Cell Proliferation News and Research

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New monoclonal antibody enhances immune response by selectively targeting Tregs

A new research paper was published in Volume 16 of Oncotarget on July 9, 2025, titled "A novel anti-human CD25 mAb with preferential reactivity to activated T regulatory cells depletes them from the tumor microenvironment."

17 Jul 2025

WEE1 identified as a key driver of immune resistance in cancer

Immune checkpoints are regulatory proteins that prevent the immune system from attacking healthy tissues.

15 Jul 2025

Scientists discover how two distinct genes guide regeneration of sensory cells in zebrafish

While humans can regularly replace certain cells, like those in our blood and gut, we cannot naturally regrow most other parts of the body. For example, when the tiny sensory hair cells in our inner ears are damaged, the result is often permanent hearing loss, deafness, or balance problems.

14 Jul 2025

Single-cell sequencing maps immune changes in chronic myeloid leukemia

Chronic myeloid leukemia (CML) is a hematopoietic malignancy characterized by BCR-ABL1 gene fusion.

9 Jul 2025

Retinal organoid model advances understanding of dry age-related macular degeneration

Age-related macular degeneration (AMD), classified into dry and wet types, poses a significant threat to the vision of the elderly population globally.

9 Jul 2025

Metabolic enzyme PHGDH found to play a surprising role in breast cancer immunity

Macrophages are immune cells with a split personality: some fight tumors, while others help them grow. In breast cancer, most macrophages fall into the latter camp—dubbed M2-like—fueling tumor progression and dampening immune responses.

7 Jul 2025

Flavonoid diversity, not just quantity, drives better health outcomes

This study reveals that diverse flavonoid intake is crucial for lowering chronic disease risk and mortality, advocating for a varied diet rich in flavonoids.

7 Jul 2025

Amino acid metabolism in breast cancer as a driver of disease and therapeutic target

The review introduces the molecular subtypes of breast cancer and outlines how altered amino acid metabolism supports tumor growth.

7 Jul 2025

XPR1 silencing enhances immune response and reduces ovarian tumor growth

A recent study published in Genes & Diseases reveals a novel role of XPR1 in promoting ovarian cancer growth by regulating autophagy and MHC-I expression.

4 Jul 2025

EMP1 identified as key driver of tumor progression in resectable pancreatic cancer

The latest research published in Genes & Diseases unveils groundbreaking insights into the role of the aging process and the associated factor EMP1 in the progression of resectable pancreatic cancer (PC).

4 Jul 2025

NAD+ supplementation could be a potential treatment for accelerated aging diseases

Can research into a rare, accelerated aging disease and "zombie cells" teach us something about the normal aging process?

4 Jul 2025

Aromatic benzaldehyde inhibits growth of therapy-resistant pancreatic cancer

During therapy, some cancer cells evolve to escape elimination. Newer anticancer drugs that can overcome this resistance are necessary.

2 Jul 2025

Study enhances the understanding of urolithiasis pathogenesis

A recent study published in Genes & Diseases reveals new insights into the relationship between immune cell characteristics, blood metabolites, and the risk of urolithiasis.

2 Jul 2025

Single-cell transcriptomes of immune cells offer insight into juvenile idiopathic arthritis

Juvenile idiopathic arthritis (JIA), a type of arthritis commonly occurring in children, is a chronic, inflammatory condition that affects the joints, causing pain, swelling, stiffness, and limiting the range of motion.

2 Jul 2025

Rarely studied RNA linked to triple-negative breast cancer

Breast cancer is one of the most common cancers among women in the United States. Thanks to decades of fundamental research, it's also one of the most curable.

1 Jul 2025

VIRMA protein regulates brain development by controlling ribosome biogenesis

Ribosomes are tiny molecular machines inside all living cells that build proteins, and ribosome biogenesis is the complex, multi-step process by which they are made.

30 Jun 2025

Epigenetic enzyme SETD1B drives aggressive growth in acute myeloid leukemia

Acute myeloid leukemia (AML) is an aggressive cancer affecting the blood and bone marrow that progresses rapidly, making immediate treatment essential.

26 Jun 2025

Ribonucleases revealed as key players in Mendelian disorders

A new review brings to light the pivotal role of ribonucleases (RNases) in shaping the molecular foundation of Mendelian disorders.

26 Jun 2025

Targeting the tumor microenvironment to improve osteosarcoma outcomes

The complex tumor microenvironment (TME) in osteosarcoma is emerging as a critical factor in disease progression and treatment resistance.

26 Jun 2025

Study reveals vitamin C’s role in strengthening aging skin

The skin acts as the body's first line of defense against external threats. However, as we age, the epidermis-the outermost layer of skin-gradually becomes thinner and loses its protective strength.

25 Jun 2025

Cell Proliferation News and Research

New monoclonal antibody enhances immune response by selectively targeting Tregs

WEE1 identified as a key driver of immune resistance in cancer

Scientists discover how two distinct genes guide regeneration of sensory cells in zebrafish

Single-cell sequencing maps immune changes in chronic myeloid leukemia

Retinal organoid model advances understanding of dry age-related macular degeneration

Metabolic enzyme PHGDH found to play a surprising role in breast cancer immunity

Flavonoid diversity, not just quantity, drives better health outcomes

Amino acid metabolism in breast cancer as a driver of disease and therapeutic target

XPR1 silencing enhances immune response and reduces ovarian tumor growth

EMP1 identified as key driver of tumor progression in resectable pancreatic cancer

NAD+ supplementation could be a potential treatment for accelerated aging diseases

Aromatic benzaldehyde inhibits growth of therapy-resistant pancreatic cancer

Study enhances the understanding of urolithiasis pathogenesis

Single-cell transcriptomes of immune cells offer insight into juvenile idiopathic arthritis

Rarely studied RNA linked to triple-negative breast cancer

VIRMA protein regulates brain development by controlling ribosome biogenesis

Epigenetic enzyme SETD1B drives aggressive growth in acute myeloid leukemia

Ribonucleases revealed as key players in Mendelian disorders

Targeting the tumor microenvironment to improve osteosarcoma outcomes

Study reveals vitamin C’s role in strengthening aging skin

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