Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Are advanced dementia staging and severity of neuropsychiatric behavioral symptoms associated with the likelihood of divorce or separation in older adulthood?

Researchers evaluated associations between neuropsychiatric behavioral symptoms, dementia staging, and divorce/separation.

2 Mar 2023

Research investigates roles of neurotrophic factors on cognition in Alzheimer's patients carrying APOE ε4

Researchers investigate the role of neurotrophic factors on the cognitive performance of Alzheimer’s disease patients carrying the apolipoprotein E 4 gene.

1 Mar 2023

Gene variant found in individuals of African ancestry dramatically boosts Alzheimer's risk

Stanford Medicine scientists and their colleagues have discovered that a gene variant found almost exclusively in the genomes of individuals of African ancestry dramatically boosts Alzheimer's risk. About 4% of African Americans carry this variant.

1 Mar 2023

Exploring the neuroprotective potential of cell-penetrating peptides, extracellular vesicles, and micro ribonucleic acids

In a recent review published in Biomedicines, researchers explored extracellular vesicles (EVs), cell-penetrating peptides (CPPs), and micro ribonucleic acids (miRNAs) as therapies for neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD).

1 Mar 2023

Breaking apart certain proteins may offer a pathway to treat Alzheimer's diease

Certain diseases, including Alzheimer's, are currently considered "undruggable" because traditional small molecule drugs can't interfere with the proteins responsible for the illnesses.

1 Mar 2023

New screening tool can efficiently assess cognition issues in older adults

A self-administered screening tool, developed by Cleveland Clinic researchers, can effectively and efficiently assess cognition issues in older adults.

1 Mar 2023

Taking vitamin D associated with living dementia-free for longer time

Taking vitamin D supplements may help ward off dementia, according to a new, large-scale study.

1 Mar 2023

Scientists working to create revolutionary biocomputers powered by brain organoids

Artificial intelligence (AI) has long been inspired by the human brain. This approach proved highly successful: AI boasts impressive achievements – from diagnosing medical conditions to composing poetry.

28 Feb 2023

New evidence of four distinct pain trajectories in nursing home residents

Despite awareness that pain is common in nursing home residents, there has been minimal attention focused on how this pain changes over time.

27 Feb 2023

The natural history of tau accumulation and the impact of disease stage and reference region on the magnitude and effect size of regional change

Researchers performed serial tau imaging with 18F-MK6240 to detect tau accumulation in cognitively unimpaired beta-amyloid negative Alzheimer’s disease patients as well as those with mild cognitive impairment who were Aβ+ at baseline.

27 Feb 2023

Dementia care programs help, if caregivers can find them

There's no cure, yet, for Alzheimer's disease. But dozens of programs developed in the past 20 years can improve the lives of both people living with dementia and their caregivers.

27 Feb 2023

Comprehensive plan for phasing out the use of animals in experimentation

PETA scientists have just released a new edition of the groundbreaking Research Modernization Deal (RMD), the world's first comprehensive plan for phasing out the use of animals in experimentation. The update is packed with new, cutting-edge information and reflects the latest scientific developments and regulatory changes since the RMD was first introduced in 2018.

27 Feb 2023

Apolipoprotein E4 promotes the development of Alzheimer’s disease

Researchers characterize the effects of neuronal apolipoprotein E4 on Alzheimer’s disease-associated pathology.

23 Feb 2023

New ensemble learning model could predict dementia in older drivers with excellent accuracy

Using ensemble learning techniques and longitudinal data from a large naturalistic driving study, researchers at Columbia University's Mailman School of Public Health, Fu Foundation School of Engineering and Applied Science, and Vagelos College of Physicians and Surgeons have developed a novel, interpretable and highly accurate algorithm for predicting mild cognitive impairment and dementia in older drivers.

23 Feb 2023

Oleic acid: Principal component of olive oil responsible for many health-promoting properties

Oleic acid, the principal component of olive oil, has properties that help to prevent cancer and Alzheimer's disease and to lower cholesterol.

23 Feb 2023

Disabilities in people with heart disease underreported in clinical trials

Disabilities were underreported in clinical trial data and commonly used as a basis for exclusion from trial participation in an analysis of 80 recent trials involving cardiovascular outcomes, according to a study being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

23 Feb 2023

Study identifies placental growth factor as a biomarker for vascular cognitive impairment

Measuring a key blood molecule may help doctors diagnose whether or how much impaired blood flow to a patient's brain is contributing to dementia or cognitive problems, according to a new study led by a UCLA Health researcher.

23 Feb 2023

Study links obesity with 21 Alzheimer's disease-related genes

In a new study, researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) link obesity with 21 Alzheimer's disease-related genes, providing a potential mechanistic explanation for why Alzheimer's is sometimes more frequent among adults who experienced obesity in midlife.

22 Feb 2023

Mount Sinai study sheds new light on the role of DNA methylation in Alzheimer's disease

Mount Sinai researchers have published a study in Alzheimer's & Dementia: The Journal of the Alzheimer's Association that sheds new light on the role of DNA methylation in Alzheimer's disease (AD).

22 Feb 2023

Study reports that depleting gut bacteria in mice with genetic risk for AD reduces neuropathology in a sex-dependent manner

Researchers highlight recent research investigating whether gut microbiota regulates tau pathology and tau-mediated neurodegeneration in an ApoE isoform–dependent manner.

21 Feb 2023

Alzheimer's Disease News and Research

Further Reading

Are advanced dementia staging and severity of neuropsychiatric behavioral symptoms associated with the likelihood of divorce or separation in older adulthood?

Research investigates roles of neurotrophic factors on cognition in Alzheimer's patients carrying APOE ε4

Gene variant found in individuals of African ancestry dramatically boosts Alzheimer's risk

Exploring the neuroprotective potential of cell-penetrating peptides, extracellular vesicles, and micro ribonucleic acids

Breaking apart certain proteins may offer a pathway to treat Alzheimer's diease

New screening tool can efficiently assess cognition issues in older adults

Taking vitamin D associated with living dementia-free for longer time

Scientists working to create revolutionary biocomputers powered by brain organoids

New evidence of four distinct pain trajectories in nursing home residents

The natural history of tau accumulation and the impact of disease stage and reference region on the magnitude and effect size of regional change

Dementia care programs help, if caregivers can find them

Comprehensive plan for phasing out the use of animals in experimentation

Apolipoprotein E4 promotes the development of Alzheimer’s disease

New ensemble learning model could predict dementia in older drivers with excellent accuracy

Oleic acid: Principal component of olive oil responsible for many health-promoting properties

Disabilities in people with heart disease underreported in clinical trials

Study identifies placental growth factor as a biomarker for vascular cognitive impairment

Study links obesity with 21 Alzheimer's disease-related genes

Mount Sinai study sheds new light on the role of DNA methylation in Alzheimer's disease

Study reports that depleting gut bacteria in mice with genetic risk for AD reduces neuropathology in a sex-dependent manner

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