Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Genta initiates new dose-ranging study of tesetaxel drug

Genta Incorporated announced that the Company has initiated a new dose-ranging study of tesetaxel, the Company’s novel oral tubulin inhibitor, using a weekly dosing regimen. Tesetaxel -- a late Phase 2 oncology product -- is the leading oral taxane currently in clinical development.

26 Feb 2010

Kinex Pharmaceuticals announces KX2-391 Phase 2 safety and efficacy clinical trial in men with CRPC

Kinex Pharmaceuticals opened a Phase 2 clinical trial to evaluate the safety and efficacy of KX2-391 in patients with bone-metastatic, castrate-resistant prostate cancer (CRPC) who have not had prior chemotherapy.

25 Feb 2010

Regulus Therapeutics, GSK announce new collaboration on microRNA therapeutics targeting microRNA-122

Regulus Therapeutics Inc. today announced the establishment of a new collaboration with GlaxoSmithKline (GSK) to develop and commercialize microRNA therapeutics targeting microRNA-122 in all fields with Hepatitis C Viral infection (HCV) as the lead indication. Under the terms of the new collaboration, Regulus will receive additional upfront and early-stage milestone payments with the potential to earn more than $150 million in miR-122-related combined payments, and tiered royalties up to double digits on worldwide sales of products.

25 Feb 2010

Interventional radiologists to highlight scientific advances, new discoveries at 35th Annual Scientific Meeting

Interventional radiologists-minimally invasive specialists-will share scientific advances and new discoveries in treating a host of diseases at the Society of Interventional Radiology's 35th Annual Scientific Meeting March 13󈝾 at the Tampa Convention Center, Tampa, Fla. This year's meeting theme is "IR Innovation"-one that celebrates the remarkable inventiveness of interventional radiologists.

25 Feb 2010

OncoGenex Pharmaceuticals receives CHMP advice on OGX-011 development plan in treatment of mCRPC

OncoGenex Pharmaceuticals announced today that it has received written, scientific advice from the European Medicines Agency (EMA) on the company's development plan for OGX-011 (also known as custirsen) for the treatment of men with metastatic castrate-resistant prostate cancer (mCRPC). The input received from the Committee for Medicinal Products for Human Use (CHMP) at the EMA was in overall agreement with OncoGenex's development plan regarding the proposed preclinical studies and both the study designs and analyses for the Phase III trials.

25 Feb 2010

Semafore Pharmaceuticals awarded U.S. patent covering PI-3 kinase inhibitor prodrugs

Semafore Pharmaceuticals today announced today announced the United States Patent and Trademark Office (PTO) has issued United States Patent Number 7,662,977 entitled “PI-3 Kinase Inhibitor Prodrugs.” This composition of matter patent covers a genus of novel compounds that includes SF1126, Semafore’s clinical stage, small molecule inhibitor of phosphoinositide-3-kinase (PI3K) and mammalian target of rapamycin (mTOR), two key members of the PI3K signaling pathway that is vital to several essential biological processes, such as cell proliferation and survival.

25 Feb 2010

NIPTRC and partners announce development of new imaging process for proton beam therapy in cancer

Scientists and researchers from the Northern Illinois Proton Treatment and Research Center (NIPTRC) and Northern Illinois University along with their partners are developing a new imaging process using a proton beam that they believe will be a major medical breakthrough in the delivery of proton beam therapy for cancer patients.

25 Feb 2010

ESMO conference on sarcoma and gastrointestinal stromal tumour

More should be done across Europe to ensure that people with rare forms of cancer are not denied access to the best possible treatment, say the organizers of a major European cancer conference to be held in Milan on 9 and 10 March 2010.

25 Feb 2010

US Oncology acquires CURE Media Group and NexCura

US Oncology, Inc., the premier cancer care services organization supporting the nation's largest cancer treatment and research network dedicated to advancing the quality and cost-effectiveness of cancer care in America, announced today that it has acquired Dallas-based CURE Media Group and Seattle-based NexCura. These two companies serve as an important piece of the overall strategy for US Oncology to expand the availability of integrated and personalized information and resources on specific diseases and treatments to cancer patients in America.

25 Feb 2010

ESMO Conference to address issues relating to sarcoma and GIST

25 Feb 2010

WSU Boonshoft School of Medicine and Miami Valley Hospital form new neuroscience institute

Wright State University Boonshoft School of Medicine and Miami Valley Hospital announced today the formation of the Wright State University & Premier Health Partners Neuroscience Institute to speed the transfer of research discoveries from bench to bedside, improving the diagnosis and treatment of neurological disorders such as stroke. Ohio Governor Ted Strickland and Chancellor of the Ohio Board of Regents Eric Fingerhut joined Wright State University and Miami Valley Hospital officials in making the announcement.

