Atherosclerosis News and Research

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Atherosclerosis is the progressive buildup of plaque - the fatty deposits and other cells - in the inner walls of the arteries. The condition is a consequence of elevated cholesterol and for many it's a silent disease, with no visible signs or symptoms. The disease can begin in early adulthood and continues to progress for the rest of a person's life. Despite the serious nature of atherosclerosis, many people do not understand how it develops and progresses.

PGxHealth presents results from studies using FAMILION genetic testing at 2010 AHA

Clinical Data, Inc., today announced that results of studies using its FAMILION® genetic testing were presented at the 2010 American Heart Association (AHA) meeting. PGxHealth, a division of Clinical Data, together with its collaborators, presented results from the largest, most comprehensive studies of genetic variation associated with certain cardiac conditions that were revealed using FAMILION testing.

15 Nov 2010

TU/e researchers image stages of calcification process in atherosclerosis

Atherosclerosis is characterized by hardening and thickening of artery walls, with serious health consequences. Researchers at Eindhoven University of Technology (TU/e) have imaged the stages in the calcification process at a nanometer scale.

15 Nov 2010

Novel mechanism regulating circadian rhythm identified

Scientists from the Florida campus of The Scripps Research Institute have identified for the first time a novel mechanism that regulates circadian rhythm, the master clock that controls the body's natural 24-hour physiological cycle. These new findings could provide a new target not only for jet lag, shift work, and sleep disturbances, but also for disorders that result from circadian rhythm disruption, including diabetes and obesity as well as some types of cancer.

11 Nov 2010

Amarin reports $31.4 million cash balance for third quarter 2010

Amarin Corporation plc, a clinical-stage biopharmaceutical company focused on cardiovascular disease, today reported its financial and operational results for the three-month period ended September 30, 2010.

10 Nov 2010

Positive results from XOMA 052 study in patients with uveitis of Behcet's disease

XOMA Ltd., a leader in the discovery and development of therapeutic antibodies, announced additional positive results from an open-label pilot study of XOMA 052 in patients with uveitis of Behcet's disease who were suffering from vision-threatening exacerbations despite maximal doses of immunosuppressive medicines.

10 Nov 2010

Researchers to determine levels of stroke risk in patients with narrowed brain arteries

Neurological researchers at Rush University Medical Center are part of a multicenter, National Institutes of Health (NIH) study to determine the levels of stroke risk and stroke recurrence in patients with narrowed brain arteries.

10 Nov 2010

BioInvent receives FDA IND clearance for BI-204 Phase II trial in cardiovascular disease

BioInvent International AB today announces IND clearance from the U.S. Food & Drug Administration (FDA) to initiate a Phase II study for BI-204. BI-204 is a human monoclonal antibody that specifically targets oxidized forms of a low-density lipoprotein (LDL) which has been linked to increased inflammatory processes leading to plaque formation in the blood vessel walls. BI-204 is being co-developed with Genentech for secondary prevention of cardiovascular events in patients with acute coronary syndrome (ACS).

10 Nov 2010

DHA protects brain tissue and promotes recovery in acute ischemic stroke

Research led by Dr. Nicolas Bazan, Boyd Professor, Villere Chair, and Director of the Neuroscience Center of Excellence at LSU Health Sciences Center, has shown that Docosahexaenoic acid (DHA), a component of fish oil, is a powerful therapeutic agent that can protect brain tissue and promote recovery in an experimental model of acute ischemic stroke, even when treatment is delayed by up to five hours.

9 Nov 2010

Multidetector CT helps pinpoint causes of ischemic stroke

Multidetector computed tomography (CT) helps pinpoint the causes of ischemic strokes, the most common type of stroke, potentially speeding the delivery of life-saving treatments, according to a study published online and in the January issue of Radiology.

9 Nov 2010

Limiting inflammation can control accumulation of carotid atherosclerosis in RA patients

New data presented this week at the American College of Rheumatology Annual Scientific Meeting in Atlanta show that systemic inflammation and rheumatoid arthritis disease activity may contribute to the progression of atherosclerosis in people with RA. The data also show that this progression may be modified favorably by TNF inhibitors and detrimentally by glucocorticoids.

8 Nov 2010

TRPM7 protein plays a key role in maintenance of magnesium homeostasis

An international team led by researchers at the University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School has published new findings that demonstrate how a specific protein controls the body's ability to balance magnesium levels. Magnesium is an essential element for good health and is critical to more than 300 biochemical reactions that occur in the body.

