Glucocorticoid News and Research

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Glucocorticoid is a compound that belongs to the family of compounds called corticosteroids (steroids). Glucocorticoids affect metabolism and have anti-inflammatory and immunosuppressive effects. They may be naturally produced (hormones) or synthetic (drugs).

Cumulative doses of oral steroids associated with increased hypertension

Cumulative doses of oral steroids in patients with chronic inflammatory diseases are associated with increased hypertension (blood pressure) for those who take them regularly, found new research in CMAJ.

23 Mar 2020

Stress during pregnancy can cause lifetime of immune system deficiencies

Mice exposed to stress in the womb and soon after birth can expect a lifetime of immune system deficiencies that hinder the ability to ward off infections and cancer, Yale University researchers report March 5 in the journal Cell.

5 Mar 2020

Stress in kids could have long term genetic consequences finds study

Researchers have found that being separated from parents at a young age could lead to a rise in stress hormones, which could have direct consequences on altering the genetic makeup of the child, which can then be passed on to the future generations. The study titled, "Childcare outside the family for the under-threes: cause for concern?" was published in the latest issue of the Journal of the Royal Society of Medicine.

16 Feb 2020

Research paves the way to improved treatment for complex blood disorders

Nearly 1.6 billion people worldwide suffer from anemia, and for the first time new research points to how resistance emerges to the drug dexamethasone used to treat the devastating inherited form of anemia known as Diamond Blackfan anemia.

22 Jan 2020

Study sets the record straight on unproven therapy to treat sepsis

The Jan. 17 issue of the Journal of the American Medical Association features an important study about sepsis with an accompanying editorial by a University of Nebraska Medical Center expert.

17 Jan 2020

Researchers uncover genetic anomaly linked with poor response to common asthma treatment

A new Cleveland Clinic study has uncovered a genetic anomaly associated with poor response to a common asthma treatment.

13 Jan 2020

Gadolinium-enhanced MRI of shoulders helps predict recurrence of polymyalgia rheumatica

According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, use of gadolinium-enhanced magnetic resonance imaging (MRI) in shoulders of patients with polymyalgia rheumatica may contribute to more accurate diagnosis and prediction of recurrence.

11 Nov 2019

Study shows how glucocorticoid hormones control sugar and fat levels over the course of 24 hours

For the first time, a study led by researchers at Helmholtz Zentrum München and the German Center for Diabetes Research shows how glucocorticoid hormones, such as cortisol, control sugar and fat levels differently during day and night, feeding and fasting, rest and activity, over the course of 24 hours.

10 Nov 2019

Northwestern Medicine launches program to help women understand risk factors for osteoporosis

Loss of bone density is common as women age, particularly around menopause when women lose more bone than they make. When bone density becomes so low that fracture is likely, the condition is called osteoporosis.

23 Oct 2019

Researchers propose potential treatment for Ewing sarcomas

Ewing sarcoma is a bone cancer that appears mainly in teenagers. Due to a single defective gene, once it spreads to distant organs it is hard to treat. Researchers at the Weizmann Institute of Science have discovered molecular interactions underlying Ewing sarcomas and proposed a potential treatment, which has shown promise in a study in mice.

2 Oct 2019

Clinical trial to evaluate efficacy and safety of new treatment for giant cell arteritis

An international, multicenter phase II clinical trial is evaluating the efficacy and safety of mavrilimumab co-administered with a 26-week corticosteroid taper in patients with giant cell arteritis.

26 Sep 2019

Study finds nearly one in three patients with lupus uses prescription opioids for pain

Although there is little evidence that opioids effectively reduce pain from rheumatic diseases, a new study finds nearly one in three patients with lupus uses prescription opioids, often lasting longer than a year.

26 Sep 2019

Strong family bonding improves helps child's asthma

Want to help your child deal with asthma better? A new Northwestern University study says one way is to build a sturdy sense of family bonding, especially in dangerous neighborhoods.

18 Jul 2019

New drug provides hope for patients with Duchenne muscular dystrophy

The results from three clinical trials have shown that a new drug can successfully delay the progression of Duchenne muscular dystrophy.

10 Jul 2019

Oral steroid use in patients with inflammatory diseases increases risk of infection

Oral steroid use in patients with the inflammatory diseases polymyalgia rheumatica and/or giant cell arteritis significantly increased the risk of infection, and the risk increased with higher doses, found a study in CMAJ.

24 Jun 2019

Study shows high levels of success in most patients despite tapered glucocorticoid discontinuation

The results of a randomized controlled trial presented today at the Annual European Congress of Rheumatology demonstrate high levels of treatment success in approximately two thirds of patients despite tapered glucocorticoid discontinuation, while a small loss of disease control was observed at the total study population level.

13 Jun 2019

Glucocorticoid News and Research

Cumulative doses of oral steroids associated with increased hypertension

Stress during pregnancy can cause lifetime of immune system deficiencies

Stress in kids could have long term genetic consequences finds study

Research paves the way to improved treatment for complex blood disorders

Study sets the record straight on unproven therapy to treat sepsis

Researchers uncover genetic anomaly linked with poor response to common asthma treatment

Gadolinium-enhanced MRI of shoulders helps predict recurrence of polymyalgia rheumatica

Study shows how glucocorticoid hormones control sugar and fat levels over the course of 24 hours

Northwestern Medicine launches program to help women understand risk factors for osteoporosis

Researchers propose potential treatment for Ewing sarcomas

Clinical trial to evaluate efficacy and safety of new treatment for giant cell arteritis

Study finds nearly one in three patients with lupus uses prescription opioids for pain

Strong family bonding improves helps child's asthma

New drug provides hope for patients with Duchenne muscular dystrophy

Oral steroid use in patients with inflammatory diseases increases risk of infection

Study shows high levels of success in most patients despite tapered glucocorticoid discontinuation

Prenatal stress may be involved in shaping psychiatric resilience later in life

ACR and Arthritis Foundation release two guidelines on juvenile idiopathic arthritis

Molecular target UNC45A is essential for cancer cell proliferation and tumor growth

Two proteins act in concert to maintain a healthy heart in mice, shows study

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