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Medicare seeks comment on ways to cut costs of Part D drugs

Noting that the true price of a drug is often hidden from consumers, Medicare officials requested comments late Thursday on how to use discounts and rebates to help decrease what enrollees pay for prescriptions.

16 Nov 2017

Separating side effects could pave way for safe, effective pain medications

Opioid pain relievers can be extremely effective in relieving pain, but can carry a high risk of addiction and ultimately overdose when breathing is suppressed and stops.

16 Nov 2017

Researchers develop computer program to find new indications for old drugs

Researchers at the Case Comprehensive Cancer Center at Case Western Reserve University School of Medicine have developed a computer program to find new indications for old drugs.

16 Nov 2017

Brazilian Zika epidemic could soon be over, say scientists

In 2016, news about the Zika virus in Brazil made the headlines in Europe for the first time. With approximately 65 million people affected, it is one of the largest epidemics in the last few years.

16 Nov 2017

One in 20 children still receiving codeine to treat pain despite warning from federal regulators

A new study shows as many as one in 20 children were still receiving codeine to treat pain after tonsil and adenoid surgery, two years after federal regulators warned doctors that prescribing the opioid to kids after the routine surgeries could be fatal.

16 Nov 2017

Common ingredient in laundry detergents may help build bioartificial pancreas to cure type 1 diabetes

Two oxygen-producing compounds – including one that boosts performance in some laundry detergents – might one day play a key role in helping scientists successfully build a bioartificial pancreas in the lab to cure type 1 diabetes.

16 Nov 2017

Vaping liquid may increase risk for complications during and after surgery

Despite being perceived as a 'healthier' alternative to tobacco cigarettes, vaping liquid contains nicotine, which may significantly increase the risk for complications related to surgery and anesthesia, according to the American Association of Nurse Anesthetists.

16 Nov 2017

FDA permits marketing of first electric stimulation device to reduce opioid withdrawal symptoms

Today, the U.S. Food and Drug Administration granted a new indication to an electric stimulation device for use in helping to reduce the symptoms of opioid withdrawal.

16 Nov 2017

New study identifies chemical receptors in cells to reduce drug resistance

The bacterium Pseudomonas aeruginosa is the leading cause of hospital-acquired infections. The pathogen is resistant to many antibiotics so treating those infections, particularly in patients with compromised immune systems, is difficult.

15 Nov 2017

Genetic diversity of tumor tissues can be barrier to precision medicine in gastric and esophageal cancers

A new study focused on describing genetic variations within a primary tumor, differences between the primary and a metastatic branch of that tumor, and additional diversity found in tumor DNA in the blood stream could help physicians make better treatment choices for patients with gastric and esophageal adenocarcinoma.

15 Nov 2017

FDA approves drug to treat pediatric, adult patients with rare Sly syndrome

The U.S. Food and Drug Administration today approved Mepsevii (vestronidase alfa-vjbk) to treat pediatric and adult patients with an inherited metabolic condition called mucopolysaccharidosis type VII (MPS VII), also known as Sly syndrome. MPS VII is an extremely rare, progressive condition that affects most tissues and organs.

15 Nov 2017

Intensive glucose control in type 2 diabetes patients can increase mortality risk, study finds

The common approach of intensive glucose control to achieve low blood sugar targets in type 2 diabetes can increase the risk of mortality, finds a study by Cardiff University.

15 Nov 2017

Nanowires could be potential drug delivery tools for neurodegenerative diseases

Millions of Americans suffer from neurodegenerative diseases such as Alzheimer's and Parkinson's. Researchers have identified promising new treatments, such as cerebrolysin, but current clinical approaches are ineffective because critical concentrations of the drug dissipate within the body before reaching the blood-brain barrier and central nervous system.

15 Nov 2017

Machine learning could detect therapeutic effects with greater sensitivity than conventional tests

Machine learning could improve our ability to determine whether a new drug works in the brain, potentially enabling researchers to detect drug effects that would be missed entirely by conventional statistical tests, finds a new UCL study published in Brain.

15 Nov 2017

Changes in multiple different genes drive world's most deadly forms of lung cancer

A new UC San Francisco–led study challenges the dogma in oncology that most cancers are caused by one dominant "driver" mutation that can be treated in isolation with a single targeted drug. Instead, the new research finds one of the world's most deadly forms of lung cancer is driven by changes in multiple different genes, which appear to work together to drive cancer progression and to allow tumors to evade targeted therapy.

15 Nov 2017

FDA warns consumers about injuries, disfigurement from using illegal injectable silicone

The U.S. Food and Drug Administration today issued a safety communication to warn consumers and health care practitioners about the serious injuries and disfigurement that can result from using injectable silicone or products being falsely marketed as FDA-approved dermal fillers for the purpose of enhancing the size of their buttocks, breasts and other body parts.

14 Nov 2017

AstraZeneca’s new precision biologic gets FDA approval to treat severe eosinophilic asthma

AstraZeneca and its global biologics research and development arm, MedImmune, today announced that the US Food and Drug Administration has approved FASENRA (benralizumab) for the add-on maintenance treatment of patients with severe asthma aged 12 years and older, and with an eosinophilic phenotype.

14 Nov 2017

MDA announces 13 new research grants to advance treatment for neuromuscular diseases

The Muscular Dystrophy Association today announced 13 new research and development grants totaling $3.5 million to accelerate the development of treatments for muscular dystrophy, ALS and related life-threatening diseases.

14 Nov 2017

Tulane professor wins Department of Defense grant for research into arteriovenous malformations

Tulane University's Stryder Meadows, a cell and molecular biology professor, received a $1.7 million grant from the Department of Defense to study how arteriovenous malformations (AVM), which are defects in arteries, veins and capillaries, form Hereditary Hemorrhagic Telangiectasia (HHT), a genetic disorder that affects about 1 in 5,000 people.

14 Nov 2017

Nanoparticles carrying CRISPR gene editing tools for genetic modifications

Researchers from MIT have now developed nanoparticles that could carry CRISPR genetic editing systems deep within the cells and perform their functions on the DNA. The paper was published in the November issue of Nature Biotechnology.

14 Nov 2017

Drugs News and Research

Medicare seeks comment on ways to cut costs of Part D drugs

Separating side effects could pave way for safe, effective pain medications

Researchers develop computer program to find new indications for old drugs

Brazilian Zika epidemic could soon be over, say scientists

One in 20 children still receiving codeine to treat pain despite warning from federal regulators

Common ingredient in laundry detergents may help build bioartificial pancreas to cure type 1 diabetes

Vaping liquid may increase risk for complications during and after surgery

FDA permits marketing of first electric stimulation device to reduce opioid withdrawal symptoms

New study identifies chemical receptors in cells to reduce drug resistance

Genetic diversity of tumor tissues can be barrier to precision medicine in gastric and esophageal cancers

FDA approves drug to treat pediatric, adult patients with rare Sly syndrome

Intensive glucose control in type 2 diabetes patients can increase mortality risk, study finds

Nanowires could be potential drug delivery tools for neurodegenerative diseases

Machine learning could detect therapeutic effects with greater sensitivity than conventional tests

Changes in multiple different genes drive world's most deadly forms of lung cancer

FDA warns consumers about injuries, disfigurement from using illegal injectable silicone

AstraZeneca’s new precision biologic gets FDA approval to treat severe eosinophilic asthma

MDA announces 13 new research grants to advance treatment for neuromuscular diseases

Tulane professor wins Department of Defense grant for research into arteriovenous malformations

Nanoparticles carrying CRISPR gene editing tools for genetic modifications

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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