Proliferation News and Research

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Leaking components from broken muscle fibers activate 'satellite' muscle stem cells

While building a muscle damage model in a cultured system, a research collaboration between Kumamoto University and Nagasaki University in Japan has found that components leaking from broken muscle fibers activate "satellite" muscle stem cells.

12 Oct 2020

Study elucidates the role of ERβ in growth of skeletal muscle in female mice

Researchers at Kumamoto University, Japan generated mice lacking the estrogen receptor beta (ERβ) gene, both fiber-specific and muscle stem cell-specific, which resulted in abnormalities in the growth and regeneration of skeletal muscle in female mice.

12 Oct 2020

Researchers identify new mechanism underlying the progression of FAP-associated Desmoid tumor

Volume 11, Issue 26 of Oncotarget reported that in this study the authors studied the differences in mi RNA expression between sporadic and FAP-associated Desmoid tumors using microarray confirmed by quantitative PCR.

12 Oct 2020

Scientists discern molecular mechanisms underlying plant parasitism, cross-species grafting

Using the model Orobanchaceae parasitic plant Phtheirospermum japonicum, scientists from Nagoya University and other research institutes from Japan have discerned the molecular mechanisms underlying plant parasitism and cross-species grafting, pinpointing enzyme β-1,4-glucanase (GH9B3) as an important contributor to both phenomena.

12 Oct 2020

Rapid and sensitive detection of SARS-CoV-2 with functionalized magnetic nanoparticles

A recent study published on the preprint server arXiv in October 2020 shows the potential for using functionalized magnetic nanoparticles to detect the presence of the virus in a sample.

11 Oct 2020

Exciting findings on CD8 T cell response in recovered COVID patients

An international team of scientists has identified novel T cell-recognized epitopes spanning different proteins of severe acute respiratory syndrome coronavirus 2 in COVID-19 recovered patients. The scientists have also revealed phenotypical characteristics of the T cell population.

11 Oct 2020

Proteolytic cleavage of nucleocapsid helps SARS-CoV-2 evade host immune responses

A team of scientists of the University of Oxford reveals that the nucleocapsid protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) undergoes autoproteolysis, and that resulting products can escape the host immune responses and facilitate viral proliferation. The study is currently available on the bioRxiv preprint server.

7 Oct 2020

Amniotic fluid stem cells may lead to better treatment for ischemic stroke

A study released today in STEM CELLS Translational Medicine points the way to a possible new avenue of treatment for ischemic stroke.

7 Oct 2020

Theoretical model explains biological phenomena that keep bacteria in shape

Fat bacteria? Skinny bacteria? From our perspective on high, they all seem to be about the same size. In fact, they are.Precisely why has been an open question, according to Rice University chemist Anatoly Kolomeisky, who now has a theory.

7 Oct 2020

New imaging technique can replace invasive tissue biopsies in cancer treatment

Imaging techniques could replace the need for invasive tissue biopsies in helping rapidly determine whether cancer treatments are working effectively, according to researchers at the University of Cambridge.

7 Oct 2020

Researchers develop new testing platform for breast cancer cells

A Purdue University team has developed a novel testing platform to evaluate how breast cancer cells respond to the recurrent stretching that occurs in the lungs during breathing.

6 Oct 2020

Severe lymphatic disorder reversed through genetic sequencing and targeted treatment

Through genetic sequencing and targeted treatment, researchers from Children's Hospital of Philadelphia have resolved a severe lymphatic disorder in a young woman with kaposiform lymphangiomatosis (KLA), a complex and rare disorder that causes lymphatic vessels around the heart and lung to leak fluid, causing breathing difficulties, infections, and often death.

5 Oct 2020

Potential drug treatment for AXL-low expressing EGFR-mutated lung cancer

Researchers at Kanazawa University report in Nature Communications the mechanism making some lung-cancer patients resistant to the drug osimertinib.

5 Oct 2020

Another study finds cross-reactivity T cell responses against SARS-CoV-2

Using ELISpot and proliferation assays, researchers show strong responses in SARS-CoV-2 infected patients, but not so much in negative samples. However, there may be cross-reactive T cell responses from other human coronaviruses.

5 Oct 2020

Lung tissue in fatal COVID-19 shows broad cell tropism and extensive damage

In a recent preprint paper published on the medRxiv server, researchers demonstrated their investigation of fatal COVID-19 patients to assess infection in various cell types and the extent of damage it caused to the lung tissues.

30 Sep 2020

Scientists identify key molecules that mediate radioresistance in aggressive brain cancer

Scientists have identified key molecules that mediate radioresistance in glioblastoma multiforme; these molecules are a potential target for the treatment of this brain cancer.

30 Sep 2020

FUJIFILM Irvine Scientific to exclusively distribute chemically defined substrate for stem cell culture

FUJIFILM Irvine Scientific today announced that it has become the exclusive, worldwide distributor of cellnest®, a recombinant peptide attachment substrate.

From FUJIFILM Irvine Scientific 30 Sep 2020

Researchers report promising preclinical findings for a prototype of vascular graft

In a proof-of-concept study, North Carolina State University researchers reported promising preclinical findings for a prototype of a vascular graft designed as a replacement for a damaged or blocked coronary artery, which supplies blood to the heart.

30 Sep 2020

Induction of acute senescence may be a necessary process in hemorrhagic shock

It's called senescence, when stressed cells can no longer divide to make new cells, and it's considered a factor in aging and in some diseases.

29 Sep 2020

Study finds link between screen time, dietary patterns and various health behaviors

The era of the television brought with it the TV dinner -- a fast, convenient meal that, while nutritionally questionable, meant the whole family could gather together on the sofa to enjoy "The Ed Sullivan Show" and eat their Swanson Salisbury steak, too.

28 Sep 2020

Proliferation News and Research

Leaking components from broken muscle fibers activate 'satellite' muscle stem cells

Study elucidates the role of ERβ in growth of skeletal muscle in female mice

Researchers identify new mechanism underlying the progression of FAP-associated Desmoid tumor

Scientists discern molecular mechanisms underlying plant parasitism, cross-species grafting

Rapid and sensitive detection of SARS-CoV-2 with functionalized magnetic nanoparticles

Exciting findings on CD8 T cell response in recovered COVID patients

Proteolytic cleavage of nucleocapsid helps SARS-CoV-2 evade host immune responses

Amniotic fluid stem cells may lead to better treatment for ischemic stroke

Theoretical model explains biological phenomena that keep bacteria in shape

New imaging technique can replace invasive tissue biopsies in cancer treatment

Researchers develop new testing platform for breast cancer cells

Severe lymphatic disorder reversed through genetic sequencing and targeted treatment

Potential drug treatment for AXL-low expressing EGFR-mutated lung cancer

Another study finds cross-reactivity T cell responses against SARS-CoV-2

Lung tissue in fatal COVID-19 shows broad cell tropism and extensive damage

Scientists identify key molecules that mediate radioresistance in aggressive brain cancer

FUJIFILM Irvine Scientific to exclusively distribute chemically defined substrate for stem cell culture

Researchers report promising preclinical findings for a prototype of vascular graft

Induction of acute senescence may be a necessary process in hemorrhagic shock

Study finds link between screen time, dietary patterns and various health behaviors

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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