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Stress and obesity found to fuel early pancreatic cancer growth

A new study led by UCLA investigators suggests that chronic stress and an unhealthy diet may work together to fuel the early development of pancreatic cancer, shedding light on how lifestyle factors contribute to one of the deadliest malignancies.

10 Mar 2025

Scientists discover key molecular switch for blood stem cell regeneration

A single molecular switch is essential for blood stem cells to enter an activated, regenerative state in which they produce new blood cells, according to a preclinical study led by Weill Cornell Medicine investigators.

10 Mar 2025

New stem cell-based vascular grafts could revolutionize cardiac surgery

Scientists at the Wisconsin National Primate Research Center (WNPRC) and the Morgridge Institute for Research at the University of Wisconsin–Madison have been at the forefront of stem cell research and regenerative biology since James Thomson isolated the first human embryonic stem cell in 1998.

10 Mar 2025

Exploring the causal links among immune cells, inflammatory proteins, and aortic dissection

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Aortic dissection is a life-threatening condition with complex immunological underpinnings.

10 Mar 2025

MRNA vaccines, once a Trump boast, now face attacks from some in GOP

Researchers racing to develop bird flu vaccines for humans have turned to a cutting-edge technology that enabled the rapid development of lifesaving covid shots.

10 Mar 2025

How to pick healthier gluten-free bread

Gluten-free (GF) breads and flours often contain less natural fiber and more fat than gluten-containing counterparts, with added psyllium or gums boosting fiber at the cost of higher saturated fats. Researchers urge better formulation to match GF diets’ nutritional quality to traditional options.

9 Mar 2025

Long-term NSAID use may lower dementia risk

Long-term NSAID use reduces dementia risk, particularly in those without the APOE-ε4 gene, highlighting the importance of sustained anti-inflammatory treatment over dosage levels.

9 Mar 2025

Understanding the role of LSD1 in cellular processes and disease

A new review highlights the pivotal role of LSD1 (lysine-specific demethylase 1) in regulating critical cellular processes and its implications for human diseases.

8 Mar 2025

Circular RNA plays key role in cancer biology and therapy

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies.

8 Mar 2025

Ubiquitination plays a key role in cancer stem cell function and treatment resistance

This review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), shedding light on potential therapeutic targets for combating tumor progression, recurrence, and drug resistance.

8 Mar 2025

Groundbreaking discovery in cardiac regeneration offers new hope for heart failure treatment

Researchers in the Michael E. DeBakey Department of Surgery at Baylor College of Medicine, the QIMR Berghofer Medical Research Institute in Brisbane, Australia, and collaborating institutions report a groundbreaking discovery in cardiac regeneration that offers new hope for the treatment of ischemic heart failure.

7 Mar 2025

Exosome-mediated siRNA delivery targets antibiotic resistance in bacteria

Multidrug-resistant bacteria pose a major threat to human health. Manipulation of bacterial genes at the transcriptional level is a potential strategy to fight antibiotic-resistant bacterial infections by silencing their resistance genes.

7 Mar 2025

New algorithm enhances prediction of disordered protein structures

The intrinsically disordered proteins (IDPs) do not attain a stable secondary or tertiary structure and rapidly change their conformation, making structure prediction particularly challenging.

7 Mar 2025

TRIMTECH Therapeutics raises $31M seed funding to advance targeted protein degradation pipeline for treatment of neurodegenerative diseases

TRIMTECH Therapeutics raises $31M to enhance its TRIMTAC platform, targeting protein aggregates in neurodegenerative diseases for improved therapeutic outcomes.

From TRIMTECH Therapeutics 7 Mar 2025

Study uncovers how transposons use telomeres for survival in bacteria

Transposons, or "jumping genes" – DNA segments that can move from one part of the genome to another – are key to bacterial evolution and the development of antibiotic resistance.

7 Mar 2025

New brain mapping technique identifies cells vulnerable to Alzheimer's disease

Researchers from The University of Texas at Arlington and the University of California–San Francisco have used a new brain-mapping technique to identify memory-related brain cells vulnerable to protein buildup, a key factor in the development of Alzheimer's disease, an incurable, progressive brain disorder that slowly destroys memory and thinking skills.

6 Mar 2025

Partial gland cryoablation offers long-term success for prostate cancer patients

A five-year study on men that had just the cancerous portion of their prostate glands destroyed shows that the procedure averted cancer recurrence in most patients while preserving urinary and sexual function.

6 Mar 2025

Asah1 gene plays key role in preventing progression of nonalcoholic fatty liver disease

Investigators have found that the gene Asah1 plays a crucial protective role in preventing the progression of nonalcoholic fatty liver diseases (NAFLD) into more severe forms of liver disease by regulating hepatic lipid homeostasis and cellular maintenance processes.

6 Mar 2025

Researchers discover why scleroderma affects women more than men

Two new studies led by researchers at Hospital for Special Surgery (HSS) have uncovered key biological mechanisms driving systemic sclerosis (SSc), or scleroderma – a rare and often devastating autoimmune disease that causes fibrosis (tissue hardening) and inflammation.

6 Mar 2025

Study suggests boosting brain's immune cells could improve Alzheimer's treatment

For more than three decades, scientists have been racing to stop Alzheimer's disease by removing amyloid beta plaques - sticky clumps of toxic protein that accumulate in the brain.

6 Mar 2025