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Lab-on-a-chip designed to predict woman's risk of preterm birth

In the United States alone, a half million babies are born preterm; worldwide, the number is an estimated 15 million. Complications associated with preterm birth are the no. 1 cause of death for children under 5, and those who live often face a range of health problems.

13 Apr 2017

Prevention, not cure, may be key to stopping Alzheimer’s disease

It has been 111 years since Auguste D. became the first person described with what is now called Alzheimer's disease.

12 Apr 2017

Study reveals potential new therapeutic approach to tackle infection by Legionella bacteria

The precise mechanism used by Legionella bacteria to escape the body's defences has been unpicked in intricate detail and is described for the first time in the journal eLife.

11 Apr 2017

MIT engineers develop more sensitive approach to reveal ovarian tumors

Most ovarian cancer is diagnosed at such late stages that patients' survival rates are poor. However, if the cancer is detected earlier, five-year survival rates can be greater than 90 percent.

10 Apr 2017

Study of interactions between chemokines pinpoints potential targets for treatment of inflammation

Signal molecules called chemokines often work in tandem to recruit specific sets of immune cells to sites of tissue damage.

7 Apr 2017

Study identifies key mediator in learning process

The ability of the brain to respond and adapt to changes is scientifically called brain plasticity. This ability is the basis of all learning processes.

7 Apr 2017

New finding on key protein opens door to potential therapies for chronic illnesses

Scientists have determined unexpected characteristics of a key protein linked to blood pressure control and to nerve growth, pain control and heart tissue regeneration. The findings, published April 5 online in the journal Nature, opens doors to potential new therapies to control cardiovascular disease and pain.

6 Apr 2017

X-ray study sheds new light on promising drug target

Researchers hope to design a new generation of drugs against an array of deadly diseases. The task, however, is costly, arduous and often ineffective. One of the key challenges is understanding a particular class of proteins adorning cell surfaces, which are the targets of the majority of pharmaceutical drugs.

5 Apr 2017

New strategy in antimicrobial peptides holds promise for combating multi-drug resistant bacteria

In an article published recently in Plos One, researchers from INRS-Institut Armand-Frappier Research Centre reported a strategy that could lead to the discovery of new cationic antimicrobial peptides (CAMPs) with greatly enhanced antimicrobial properties.

5 Apr 2017

Research finding could set stage for potential development of new antimicrobial drugs

Research teams from the National Institutes of Health and abroad have identified the first inhibitor of an enzyme long thought to be a potential drug target for fighting disease-causing parasites and bacteria.

3 Apr 2017

Researchers use mathematical modeling to raise density of bones badly degraded by osteoporosis

They may seem rigid and set in their ways, but your bones are actually under constant construction and deconstruction. They give up their nutrient treasures (calcium) to the body and then rebuild in a constant give-and-take sort of rhythm.

29 Mar 2017

TSRI scientists develop novel method to analyze glycan shield on HIV’s glycoprotein

HIV is a master of disguise. The virus uses a shield of sugar molecules, called glycans, to hide from the immune system and block antibodies from attacking it.

28 Mar 2017

Researchers characterize ‘gold fingers’ using ion mobility mass spectrometry

Drugs containing gold have been used for centuries to treat conditions like rheumatoid arthritis. In addition, they might be effective against cancer and HIV.

28 Mar 2017

Neurology researchers on the hunt for biomarker signal for early detection of Alzheimer's disease

Around 100,000 Austrians suffer from Alzheimer's disease and 16,000 from Parkinson's. Experts estimate that, in view of the ageing population, these numbers are set to triple over the next 30 years.

27 Mar 2017

Researchers develop nanoparticle to deliver potential new drug to breast cancer cells

The research, a collaborative project between Queen's University Belfast and Ulster University, began at the Queen's Centre for Cancer Research and Cell Biology in 2014, and was led by Professor Mohamed El-Tanani.

24 Mar 2017

Postnova PN3621 MALS sets new standard for sensitive and precise multi-angle light scattering detection

The PN3621 MALS from Postnova Analytics sets a new standard for sensitive, precise and flexible Multi-Angle Light Scattering detection for Size Exclusion Chromatography (SEC) and Field Flow Fractionation (FFF) systems.

From Pittcon 24 Mar 2017

Research suggests novel strategy to target genetic anomaly in prostate cancers

New research suggests a novel strategy to target a genetic anomaly that occurs in half of all prostate cancers.

24 Mar 2017

Analysis of antibodies could be new tool for predicting prognosis and choosing therapy for RA patients

In rheumatoid arthritis, antibodies are formed that affect the inflammation in the joints. In an article published today in the journal Annals of the Rheumatic Diseases, researchers at Uppsala University show that antibodies against the cartilage protein collagen II are associated with a good prognosis.

23 Mar 2017

Scientists identify new toxic pathway for protein aggregates in ALS and FTLD

Led by professor Ludo Van Den Bosch, scientists from Belgium, the UK and the US have identified new processes that form protein "clumps" that are characteristic of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD).

17 Mar 2017

MPFI researchers develop new tool to study CaMKII kinetics in learning and memory

As we learn, the structure of individual neurons in our brains change to strengthen important connections and weaken less important ones, a process known as structural plasticity.

16 Mar 2017