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Research provides insight into genetic mechanisms of Wilms tumor

New research from Ann & Robert H. Lurie Children's Hospital of Chicago and collaborators from other institutions provides insights into some of the genetic characteristics resulting in the development of relapse in patients with Wilms tumor (nephroblastoma), the most common type of pediatric cancer of the kidney.

24 May 2022

Scientists explore triggers associated with transplacental transmission of SARS-CoV-2

A new study examines the risk of fetal SARS-CoV-2 infection following infection of a pregnant mother with the virus.

17 May 2022

Researchers Identify Potential Target for Rhabdomyosarcoma Recurrence Prevention

In this interview, News-Medical speaks to Anand Patel and Michael Dyer from St. Jude's Children's Research Hospital about their recent research suggesting EGFR inhibitors may prevent rhabdomyosarcoma recurrence.

12 May 2022

AI model predicts postoperative recurrence of Crohn disease with high accuracy

Using an artificial intelligence (AI) tool that emulates how humans visualize and is trained to recognize and classify images, investigators constructed a model that predicts the postoperative recurrence of Crohn disease with high accuracy by evaluating histological images.

10 May 2022

Identification of a SARS-CoV-2 neutralizing human monoclonal antibody with a remarkable broad-spectrum neutralization and protection efficacy

Researchers identified a human monoclonal antibody (mAb), 87G7, with in vitro neutralizing activity against several SARS-CoV-2 VOCs, including Alpha, Beta, Gamma, Delta, and Omicron.

28 Apr 2022

Non-invasive CGC examination for precision diagnosis of ocular surface diseases in live rabbit eyes

A Korean research team led by Professor Ki Hean Kim, Ph.D. candidates Seonghan Kim and Jungbin Lee (Department of Mechanical Engineering) at POSTECH, in collaboration with Professor Chang Ho Yoon (Department of Ophthalmology) of Seoul National University Hospital and Professor Young-Ho Jung (Department of Ophthalmology) of Eulji Hospital, has successfully demonstrated the non-invasive CGC examination in live rabbit eyes.

28 Apr 2022

Persistent loss of smell after COVID-19 associated with altered olfactory epithelial gene expression

Researchers performed histology of the olfactory epithelium for smell loss measurements in patients with post-acute sequelae of SARS-CoV-2 infection.

20 Apr 2022

New technology could replace conventional biopsies and histology with real-time imaging

MediSCAPE, a high-speed 3D microscope designed by Columbia Engineers, can see real-time cellular detail in living tissues to guide surgery, speed up tissue analyses, and improve treatments.

28 Mar 2022

Biomarker testing in lung cancer patients has increased in real-world clinical practice, study reveals

More than half of patients diagnosed with advanced non-small cell lung cancer (NSCLC) undergo biomarker testing, and this figure has increased over the last five years, reveal real-world data from a Spanish national registry study reported at the European Lung Cancer Congress, 30 March-2 April 2022.

23 Mar 2022

TTUHSC researcher secures $1.9 million grant to investigate vulnerabilities in ALT cancers

The National Cancer Institute, part of the National Institutes of Health, recently awarded a five-year, $ $1.9 million grant to C. Patrick Reynolds, M.D., Ph.D., director for the School of Medicine Cancer Center at the Texas Tech University Health Sciences Center.

23 Mar 2022

Olympus Discovery Center inaugurated at the University of Maryland

Last week, Olympus joined the University of Maryland in celebrating the grand opening of its new Olympus Discovery Center.

From Evident Corporation - Life Sciences 3 Mar 2022

Angiotensin-converting enzyme 2-based mutant decoy effectively reduces COVID-19 in mice

Researchers engineered a mutant ACE2 decoy that effectively protected human lung epithelia from SARS-CoV-2 infection by competitively binding to its spike protein.

3 Mar 2022

Olympus Discovery Center brings advanced microscopy to brain research

Olympus continues to demonstrate its commitment to advancing bioscience research with the opening of the new Olympus Discovery Center at the University of Montreal’s Centre interdisciplinaire de recherche sur le cerveau et l'apprentissage (Center for Interdisciplinary Research on Brain and Learning, or CIRCA).

From Evident Corporation - Life Sciences 25 Feb 2022

Broad-spectrum antiviral activity of picolinic acid against SARS-CoV-2 and Influenza A virus

Researchers investigate the potential of picolinic acid (PA) as an anti-SARS-CoV-2 treatment option.

21 Feb 2022

New set of clinical guidelines published to aid better diagnosis and management of endometriosis

Scientists from UCL and UCLH have informed a new set of clinical guidelines to aid better diagnosis and management of endometriosis - a chronic condition that causes severe pelvic pain and reduced fertility for millions of women worldwide.

18 Feb 2022

ChAdOx1 vaccine found to protect Syrian hamsters against SARS-CoV-2 variants

Researchers recently evaluated the efficacy of the Oxford ChAdOx1 (AZD 1222/ AZD2816) vaccine against the Omicron, Delta, and Beta variants of SARS-CoV-2 in Syrian hamsters.

17 Feb 2022

New Olympus Discovery Center opens to advance human disease research

Olympus is proud to announce the opening of the Olympus Discovery Center at Texas A&M Health to support research focused on treating, alleviating and preventing human diseases.

17 Feb 2022

mRNA-1273 and mRNA-1273.529 Omicron-specific boosters highly effective in mouse model

In a study posted to the bioRxiv* preprint server, a team of researchers from the United States evaluated the protective effect of the preclinical version of the current Moderna Omicron-targeted mRNA-1273.529 vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.529 Omicron infection in mice.

14 Feb 2022

Impact of DNA clearance on mortality in patients with severe COVID-19 infections

In a new study, researchers conducted activity-based proteomic profiling of patients who had severe SARS-CoV-2 infections to understand the impact of DNA clearance on mortality.

28 Jan 2022

Study demonstrates minimally invasive, aerosolized vaccine candidate to combat SARS-CoV-2

This study showed inhalable Covid-19 mimetic particle carriers as potential, versatile, aerosolizable COVID-19 vaccine candidates if worked on with continued optimization and refinement.