8 Nov 2010

Statin drugs do not benefit pediatric lupus patients

Lupus puts children at higher risk for coronary artery disease when they become adults, but routinely using statins doesn't provide enough benefit to warrant their regular use in children and adolescents, according to the largest study of pediatric lupus patients to date.

8 Nov 2010

Spherix subsidiary awarded $469,479 grant under Patient Protection and Affordable Care Act

Spherix Incorporated, an innovator in biotechnology for therapy in diabetes, metabolic syndrome and atherosclerosis; and provider of technical and regulatory consulting services to food, supplement, biotechnology and pharmaceutical companies, today announced that its subsidiary, Biospherics Incorporated, has been awarded $469,479 under HR: 3590 – Patient Protection and Affordable Care Act in immediately available funds.

4 Nov 2010

Immune Network to complete patient enrollment in Phase 2b imm01 trial for tuberculosis

Immune Network Ltd. a company in the business of discovery and development of immune-based therapies, today announced that patient enrollment will be completed next week for the company's future partner Immunitor's Phase 2b imm01 trial of V5 immunotherapy in 120 patients with tuberculosis.

3 Nov 2010

Atrium completes enrollment in iCAST Atrium Registry Ultrasound Study

Atrium Medical Corporation is pleased to announce that the final patient was recently enrolled in the iCAST™ Atrium Registry Ultrasound Study (iCARUS). This study is a prospective, multi-center clinical trial studying the safety and efficacy of the Atrium iCAST™ Balloon Expandable Covered Stent in patients with occlusive disease of the iliac artery.

2 Nov 2010

New findings pave way to improve early detection of ovarian cancer

A drug in testing to treat atherosclerosis significantly inhibited growth of ovarian cancer in both human cell lines and mouse models, the first such report of a peptide being used to fight malignancies, according to a study by researchers at UCLA's Jonsson Comprehensive Cancer Center.

2 Nov 2010

Merck reports $342 million net income for 2010 third quarter

Merck & Co., Inc. today announced financial results for the third quarter of 2010. The company reported non-GAAP (generally accepted accounting principles) earnings per share (EPS) for the third quarter of $0.85, which excludes purchase accounting adjustments, restructuring costs, merger-related expenses and a $950 million legal reserve.

29 Oct 2010

Stryker enters agreement to acquire assets of Neurovascular division of Boston Scientific

Stryker Corporation announced today a definitive agreement to acquire the assets of the Neurovascular division of Boston Scientific in an all cash transaction for $1.5 billion, which includes $100 million of milestone payments.

From Stryker 29 Oct 2010

Archimedes launches AOA web application to help healthcare organizations

Archimedes Inc., a healthcare modeling company, announced today the launch of the Archimedes Outcomes Analyzer (AOA), a web application that expands access to data sets generated by the Archimedes Model, a large-scale simulation model that calculates clinical and cost outcomes, and answers complex healthcare questions.

26 Oct 2010

Prevention of vascular diseases needed to avoid tsunami of cases

Canada urgently needs to focus on prevention of vascular diseases to avoid the burden from the expected tsunami of cases, says noted stroke expert Dr. Robert Côté, delivering the Heart and Stroke Foundation of Canada (HSFC) Lecture at the Canadian Cardiovascular Congress 2010.

26 Oct 2010

Atherosclerosis News and Research

Further Reading

PGxHealth presents results from studies using FAMILION genetic testing at 2010 AHA

TU/e researchers image stages of calcification process in atherosclerosis

Novel mechanism regulating circadian rhythm identified

Amarin reports $31.4 million cash balance for third quarter 2010

Positive results from XOMA 052 study in patients with uveitis of Behcet's disease

Researchers to determine levels of stroke risk in patients with narrowed brain arteries

BioInvent receives FDA IND clearance for BI-204 Phase II trial in cardiovascular disease

DHA protects brain tissue and promotes recovery in acute ischemic stroke

Multidetector CT helps pinpoint causes of ischemic stroke

Limiting inflammation can control accumulation of carotid atherosclerosis in RA patients

TRPM7 protein plays a key role in maintenance of magnesium homeostasis

Statin drugs do not benefit pediatric lupus patients

Spherix subsidiary awarded $469,479 grant under Patient Protection and Affordable Care Act

Immune Network to complete patient enrollment in Phase 2b imm01 trial for tuberculosis

Atrium completes enrollment in iCAST Atrium Registry Ultrasound Study

New findings pave way to improve early detection of ovarian cancer

Merck reports $342 million net income for 2010 third quarter

Stryker enters agreement to acquire assets of Neurovascular division of Boston Scientific

Archimedes launches AOA web application to help healthcare organizations

Prevention of vascular diseases needed to avoid tsunami of cases

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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