Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Gut microbiome plays a role in Alzheimer's

In a recent review published in the journal Pharmacological Research, researchers in Brazil investigated the role of gut microbiota in cognition, brain function, behavior, and neurodegenerative disease pathogenesis.

17 Nov 2022

Research highlights an understudied aspect of Alzheimer’s disease

Memory loss is often the first sign of Alzheimer's disease, followed by confusion and difficulty thinking. These symptoms reflect the typical pattern of worsening damage to brain tissues. Toxic clusters of proteins first concentrate in the temporal lobes of the brain - the memory area - before spreading to parts of the brain important for thinking and planning.

17 Nov 2022

Key Alzheimer’s gene alters the way cholesterol moves around the brain, research finds

A gene recognized as the strongest risk factor for Alzheimer's disease (AD) alters the way cholesterol moves around the brain and as we age, this altered movement likely contributes to loss of learning and memory, a team of researchers from the Icahn School of Medicine at Mount Sinai and the Massachusetts Institute of Technology reports.

16 Nov 2022

Amyloid-PET scanning has misled the FDA into granting approval for Aduhelm

Last year, the FDA gave accelerated approval of the antibody aducanumab (marketed as Aduhelm by Biogen) for the treatment of Alzheimer's disease.

16 Nov 2022

Can a multicultural healthy diet reduce cognitive decline and Alzheimer's disease risk?

Scientists conducted a pilot randomized controlled clinical trial to investigate whether a multicultural healthy diet can reduce cognitive decline and Alzheimer’s disease risk in adults aged 40 – 65.

16 Nov 2022

Utilizing marine sources to extract DHA to treat Alzheimer’s

The anti-neurodegenerative effects of docosahexaenoic acid (DHA) and DHA-rich phospholipids (DH-PL) derived from fisheries and aquaculture byproducts.

15 Nov 2022

The brain's claustrum behaves more like a high-speed internet router, research finds

Tucked underneath the brain's outer, wrinkly cortex is a deeply mysterious area, known as the claustrum. This region has long been known to exchange signals with much of the cortex, which is responsible for higher reasoning and complex thought.

14 Nov 2022

New online tool launched to increase awareness and participation in Alzheimer’s clinical trials

Also at AAIC 2021, the National Institute on Aging (NIA), part of the U.S. National Institutes of Health, launched a new online tool, Outreach Pro, to help researchers and clinicians increase awareness and participation in clinical trials on Alzheimer's disease and other dementias, especially among traditionally underrepresented communities.

14 Nov 2022

Older adults suffer from persistent cognitive impairment after recovery from SARS-CoV-2 infection

In addition to the respiratory and gastrointestinal symptoms that accompany COVID-19, many people with the virus experience short- and/or long-term neuropsychiatric symptoms, including loss of smell and taste, and cognitive and attention deficits, known as "brain fog."

14 Nov 2022

How air pollution affects the central nervous system over time

An article published in the journal Toxics describes how air pollutants adversely impact the human nervous system.

13 Nov 2022

People with Alzheimer's disease can be identified before any symptoms appear

A large study led by Lund University in Sweden has shown that people with Alzheimer's disease can now be identified before they experience any symptoms.

11 Nov 2022

Study shows biological link between muscle weakness and acceleration in biological age

Everyone ages at a different pace. That's why two 50-year-olds, despite living the same number of years, may have different biological ages – meaning that a host of intrinsic and extrinsic factors have caused them to age at varying paces with different levels of risk for disease and early death.

10 Nov 2022

The roles of innate and adaptive immunity in Alzheimer’s disease development and progression

Researchers reviewed research advancements showing the significant role both innate and adaptive immune systems play in the pathological course of Alzheimer’s disease.

10 Nov 2022

Characteristics of patients' drawing process can determine the type of dementia, study finds

The two most common neurodegenerative dementias are Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). There is often an overlap of symptoms across these two diseases, which can make diagnoses difficult.

9 Nov 2022

New biomarker could aid in early diagnosis of Alzheimer’s disease

A definitive diagnosis of Alzheimer's disease (AD) was once only possible after someone had died, but recent biomarker studies have led to the development of imaging and spinal fluid tests for those still living.

9 Nov 2022

Researchers find an innovative approach to improve waste clearance from the brain

Alzheimer's, Parkinson's and many other neurodegenerative diseases are marked by damaging clusters of proteins in the brain. Scientists have expended enormous effort searching for ways to treat such conditions by clearing these toxic clusters but have had limited success.

9 Nov 2022

Researchers use lasso-grafting for designing receptor agonists with enhanced pharmacokinetics

Cell growth and repair are stimulated by biomolecules known as cytokines and growth factors. Unfortunately, delivering adequate concentrations of these molecules to the brain for treating neurological conditions like Alzheimer's disease is challenging as they are either cleared out of the blood very quickly or do not penetrate neural tissue effectively.

8 Nov 2022

Alzheimer's Disease News and Research

Further Reading

Gut microbiome plays a role in Alzheimer's

Research highlights an understudied aspect of Alzheimer’s disease

Key Alzheimer’s gene alters the way cholesterol moves around the brain, research finds

Amyloid-PET scanning has misled the FDA into granting approval for Aduhelm

Can a multicultural healthy diet reduce cognitive decline and Alzheimer's disease risk?

Utilizing marine sources to extract DHA to treat Alzheimer’s

The brain's claustrum behaves more like a high-speed internet router, research finds

New online tool launched to increase awareness and participation in Alzheimer’s clinical trials

Older adults suffer from persistent cognitive impairment after recovery from SARS-CoV-2 infection

How air pollution affects the central nervous system over time

People with Alzheimer's disease can be identified before any symptoms appear

Study shows biological link between muscle weakness and acceleration in biological age

The roles of innate and adaptive immunity in Alzheimer’s disease development and progression

Characteristics of patients' drawing process can determine the type of dementia, study finds

New biomarker could aid in early diagnosis of Alzheimer’s disease

Researchers find an innovative approach to improve waste clearance from the brain

Researchers use lasso-grafting for designing receptor agonists with enhanced pharmacokinetics

UQ researchers discover a link between obstructive sleep apnea and dementia

COVID-19 amplifies damage to the central nervous system in Alzheimer's disease

Beer hop compounds could serve as the basis for nutraceuticals to combat Alzheimer’s disease

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