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Research reveals LEGO-like stacking of protein complexes

When hemoglobin undergoes just one mutation, the protein complexes stick to one another, stacking like LEGO blocks to form long, stiff filaments.

29 Aug 2017

Research findings potentially open door to new treatments for eye trauma and retinal disease

Cells within an injured mouse eye can be coaxed into regenerating neurons and those new neurons appear to integrate themselves into the eye's circuitry, new research shows. The findings potentially open the door to new treatments for eye trauma and retinal disease.

28 Aug 2017

Researchers use zebrafish animal model to explore drug-seeking behavior

As the opioid crisis escalates, the science behind addiction remains poorly understood. To address this need, researchers at University of Utah Health devised a system that allowed zebrafish, a small tropical fish, to self-administer doses of hydrocodone, an opioid commonly prescribed to people for pain.

26 Aug 2017

New review explores evolving treatments and future therapies for osteoarthritis pain

A new review by David A. Walsh and Joanne Stocks in the September 2017 issue of SLAS Discovery (formerly the Journal of Biomolecular Screening) explores evolving treatments and future therapies for osteoarthritis (OA) pain.

26 Aug 2017

Tumor irradiation may prolong survival of NSCLC patients undergoing novel chemotherapy formulation

Patients with unresectable, or inoperable, lung cancer are often given a dismal prognosis, with low rates of survival beyond a few years.

26 Aug 2017

Distinguishing biothreat look-alikes could aid biological surveillance

Biological "detectives" are tracking down biothreats such as the bacteria that causes tularemia ("rabbit fever"), but they constantly face the challenge of avoiding false positives.

26 Aug 2017

New drug shows promising results for treating spinal muscular atrophy

A drug developed by an Iowa State University biomedical researcher as a potential treatment for spinal muscular atrophy showed promising results in a recently published study.

26 Aug 2017

Yale experts uncover genes associated with immune response to flu vaccination

Yale experts and their partners in a national research consortium have identified several genes and gene clusters associated with the immune response to flu vaccination.

26 Aug 2017

NIH funds BU ADC with $5.4 million grant to advance research on Alzheimer's disease

The National Institutes of Health/National Institute on Aging has awarded the Boston University Alzheimer's Disease Center a three-year, $5.4 million grant to continue research on ways to reduce the human and economic costs of Alzheimer's disease (AD) through the advancement of knowledge.

26 Aug 2017

Scientists develop new system to identify and characterize regulatory DNA sequences

Scientists from the Children's Medical Center Research Institute at UT Southwestern have developed an innovative system to identify and characterize the molecular components that control the activities of regulatory DNA sequences in the human genome.

24 Aug 2017

Increased enzyme production by the liver causes fatty liver, obesity and insulin resistance

In mice that are given a high-fat diet, an increased production of the enzyme DPP4 by the liver promotes an increase in body fat, the development of fatty liver disease and insulin resistance.

24 Aug 2017

Long non-coding RNAs could represent novel male infertility drug targets

Scientists have found distinctive portions of genetic material--known as lncRNAs--that help sperm develop. Male mice lacking a particular lncRNA have low sperm count, suggesting lncRNAs could represent novel infertility drug targets.

24 Aug 2017

Acid-sensing receptor may have significant relevance to physiological response in panic disorder

Panic disorder is a syndrome characterized by spontaneous and recurrent episodes of incapacitating anxiety. It typically emerges during adolescence or early adulthood and can take an exhausting emotional and physical toll on the body.

24 Aug 2017

Researchers identify important adenovirus receptor in macrophages of mice

Adenoviral infections have a mild disease progression in healthy people, but it can be dangerous for immunocompromised people.

24 Aug 2017

Variations in ancient mitochondrial DNA may play key role in predisposition to ASD

Mitochondria, the tiny structures inside our cells that generate energy, may play a key role in autism spectrum disorders (ASD).

23 Aug 2017

New international research project identifies subtypes of ocular melanoma

A new international research project, involving the University of Liverpool's leading eye cancer research group, has identified specific subtypes of ocular melanoma that will help develop improved management strategies and therapies in the future.

23 Aug 2017

Researchers describe mechanism linking HPV infection and cancer

Infection with human papillomavirus (HPV) is the primary cause of cervical cancer and a subset of head and neck cancers worldwide.

23 Aug 2017

Our body contains more diverse microbes than previously known, new survey suggests

A new survey of DNA fragments circulating in human blood suggests our bodies contain vastly more diverse microbes than anyone previously understood.

23 Aug 2017

New blood test can predict drug resistance in patients with advanced prostate cancer

When bacteria develop antibiotic resistance, treatment with these medications becomes ineffective. Similarly, tumor cells can also change in such a way that renders them resistant to particular medications.

22 Aug 2017

Id genes found to play crucial role in heart development

Researchers from Sanford Burnham Prebys Medical Discovery Institute (SBP), the Cardiovascular Institute at Stanford University and other institutions were surprised to discover that the four genes in the Id family play a crucial role in heart development, telling undifferentiated stem cells to form heart tubes and eventually muscle.

22 Aug 2017

Genetic News and Research

Research reveals LEGO-like stacking of protein complexes

Research findings potentially open door to new treatments for eye trauma and retinal disease

Researchers use zebrafish animal model to explore drug-seeking behavior

New review explores evolving treatments and future therapies for osteoarthritis pain

Tumor irradiation may prolong survival of NSCLC patients undergoing novel chemotherapy formulation

Distinguishing biothreat look-alikes could aid biological surveillance

New drug shows promising results for treating spinal muscular atrophy

Yale experts uncover genes associated with immune response to flu vaccination

NIH funds BU ADC with $5.4 million grant to advance research on Alzheimer's disease

Scientists develop new system to identify and characterize regulatory DNA sequences

Increased enzyme production by the liver causes fatty liver, obesity and insulin resistance

Long non-coding RNAs could represent novel male infertility drug targets

Acid-sensing receptor may have significant relevance to physiological response in panic disorder

Researchers identify important adenovirus receptor in macrophages of mice

Variations in ancient mitochondrial DNA may play key role in predisposition to ASD

New international research project identifies subtypes of ocular melanoma

Researchers describe mechanism linking HPV infection and cancer

Our body contains more diverse microbes than previously known, new survey suggests

New blood test can predict drug resistance in patients with advanced prostate cancer

Id genes found to play crucial role in heart development

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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