Aging News and Research

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Senolytic agent ABT-263 mitigates GI cancer risk after radiation exposure

A new research paper was published by Aging (Aging-US) on January 8, 2025, in Volume 17, Issue 1, titled "Senolytic agent ABT-263 mitigates low- and high-LET radiation-induced gastrointestinal cancer development in Apc1638N/+ mice."

18 Feb 2025

Researchers discover direct feedback loop in brain circuit connecting memories and emotions

A newly identified part of a brain circuit mixes sensory information, memories, and emotions to tell whether things are familiar or new, and important or just "background noise."

18 Feb 2025

ImmuneLENS method provides new insights into cancer prognosis

The immune systems of cancer patients are highly disrupted, with those who have a higher number of immune cells in their blood having a better survival rate, finds a new study that uses a pioneering technique developed by researchers at UCL and the Francis Crick Institute.

18 Feb 2025

Iowa Medicaid sends $4M bills to two families grieving deaths of loved ones with disabilities

Collection agents for the state of Iowa have sent letters seeking millions of dollars from the estates of at least two people with disabilities who died after spending most of their lives in a state institution.

18 Feb 2025

Scientists pinpoint metabolic failure as the cause of muscle loss in aging

A multi-omics study reveals that impaired branched-chain amino acid (BCAA) catabolism is a key driver of sarcopenia, suggesting it as a potential therapeutic target.

17 Feb 2025

Peristaltic pumping motion found to trigger amyloid formation

Researchers from Osaka University find that peristaltic pump action and high shear flow forces promote amyloid nucleation.

17 Feb 2025

Researchers develop a way to treat muscular atrophy using regenerative medicine

Researchers from Tokyo Metropolitan University have developed a way to treat ageing-related muscular atrophy using regenerative medicine.

17 Feb 2025

ICHOM develops standard dataset that defines heart valve disease outcomes

The International Consortium for Health Outcomes Measurement (ICHOM) has developed a globally inclusive standard dataset of 16 patient-centered outcome measures for people with heart valve disease, regardless of treatment (surgical or transcatheter procedure), according to a new report published today in the American Heart Association's journal Circulation: Cardiovascular Quality & Outcomes.

17 Feb 2025

Obesity and cognition: Surprising study links higher BMI to better memory

Higher BMI in early adulthood and midlife is linked to better memory performance, particularly in men and Black Americans, challenging traditional views on obesity and cognition.

16 Feb 2025

Prozac's surprising immune-boosting effects could lead to new treatments for sepsis

Antidepressants like Prozac are commonly prescribed to treat mental health disorders, but new research suggests they could also protect against serious infections and life-threatening sepsis.

14 Feb 2025

New discovery on mitochondrial protein could transform Charcot-Marie-Tooth treatment

Researchers from Cologne, Bochum, Padova and Angers have discovered a novel connection between mitochondrial function, protein quality control and cellular health, whose failure could be the leading cause in the currently incurable neurological disease Charcot-Marie-Tooth (CMT).

14 Feb 2025

As states mull Medicaid work requirements, two scale theirs back

President Donald Trump's return to the White House sent a clear signal about Medicaid to Republicans across the country: Requiring enrollees to prove they are working, volunteering, or going to school is back on the table.

14 Feb 2025

New insight into gut stem cell aging

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular signal-regulated kinase (ERK)/mitogen-activated protein kinase (MAPK) signaling is essential for preserving the intestinal stem cell population during aging.

13 Feb 2025

Rethinking red meat: Are dietary guidelines missing the bigger picture?

Research highlights the critical role of red meat in providing essential nutrients like iron, zinc, and B12, particularly for vulnerable populations, while questioning the low-certainty evidence linking it to chronic diseases. It urges policymakers to balance health, environmental, and economic factors when considering dietary guidelines.

13 Feb 2025

New atlas reveals aging’s impact on breast tissue and cancer risk

Aging is a privilege, but it also brings risks-including an increased likelihood of developing age-related diseases including cancer.

13 Feb 2025

Eating behavior associated with pelvic floor disorder symptoms in middle-aged women

According to a recent study conducted at the University of Jyväskylä, Finland, eating behavior is associated with symptoms of pelvic floor disorders in middle-aged women.

13 Feb 2025

Older Americans find purpose and well-being in work, despite health barriers

Research shows older adults working past 65 experience significant health benefits and financial stability, highlighting the importance of supportive policies.

13 Feb 2025

Natural supplement shows promise in treating heart disease

Heart transplant is a scary and serious surgery with high cost, but for patients with heart failure it can be the only option for cure.

13 Feb 2025

Brain aging linked to neuronal hyperactivation, not decline, study finds

A study of nematodes by researchers at Nagoya University in Japan has found that aging-related decline in brain function is caused by the excessive activation of certain neurons over time, rather than a decline in neuronal activity.

13 Feb 2025

Study connects loneliness and social isolation to non-alcoholic fatty liver disease risk

Loneliness and social isolation have been linked to an elevated risk of non-alcoholic fatty liver disease (NAFLD), according to a groundbreaking study conducted by researchers from Central South University and the Army Medical University in China, in collaboration with the Karolinska Institutet in Sweden.

12 Feb 2025