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Disorientating the malaria parasite to prevent its replication and transmission

With almost 250 million cases a year, 621,000 of them fatal, malaria remains a major public health problem, particularly in sub-Saharan Africa.

16 Jun 2023

Experts identify a novel fucosylated heparan sulfate from the midgut gland of the Japanese scallop

Glycosaminoglycans (GAGs), including chondroitin sulfate (CS), heparan sulfate (HS), heparin, and hyaluronan are linear and acidic polysaccharides found in the extracellular matrix of all animal tissues. GAGs are widely used as functional ingredients in health products, pharmaceuticals, and cosmetics, and are prepared from biological samples such as shark cartilage and porcine intestinal mucosa. Consequently, the demand for new sources of GAGs is ever-present. For example, the supply source of the anticoagulant heparin-;generally prepared from porcine intestinal mucosa in China-;was threatened by African swine fever in 2018.

15 Jun 2023

Study reveals potential bioterrorism agents and urges enhanced biosecurity measures

Research paper provides pathogen incidences for potential bioterrorism agents in the Netherlands from 2009 to 2019. The study highlights the need for biosecurity measures based on the observed incidences.

15 Jun 2023

Molecular insights into long COVID: serum proteome reveals dominant signaling pathways

Researchers examined the serum proteome of unvaccinated adults who had PASC.

15 Jun 2023

Exploring how Bourbon virus-carrying ticks travel through wildlife and to people

On a cold spring morning, Washington University in St. Louis virologist Jacco Boon, PhD, and wildlife ecologist Solny Adalsteinsson, PhD, flap and drag a large white flag through a woodsy area on the western edge of St. Louis County. Boon, an associate professor of medicine in infectious diseases at Washington University School of Medicine in St. Louis, and Adalsteinsson, a senior scientist at the university's Tyson Research Center, are looking for lone star ticks that carry the potentially deadly Bourbon virus.

14 Jun 2023

An analysis of the differential effect and the impact of SARS-CoV-2 infection on semen quality

Study analyzed the impact of SARS-CoV-2 infection on semen quality.

14 Jun 2023

Deep learning models could be crucial in battling the monkeypox virus

Researchers developed a machine-learning-based detection tool to detect mpox.

14 Jun 2023

Researchers explore viral emissions in a phase 1, open label, first-in-human SARS-CoV-2 experimental infection study

Researchers explored the release of viral particles into the environment and air after SARS-CoV-2 human challenge.

13 Jun 2023

VLA1553 vaccine candidate for chikungunya disease produces an immune response in a phase 3 trial

The VLA1553 vaccine candidate for chikungunya disease was generally well tolerated and produced an immune response in 99% (263/266) of participants, according to a phase 3 randomized controlled trial published in The Lancet.

12 Jun 2023

Vaccine against deadly chytrid fungus shifts microbiome to make frogs more resilient to future exposure

A human or animal's microbiome -; the collection of often beneficial microorganisms, including as bacteria and fungi, that live on or within a host organism -; can play an important role in the host's overall immune response, but it is unclear how vaccines against harmful pathogens impact the microbiome.

11 Jun 2023

Mechanistic insights into how the SARS-CoV-2 virus affects the nervous system, alters its function, and causes neuropathology

Study demonstrates that SARS-CoV-2 infection and viral fusogens cause glial and neuronal fusion.

9 Jun 2023

MIS-C in children: A distinct autoimmune response to COVID-19 unveiled

The study reveals that MIS-C patients, post SARS-CoV-2 infection, develop a unique immune response against the virus' N protein, indicating a cross-reactivity with the self-protein SNX8, which might link the infection to the ensuing inflammatory syndrome.

8 Jun 2023

Gut health boost: Functional foods and herbs show promise in tackling SARS-CoV-2 variants

Functional foods and natural herbs have the potential to enhance immune function and maintain gut microbiota diversity. This review explores their role in mitigating the impact of SARS-CoV-2 variants on gut health and overall well-being.

8 Jun 2023

Yellow fever: examining potential burden on vaccine strategy

Researchers presented a stochastic model of yellow fever transmission.

8 Jun 2023

Study identifies a promising target for development of vaccine against spotted fever

A protein found in cells of the hard tick Amblyomma sculptum, the main vector of the bacterium that causes Brazilian spotted fever (also known as Rocky Mountain spotted fever), is essential to the tick's survival while feeding, making it a promising target for development of a vaccine, according to an article published in the journal Parasites & Vectors.

7 Jun 2023

Researchers zero in on a potential new target for malaria: Biological clocks

Health officials warn that drug resistance could wipe out recent progress against malaria, particularly in Africa and southeast Asia.

6 Jun 2023

What role did children play in household viral transmission during the COVID-19 pandemic, when enveloped virus rates were low, and relative proportions of COVID-19 were high?

Researchers performed a cohort study on a voluntary group in the United States.

6 Jun 2023

Study analyzes chatbots through a health equity lens

Chatbots are increasingly becoming a part of health care around the world, but do they encourage bias? That's what University of Colorado School of Medicine researchers are asking as they dig into patients' experiences with the artificial intelligence (AI) programs that simulate conversation.

6 Jun 2023

CDC reports an alarming rise in pediatric intracranial infections in the U.S.

Researchers confirm the occurrence of a cluster of intracranial infections and identify the risk factors responsible for this increase.

5 Jun 2023

The clinical and virological characteristics of severe neonatal echovirus 11 infections

Researchers described severe and fatal infections in neonates caused by a new echovirus 11 (E-11) variant in France.

5 Jun 2023

Fever News and Research

Disorientating the malaria parasite to prevent its replication and transmission

Experts identify a novel fucosylated heparan sulfate from the midgut gland of the Japanese scallop

Study reveals potential bioterrorism agents and urges enhanced biosecurity measures

Molecular insights into long COVID: serum proteome reveals dominant signaling pathways

Exploring how Bourbon virus-carrying ticks travel through wildlife and to people

An analysis of the differential effect and the impact of SARS-CoV-2 infection on semen quality

Deep learning models could be crucial in battling the monkeypox virus

Researchers explore viral emissions in a phase 1, open label, first-in-human SARS-CoV-2 experimental infection study

VLA1553 vaccine candidate for chikungunya disease produces an immune response in a phase 3 trial

Vaccine against deadly chytrid fungus shifts microbiome to make frogs more resilient to future exposure

Mechanistic insights into how the SARS-CoV-2 virus affects the nervous system, alters its function, and causes neuropathology

MIS-C in children: A distinct autoimmune response to COVID-19 unveiled

Gut health boost: Functional foods and herbs show promise in tackling SARS-CoV-2 variants

Yellow fever: examining potential burden on vaccine strategy

Study identifies a promising target for development of vaccine against spotted fever

Researchers zero in on a potential new target for malaria: Biological clocks

What role did children play in household viral transmission during the COVID-19 pandemic, when enveloped virus rates were low, and relative proportions of COVID-19 were high?

Study analyzes chatbots through a health equity lens

CDC reports an alarming rise in pediatric intracranial infections in the U.S.

The clinical and virological characteristics of severe neonatal echovirus 11 infections

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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