25 Feb 2010

Study examines how individuals utilize benefits and services under Medicare program

Findings released today and detailed in the analysis Low Consumption and Higher Medicare Cost: Consumption Clusters in a Medicare Fee-for-Service Population, examine how individuals utilize benefits and services under the Medicare program.

25 Feb 2010

Asymptomatic pancreatic cyst treatment: UCLA-Veterans Affairs research team develops evaluation tool

As a result of improved imaging technology, pancreatic cysts are increasingly diagnosed in asymptomatic individuals who undergo scans for other reasons. And while most of these cysts follow a benign course, a small but significant number are either malignant at the time of diagnosis or have the potential to develop into pancreatic cancer during a patient's lifetime.

25 Feb 2010

Philanthropic organizations fund for cancer research studies

Eight philanthropic organizations and families in the Charlotte region have joined forces to create the "Carolinas Kids Cancer Research Coalition," which is providing funding for the introduction of Phase I and Phase II clinical trials by the Pediatric Hematology and Oncology Center at Levine Children's Hospital (LCH).

25 Feb 2010

Advanced ovarian cancer: Avastin-chemotherapy combination followed by Avastin alone improves PFS

Genentech, Inc., a wholly owned member of the Roche Group, today announced that a Phase III study showed the combination of Avastin® (bevacizumab) and chemotherapy followed by maintenance use of Avastin alone increased the time women with previously untreated advanced ovarian cancer lived without the disease worsening (progression-free survival or PFS), compared to chemotherapy alone. A preliminary assessment of safety noted adverse events previously observed in pivotal trials of Avastin.

25 Feb 2010

EpiCept provides business update and fourth-quarter financial highlights

EpiCept Corporation today announced operating and financial results for the fourth quarter and year ended December 31, 2009, and provided an update on Ceplene® and several of the Company’s key product candidates.

25 Feb 2010

Biochemical link between misery and death discovered

In ongoing work to identify how genes interact with social environments to impact human health, UCLA researchers have discovered what they describe as a biochemical link between misery and death. In addition, they found a specific genetic variation in some individuals that seems to disconnect that link, rendering them more biologically resilient in the face of adversity.

25 Feb 2010

Researchers develop evaluation tool to help guide asymptomatic pancreatic cyst treatment

25 Feb 2010

Researchers to test Radio-embolisation technique in patients with bowel cancer

Cancer Research UK this week launches a new trial for patients with bowel cancer that has spread to the liver to see whether a new radiotherapy treatment technique is more effective than standard chemotherapy.

24 Feb 2010

Five Prime Therapeutics receives milestone payment for selection of therapeutic program

Five Prime Therapeutics, Inc. today announced it received a milestone payment from Centocor Research & Development, Inc. for the selection of a therapeutic that will be pursued for immunology-related indications. Under the collaboration, FivePrime identified multiple potential therapeutic targets through screening its comprehensive proprietary protein library in cell-based assays that were focused on therapeutic pathways underlying specific immune and inflammatory disorders.

24 Feb 2010

Oncology News and Research

Further Reading

Genta initiates new dose-ranging study of tesetaxel drug

Kinex Pharmaceuticals announces KX2-391 Phase 2 safety and efficacy clinical trial in men with CRPC

Regulus Therapeutics, GSK announce new collaboration on microRNA therapeutics targeting microRNA-122

Interventional radiologists to highlight scientific advances, new discoveries at 35th Annual Scientific Meeting

OncoGenex Pharmaceuticals receives CHMP advice on OGX-011 development plan in treatment of mCRPC

Semafore Pharmaceuticals awarded U.S. patent covering PI-3 kinase inhibitor prodrugs

NIPTRC and partners announce development of new imaging process for proton beam therapy in cancer

ESMO conference on sarcoma and gastrointestinal stromal tumour

US Oncology acquires CURE Media Group and NexCura

ESMO Conference to address issues relating to sarcoma and GIST

WSU Boonshoft School of Medicine and Miami Valley Hospital form new neuroscience institute

Study examines how individuals utilize benefits and services under Medicare program

Asymptomatic pancreatic cyst treatment: UCLA-Veterans Affairs research team develops evaluation tool

Philanthropic organizations fund for cancer research studies

Advanced ovarian cancer: Avastin-chemotherapy combination followed by Avastin alone improves PFS

EpiCept provides business update and fourth-quarter financial highlights

Biochemical link between misery and death discovered

Researchers develop evaluation tool to help guide asymptomatic pancreatic cyst treatment

Researchers to test Radio-embolisation technique in patients with bowel cancer

Five Prime Therapeutics receives milestone payment for selection of therapeutic program

Event guide: The 9th DDR Inhibitors Summit 2026 eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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