – a setback that affects up to 40% of patients and is often associated with poor outcomes.

27 Jan 2026

Purdue researchers discover new therapeutic target for triple-negative breast cancer

A Purdue University team led by Kyle Cottrell has discovered a new therapeutic target for triple-negative breast cancer.

27 Jan 2026

Overactive protein cleanup disrupts nuclear pores in neurodegenerative disease

When it comes to neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and certain forms of dementia, researchers have known that protein quality control and damage to the nuclear pore are key players.

27 Jan 2026

Brain-specific enzyme drives branching and extension of O-mannose glycans

Gifu University scientists have uncovered how a brain-specific enzyme reshapes protein-linked sugar chains to facilitate the formation of complex glycans essential for normal brain function.

27 Jan 2026

Gut problems may shape Parkinson’s disease progression through the gut-brain axis

This narrative review examines how gastrointestinal dysfunction, gut dysbiosis, and altered gut-brain axis signaling are closely associated with the onset and progression of Parkinson’s disease. It synthesizes evidence supporting a possible bottom-up disease model while highlighting integrative, gut-targeted strategies as adjuncts to symptom management rather than proven disease-modifying therapies.

27 Jan 2026

New research initiative aims to develop retinal screening tool for Alzheimer's

The human eye may literally become a window revealing the earliest signals of Alzheimer's disease, thanks to a new federally funded research initiative at Oregon Health & Science University.

27 Jan 2026

Brain organoids reveal glioblastoma's secrets and therapy resistance

UCLA scientists have developed advanced miniature 3D tumor organoid models that make it possible to study glioblastoma tumors in a setting that closely mirrors the human brain, shedding light on how the aggressive cancer interacts with surrounding brain cells and the immune system to become more invasive and resistant to therapy.

27 Jan 2026

Protein News and Research

Further Reading

Brain protein CUL5 protects neurons by clearing toxic tau clumps

Eating melatonin-rich foods is linked to lower obesity and depression rates

How DNA and life experiences leave distinct marks on the human immune system

UVA Health scientists pioneer a new way to create vaccines far more quickly than ever before

Exploring Targeted Protein Degradation as a New Strategy to Tackle Antimicrobial Resistance

Four-biomarker blood panel enhances the detection of pancreatic ductal adenocarcinoma

Newly discovered compound can advance the body's internal clock

New peptide targets the root causes of recurring seizures

Redefining early detection for type 1 diabetes

A shingles vaccine may delay dementia onset

Clinical trial aims to improve survival for patients with recurrent head and neck cancer

Purdue researchers discover new therapeutic target for triple-negative breast cancer

Overactive protein cleanup disrupts nuclear pores in neurodegenerative disease

Brain-specific enzyme drives branching and extension of O-mannose glycans

Gut problems may shape Parkinson’s disease progression through the gut-brain axis

New research initiative aims to develop retinal screening tool for Alzheimer's

Brain organoids reveal glioblastoma's secrets and therapy resistance

Scientists discover spindle's self-repair mechanism for accurate cell division

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