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Low-cost CRISPR-based paper strip test offers rapid influenza diagnosis

Fewer than one percent of people who get the flu every year get tested, in part because most tests require trained personnel and expensive equipment.

21 Jun 2024

Combination therapy shows great promise as a new strategy against advanced lung cancer

Adding an anti-inflammatory drug to anti-PD1 checkpoint inhibitor immunotherapy has shown great promise as a new strategy against advanced lung cancer, based on results from a small clinical trial led by investigators at the Abramson Family Cancer Center at the University of Pennsylvania Perelman School of Medicine.

21 Jun 2024

Using deep learning to design synthetic soluble versions of cell membrane proteins

Many drug and antibody discovery pathways focus on intricately folded cell membrane proteins: when molecules of a drug candidate bind to these proteins, like a key going into a lock, they trigger chemical cascades that alter cellular behavior.

21 Jun 2024

Advances in organoids and embryonic models pose no risk to personhood, expert argues

Advances in organoids and embryonic models of human development have the potential to prompt social and existential questions - e.g., what defines human individuality? However, bioethicist Insoo Hyun of Harvard Medical School and the Museum of Science in Boston says that these models have the potential to strengthen rather than weaken the concept of human individuality when considered within the philosophical frameworks of "personhood" and sentience.

20 Jun 2024

WEHI spinout aims to revolutionize the development of cancer drugs

Australia has cemented its role in becoming a major player in the next generation of medicines with the launch of Ternarx – a globally competitive biotechnology company dedicated to finding new treatments for hard-to-treat cancers.

20 Jun 2024

JAK inhibitor ruxolitinib enhances immunotherapy in Hodgkin lymphoma patients

Checkpoint inhibitor therapies can be thought of as the molecular "brake release" for the immune system.

20 Jun 2024

One copy of the Christchurch variant may confer protection against familial Alzheimer's disease

A scientific story that began with a discovery in just one extraordinary patient is now panning out. In 2019, an international team that included researchers from two Mass General Brigham hospitals - Mass Eye and Ear and Massachusetts General Hospital (MGH) - reported on the case of a patient who did not develop cognitive impairment until her late 70s, despite being part of a family at extremely high genetic risk for developing early-onset Alzheimer's disease.

20 Jun 2024

New Swiss research institute to pioneer immune engineering and global child health

“Swiss research institute established to focus on immune engineering and advancing global child and adolescent health.”

19 Jun 2024

New research uncovers how some individuals avoid COVID-19 infection

Scientists have discovered novel immune responses that help explain how some individuals avoid getting COVID-19.

19 Jun 2024

Research shows mechanistic link between amino acid transport and common fetal conditions

Common complications of pregnancy affecting fetal size may be caused by irregularities in the transport of amino acids across the placenta - a finding with therapeutic implications.

18 Jun 2024

Diet quality in America shows modest improvement from 1999 to 2020

Poor diet continues to take a toll on American adults. It's a major risk factor for obesity, type 2 diabetes, cardiovascular disease, and certain cancers, and more than one million Americans die every year from diet-related diseases, according to the Food and Drug Administration.

17 Jun 2024

How ketone bodies contribute to brain health and memory preservation

The ketogenic diet has its fanatics and detractors among dieters, but either way, the diet has a scientifically documented impact on memory in mice.

17 Jun 2024

Gyros Protein Technologies introduces Gyrolab Generic Anti-AAV Kit to support gene therapy development

Ready-to-use kit enables detection of binding antibodies against AAV vectors without the need for serotype-specific assays.

From Gyros Protein Technologies AB 17 Jun 2024

Enterprise Therapeutics appoints Dr Renu Gupta as Chief Medical Officer and Dr Janet Hammond as Non-Executive Director

Appointments bring additional respiratory and late clinical-stage drug development experience as Company commences Phase 2a clinical trial of its lead asset.

From Enterprise Therapeutics Ltd 17 Jun 2024

St. Jude researchers uncover NLRC5's role in immune response and cell death

The innate immune system is responsible for protecting the human body from threats that could cause disease or infection.

14 Jun 2024

AI-driven alerts improve patient care escalation and survival rates in hospitals

Deploying and evaluating a machine learning intervention to improve clinical care and patient outcomes is a key step in moving clinical deterioration models from byte to bedside, according to a June 13 editorial in Critical Care Medicine that comments on a Mount Sinai study published in the same issue.

13 Jun 2024

New research sheds light on IL-23's role in chronic inflammatory bowel diseases

Scientists at Weill Cornell Medicine discovered a previously unknown link between two key pathways that regulate the immune system in mammals - a finding that impacts our understanding of chronic inflammatory bowel diseases (IBD).

12 Jun 2024

Synthetic cell mimics immune response via symmetry breaking

In a feat aimed at understanding how cells move and creating new ways to shuttle drugs through the body, scientists at Johns Hopkins Medicine say they have built a minimal synthetic cell that follows an external chemical cue and demonstrates a governing principle of biology called "symmetry breaking."

12 Jun 2024

UC San Diego engineers develop algae-based microrobots for lung cancer treatment

Engineers at the University of California San Diego have developed microscopic robots, known as microrobots, capable of swimming through the lungs to deliver cancer-fighting medication directly to metastatic tumors.

12 Jun 2024

Enhancing CAR-T cell therapy with biodegradable scaffolds

CAR-T cell therapies are transforming the treatment of previously incurable blood cancers. Six approved CAR-T products have been administered to more than 20,000 people, and more than 500 clinical trials are underway.

12 Jun 2024

Therapeutics News and Research

Low-cost CRISPR-based paper strip test offers rapid influenza diagnosis

Combination therapy shows great promise as a new strategy against advanced lung cancer

Using deep learning to design synthetic soluble versions of cell membrane proteins

Advances in organoids and embryonic models pose no risk to personhood, expert argues

WEHI spinout aims to revolutionize the development of cancer drugs

JAK inhibitor ruxolitinib enhances immunotherapy in Hodgkin lymphoma patients

One copy of the Christchurch variant may confer protection against familial Alzheimer's disease

New Swiss research institute to pioneer immune engineering and global child health

New research uncovers how some individuals avoid COVID-19 infection

Research shows mechanistic link between amino acid transport and common fetal conditions

Diet quality in America shows modest improvement from 1999 to 2020

How ketone bodies contribute to brain health and memory preservation

Gyros Protein Technologies introduces Gyrolab Generic Anti-AAV Kit to support gene therapy development

Enterprise Therapeutics appoints Dr Renu Gupta as Chief Medical Officer and Dr Janet Hammond as Non-Executive Director

St. Jude researchers uncover NLRC5's role in immune response and cell death

AI-driven alerts improve patient care escalation and survival rates in hospitals

New research sheds light on IL-23's role in chronic inflammatory bowel diseases

Synthetic cell mimics immune response via symmetry breaking

UC San Diego engineers develop algae-based microrobots for lung cancer treatment

Enhancing CAR-T cell therapy with biodegradable scaffolds

Industry Focus eBook - Biotechnology (4th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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