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COVID-19 vaccination increases saliva antibody levels after asymptomatic infection

Researchers correlate SARS-CoV-2 load and neutralizing capacity of all saliva immunoglobulins isotypes in asymptomatic individuals.

8 Feb 2023

Expert work group examines and redefines “clinical meaningfulness” in Alzheimer’s

As the Alzheimer's disease scientific community, patients, and families seek to understand the results of clinical trials of new Alzheimer's treatments, the Alzheimer's Association convened an expert work group to discuss an important and timely issue: the "clinical meaningfulness" of results from these studies.

7 Feb 2023

Study shows activation of pulmonary macrophages by SARS-CoV-2 spike glycoprotein

In a recent study published in the International Journal of Molecular Sciences, researchers investigated the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein on human lung macrophage (HLM) activation and angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) expression in human lung macrophages.

7 Feb 2023

Understanding the relationship between SARS-CoV-2 infection and periodontitis

In a recent review published in the journal International Journal of Molecular Sciences, researchers reviewed existing data on the association between periodontitis and coronavirus disease 2019 (COVID-19).

7 Feb 2023

Symptomatic SARS-CoV-2 infection during pregnancy increases risk of complications for mother and infant

Researchers investigate the obstetric and neonatal outcomes in unvaccinated pregnant females infected with the SARS-CoV-2.

7 Feb 2023

Study finds high levels of hydrogen peroxide in pancreatic cancer cells

Reactive oxygen species (ROS) are reputed for their involvement in carcinogenesis. Results from a study published in the journal Angewandte Chemie have now shown that the level of one such ROS,

7 Feb 2023

Study characterizes mutations in neuraminidase of human-like H5N1 influenza viruses

A study published in PLOS PATHOGENS describes the prevalence and functions of mutations in neuraminidase enzyme of avian H5N1 influenza viruses that are preferentially selected in human H5N1 influenza viruses.

7 Feb 2023

The safety profile and the actual known adverse effects of COVID-19 vaccines in at-risk and healthy individuals

Researchers discussed the safety of COVID-19 vaccines in healthy people and patients with autoimmunity or cardiac issues.

7 Feb 2023

Owlstone Medical Publishes Data on the Use of Exhaled Volatile Organic Compounds as Biomarkers for Liver Disease Detection

Owlstone Medical (“Owlstone”), the global leader in Breath Biopsy® for applications in early disease detection and precision medicine, today announced the publication of a peer-reviewed study in the Journal of Clinical and Translational Hepatology, “Breath Biopsy to identify exhaled volatile organic compounds as biomarkers for liver cirrhosis detection”.

From Owlstone Medical Ltd 7 Feb 2023

Gut hormone receptor polyagonists show promise for obesity and diabetes

A new paper in the Journal of Clinical Investigation describes drugs that could help lose weight and manage type 2 diabetes mellitus (T2DM).

6 Feb 2023

Diet, microbial metabolites, and cytokine levels correlate with depression and anxiety symptoms in obese individuals

Researchers determine the association between diet, microbe-derived metabolites, and cytokine levels with anxiety and depression among obese adults.

6 Feb 2023

Targeting a single enzyme can kill prostate cancer cells

For the first time, researchers have discovered that prostate cancer can be killed by targeting a single enzyme, called PI5P4Kα.

3 Feb 2023

The impact of viral infections on the human endocrine system

Researchers briefly outlined how viral infections trigger endocrinopathies in humans.

3 Feb 2023

The relationship between natural plant extracts and SARS-CoV-2

Researchers explored plants as an extensive resource of molecules with potential therapeutic action against SARS-CoV-2 and debunked misconceptions.

3 Feb 2023

What is the effect of sex on the clinical characteristics and prognosis of COVID-19 patients?

Researchers evaluated COVID-19 management based on sex differences.

3 Feb 2023

Novel tool uses AI to predict the efficacy of genome-editing repair options

Researchers at the University of Zurich have developed a new tool that uses artificial intelligence to predict the efficacy of various genome-editing repair options.

2 Feb 2023

Establishment of a rapid and accurate SARS-CoV-2 antigen detection kit able to identify Omicron mutants

Researchers developed an antigen detection kit to identify the SARS-CoV-2 Omicron variant of concern.

2 Feb 2023

Researchers report a heterologous vaccination strategy against IBV in Chickens

Researchers reported on the immunogenicity of a heterologous vaccine regimen against IBV, comprising prime doses of QAC-encapsulated plasmid and a booster dose of MVA.

2 Feb 2023

The trajectory of long-COVID in the general population of Scotland

Researchers presented the findings of the Long-COVID in Scotland Study (Long-CISS) conducted nationwide among the general population of Scotland.

2 Feb 2023

Breakthrough Omicron BA.1/BA.2 infections in the triple-vaccinated linked to broad-based immunity

A new study looked at the whole spectrum of immunological reactions raised by spike and non-spike antigens following Omicron BA.1/BA.2 infections in such individuals, both with and without prior SARS-CoV-2 infection.

1 Feb 2023

Enzyme News and Research

COVID-19 vaccination increases saliva antibody levels after asymptomatic infection

Expert work group examines and redefines “clinical meaningfulness” in Alzheimer’s

Study shows activation of pulmonary macrophages by SARS-CoV-2 spike glycoprotein

Understanding the relationship between SARS-CoV-2 infection and periodontitis

Symptomatic SARS-CoV-2 infection during pregnancy increases risk of complications for mother and infant

Study finds high levels of hydrogen peroxide in pancreatic cancer cells

Study characterizes mutations in neuraminidase of human-like H5N1 influenza viruses

The safety profile and the actual known adverse effects of COVID-19 vaccines in at-risk and healthy individuals

Owlstone Medical Publishes Data on the Use of Exhaled Volatile Organic Compounds as Biomarkers for Liver Disease Detection

Gut hormone receptor polyagonists show promise for obesity and diabetes

Diet, microbial metabolites, and cytokine levels correlate with depression and anxiety symptoms in obese individuals

Targeting a single enzyme can kill prostate cancer cells

The impact of viral infections on the human endocrine system

The relationship between natural plant extracts and SARS-CoV-2

What is the effect of sex on the clinical characteristics and prognosis of COVID-19 patients?

Novel tool uses AI to predict the efficacy of genome-editing repair options

Establishment of a rapid and accurate SARS-CoV-2 antigen detection kit able to identify Omicron mutants

Researchers report a heterologous vaccination strategy against IBV in Chickens

The trajectory of long-COVID in the general population of Scotland

Breakthrough Omicron BA.1/BA.2 infections in the triple-vaccinated linked to broad-based immunity

Understanding the DNA Damage Response in Innate Immunity eBook

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