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New Phase 1 study evaluates prime/boost HIV-1 vaccine formulated with combinations of adjuvants

A new Phase 1 vaccine study began today that will evaluate experimental prime/boost HIV-1 vaccine regimens formulated with combinations of different adjuvants, including one from the Army Liposome Formulation (ALF) family of adjuvants developed by scientists with the U.S. Military HIV Research Program at the Walter Reed Army Institute of Research.

15 Mar 2021

48Hour Discovery and Merck join hands to accelerate drug development

48Hour Discovery and CQDM are proud to announced that the company has been awarded $800,000 for peptide drug discovery using its patented drug discovery platform.

15 Mar 2021

The role of nanotechnology in the fight against COVID-19

Appearing in the journal Nanomedicine, the review summarized all the exciting advances made using diverse nanomaterials (polymeric, inorganic self-assembling materials and peptide-based) towards COVID-19 prevention, diagnosis and therapy.

15 Mar 2021

WHA’s president outlines plans to improve treatments for patients with hepatitis

Danjuma Adda, a Nigerian public health expert, became the president-elect of the World Hepatitis Alliance (WHA) in November last year. He is the first African to hold the position.

15 Mar 2021

Neutralizing antibodies induced by COVID-19 vaccines less effective against new variants

SARS-CoV-2, the virus that causes COVID-19, has mutated throughout the pandemic. New variants of the virus have arisen throughout the world, including variants that might possess increased ability to spread or evade the immune system.

13 Mar 2021

SARS-CoV-2 did not change much when it jumped from bats to human hosts

How much did SARS-CoV-2 need to change in order to adapt to its new human host? In a research article published in the open access journal PLOS Biology Oscar MacLean, Spyros Lytras at the University of Glasgow, and colleagues, show that since December 2019 and for the first 11 months of the SARS-CoV-2 pandemic there has been very little 'important' genetic change observed in the hundreds of thousands of sequenced virus genomes.

13 Mar 2021

Study shows link between financial strain, homelessness and severe mental illness

Financial strains like debt or unemployment are significant risk factors for becoming homeless, and even help to explain increased risk of homelessness associated with severe mental illness, reports a study in a supplement to the April issue of Medical Care.

13 Mar 2021

Scientists increase potency of HIV-1 antibody, identify new ways to develop vaccines

Much like coronavirus, circulating HIV-1 viruses mutate into diverse variants that pose challenges for scientists developing vaccines to protect people from HIV/AIDS.

12 Mar 2021

High obesity rates in Southern states magnify Covid threat

In January, as Mississippi health officials planned for their incoming shipments of covid-19 vaccine, they assessed the state's most vulnerable: health care workers, of course, and elderly people in nursing homes.

11 Mar 2021

Researchers shed light on T-cell receptor activation in response to infection

Immune cells specialize to ensure the most efficient defense against viruses and other pathogens. Researchers at the University of Basel have shed light on this specialization of T cells and shown that it occurs differently in the context of an acute and a chronic infection.

10 Mar 2021

Neutralizing antibodies may be evolving to keep up with SARS-CoV-2 mutations

Viruses evolve under increased pressure, and new research from The Rockefeller University and University of Massachusetts Medical School in the U.S. suggests our antibodies can as well.

10 Mar 2021

Home delivery of HIV medicines could increase ART adherence, viral suppression

Home delivery of HIV medicines in South Africa significantly increased viral suppression compared to those who received clinical care, according to a study by researchers at the University of Washington School of Medicine.

10 Mar 2021

Inflammation linked to intensity of tobacco smoking among HIV-positive people

Inflammation in the body has been linked to the intensity of tobacco smoking among people with HIV, according to a team of University of Massachusetts Amherst researchers.

8 Mar 2021

Biden’s criticism of Trump team’s vaccine contracts is a stretch

During a March 2 news conference on the covid-19 pandemic, President Joe Biden claimed that former President Donald Trump's administration did not ensure there would be enough vaccines for the American public.

8 Mar 2021

Novavax COVID-19 vaccine shows efficacy against South African SARS-CoV-2 variant

Researchers in the United States and South Africa report that the NVX-CoV2373 vaccine from Novavax has proved effective at preventing coronavirus disease (COVID-19) caused by the B.1.351 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has recently emerged in South Africa.

4 Mar 2021

Innovative cancer treatment effective in combating fungal infection in vitro and in mice

An innovative cell-based treatment for cancer has been found promising for the control of infections caused by fungi.

4 Mar 2021

Study demonstrates long-term neuropsychological consequences following SARS-CoV-2 infection

The study, published in the pre-print server medRxiv, demonstrates the presence of long-lasting neuropsychological sequelae after COVID-19, regardless of the respiratory disease's severity.

2 Mar 2021

New computer algorithm offers a path toward pan-influenza and coronavirus vaccine

A novel computer algorithm that could create a broadly reactive influenza vaccine for swine flu also offers a path toward a pan-influenza vaccine and possibly a pan-coronavirus vaccine as well, according to a new paper published in Nature Communications.

2 Mar 2021

Experimental therapy delays viral rebound in SHIV-infected macaques

A recent preclinical study by U.S. Military HIV Research Program (MHRP) researchers showed that an experimental therapy combining a TLR7 agonist and two broadly neutralizing antibodies delayed viral rebound in SHIV-infected macaques after antiretroviral therapy (ART) interruption.

2 Mar 2021

Protein kinase inhibitors could help treat immunodeficiency in HIV patients

HIV infections are treated with antiviral drugs which effectively prevent the disease from developing. While pharmacological HIV therapy has advanced considerably, the virus cannot be entirely eliminated from the body with currently available drugs.

1 Mar 2021

HIV News and Research

New Phase 1 study evaluates prime/boost HIV-1 vaccine formulated with combinations of adjuvants

48Hour Discovery and Merck join hands to accelerate drug development

The role of nanotechnology in the fight against COVID-19

WHA’s president outlines plans to improve treatments for patients with hepatitis

Neutralizing antibodies induced by COVID-19 vaccines less effective against new variants

SARS-CoV-2 did not change much when it jumped from bats to human hosts

Study shows link between financial strain, homelessness and severe mental illness

Scientists increase potency of HIV-1 antibody, identify new ways to develop vaccines

High obesity rates in Southern states magnify Covid threat

Researchers shed light on T-cell receptor activation in response to infection

Neutralizing antibodies may be evolving to keep up with SARS-CoV-2 mutations

Home delivery of HIV medicines could increase ART adherence, viral suppression

Inflammation linked to intensity of tobacco smoking among HIV-positive people

Biden’s criticism of Trump team’s vaccine contracts is a stretch

Novavax COVID-19 vaccine shows efficacy against South African SARS-CoV-2 variant

Innovative cancer treatment effective in combating fungal infection in vitro and in mice

Study demonstrates long-term neuropsychological consequences following SARS-CoV-2 infection

New computer algorithm offers a path toward pan-influenza and coronavirus vaccine

Experimental therapy delays viral rebound in SHIV-infected macaques

Protein kinase inhibitors could help treat immunodeficiency in HIV patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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