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Rare gene mutation gives rise to low sensitivity to pain

Researchers at University College London have identified a rare gene mutation in an Italian family who have little sensitivity to some forms of pain. Chronic pain caused by conditions such as lower back pain and osteoarthritis is one of the most prominent causes of disability worldwide, as assessed by the Global Burden of Disease reviews.

15 Dec 2017

Researchers examine link between tumor mutational burden and response to immune checkpoint therapy

Predicting how patients will respond to anti-cancer therapies can be vital in informing clinical decisions and improving treatment outcome.

15 Dec 2017

APS Scientific Summit explores biopsychosocial mechanisms that influence pain

Understanding Pain Mechanisms is the theme of the American Pain Society's Scientific Summit, www.americanpainsociety.org, March 4-6 at the Disneyland Hotel in Anaheim.

15 Dec 2017

Researchers team up to identify vulnerabilities of lethal parasite

An estimated 100 million people around the world are infected with Strongyloides stercoralis, a parasitic nematode, yet it's likely that many don't know it.

15 Dec 2017

Fusion gene may be found in cSCC lesions on skin exposed frequently to the sun

A fusion gene is a single composite gene that is the result of the combination of two formerly independent genes. Researchers from Kumamoto University, Japan have determined that a particular fusion gene has a tendency to be found in cutaneous squamous cell carcinoma (cSCC) lesions on skin exposed frequently to the sun.

14 Dec 2017

Outpatient total knee replacement surgery linked to higher rates of complications

Some complications are more common when total knee replacement surgery is done as an outpatient or same-day procedure, reports a study in the December 6, 2017 issue of The Journal of Bone & Joint Surgery. The journal is published in partnership with Wolters Kluwer.

14 Dec 2017

Relieving Symptoms of Cystic Fibrosis with Exercise

We know that exercise is beneficial in helping someone to maintain their lung function, stay strong and active and maintain a good quality of life. We also know that exercise can complement ‘airway clearance techniques’ – breathing exercises prescribed by physiotherapists to help clear the lungs of mucus.

14 Dec 2017

Study finds social stigma as barrier to successful treatment of children with HIV in Ethiopia

The social stigma surrounding HIV is still strong in many parts of the world. Children living with HIV in Ethiopia are at high risk of receiving inadequate treatment - or no treatment at all - on account of deeply rooted prejudice.

14 Dec 2017

Radiation therapy can be used to treat patients with life-threatening heart rhythm

Radiation therapy often is used to treat cancer patients. Now, doctors at Washington University School of Medicine in St. Louis have shown that radiation therapy - aimed directly at the heart - can be used to treat patients with a life-threatening heart rhythm.

14 Dec 2017

Groundbreaking gene therapy trial brings cure for hemophilia closer

A 'cure' for hemophilia is one step closer, following results of a groundbreaking gene therapy trial led by the NHS in London.

14 Dec 2017

Targeted lung cancer treatments may benefit smokers and non-smokers alike

Smokers are less likely than non-smokers to have lung cancers caused by targetable genetic changes. But a study published this week in the journal Clinical Cancer Research shows that when they do, smokers benefit just as much as non-smokers from targeted treatments.

13 Dec 2017

Transfusion dependence reduces access to high-quality end-of-life care for leukemia patients

For patients with advanced leukemia, access to high-quality end-of-life care appears to be reduced in those dependent on blood transfusions, according to a new study being presented during the 59th American Society of Hematology Annual Meeting and Exposition in Atlanta.

13 Dec 2017

Survey shows prevalence of diarrhea in people living with HIV

Napo Pharmaceuticals, Inc., a human health company developing and commercializing novel gastrointestinal prescription products from plants used traditionally in rainforest areas, and a wholly-owned subsidiary of Jaguar Health, Inc., today released the results of a survey of 350 people living with HIV and AIDS on "Talking to Your Doctor About Symptoms".

13 Dec 2017

Performing surgery on virtual patient could provide valuable insight into consequences

Is surgery the best option or not, in the case of cancer in the head and neck? As the consequences for speaking and swallowing may be severe, some way of predicting these consequences would help in the decision-making.

13 Dec 2017

Researchers use RNA nanotechnology to program exosomes for delivering effective cancer therapies

A new study shows that attaching antibody-like RNA nanoparticles to microvesicles can deliver effective RNA therapeutics such as small interfering RNA specifically to cancer cells.

13 Dec 2017

Study finds barriers to stem cell transplant use among multiple myeloma patients from minority groups

A study by researchers at Mayo Clinic's campus in Jacksonville, Florida has found that barriers to patients receiving stem cell therapy as part of their treatment for multiple myeloma include income, education, insurance status and access to care at an academic center or facility that treats a high volume of patients.

13 Dec 2017

Researchers take step toward using man-made nanoscale compounds to fight cancer

Researchers in Sweden have succeeded in taking the next step toward using man-made nanoscale compounds in the fight against cancer.

13 Dec 2017

Specialized physiotherapy provides many benefits for patients with Parkinson’s disease

Specialized ParkinsonNet physiotherapy leads to better care at lower costs. This is the conclusion of large-scale research conducted by the CZ healthcare insurance company and Radboudumc, who studied the medical claims declarations of over four thousand people with Parkinson's disease for a period of three years.

13 Dec 2017

New treatments may soon transform lives of people with hearing loss

Charity Action on Hearing Loss has released its latest update on the progress that it is making to accelerate the development of technology and treatments for people living with deafness, tinnitus and hearing loss.

13 Dec 2017

DePuy Synthes releases Continuous Compression Implants to improve outcomes of foot and ankle procedures

DePuy Synthes today announced the availability of Continuous Compression Implants to health care providers across Europe, the Middle East and Africa. The implants are designed to provide continuous, active compression throughout the healing process to treat a variety of reconstructive foot and ankle procedures, and provide more solutions for our patients and customers.

From DePuy Synthes 13 Dec 2017

Therapy News and Research

Rare gene mutation gives rise to low sensitivity to pain

Researchers examine link between tumor mutational burden and response to immune checkpoint therapy

APS Scientific Summit explores biopsychosocial mechanisms that influence pain

Researchers team up to identify vulnerabilities of lethal parasite

Fusion gene may be found in cSCC lesions on skin exposed frequently to the sun

Outpatient total knee replacement surgery linked to higher rates of complications

Relieving Symptoms of Cystic Fibrosis with Exercise

Study finds social stigma as barrier to successful treatment of children with HIV in Ethiopia

Radiation therapy can be used to treat patients with life-threatening heart rhythm

Groundbreaking gene therapy trial brings cure for hemophilia closer

Targeted lung cancer treatments may benefit smokers and non-smokers alike

Transfusion dependence reduces access to high-quality end-of-life care for leukemia patients

Survey shows prevalence of diarrhea in people living with HIV

Performing surgery on virtual patient could provide valuable insight into consequences

Researchers use RNA nanotechnology to program exosomes for delivering effective cancer therapies

Study finds barriers to stem cell transplant use among multiple myeloma patients from minority groups

Researchers take step toward using man-made nanoscale compounds to fight cancer

Specialized physiotherapy provides many benefits for patients with Parkinson’s disease

New treatments may soon transform lives of people with hearing loss

DePuy Synthes releases Continuous Compression Implants to improve outcomes of foot and ankle procedures

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