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New type of skin patch may provide possible answer to antibiotic resistance crisis

A team of researchers from Queen's University Belfast, led by Professor Ryan Donnelly, Professor of Pharmaceutical Technology are developing a new type of skin patch (microarray patch) that administers drugs directly into the bloodstream through thousands of individual "microneedles" which are being tested as a possible answer to the antibiotic resistance crisis.

5 Jan 2018

Researchers identify mechanism that regulates signaling events leading to cancer metastasis

Understanding how cancer cells are able to metastasize -- migrate from the primary tumor to distant sites in the body -- and developing therapies to inhibit this process are the focus of many laboratories around the country.

18 Dec 2017

Investigating new cancer therapy candidates with live-cell imaging

There are two main things that we've worked on in the lab as regards to drug studies. One is identifying new combinations of drugs, and working on why a combination of drugs should work better than each alone.

From Sartorius 16 Oct 2017

Experts in obstetric care come together to realize quality measures for high-risk pregnancies

The United States spends significantly more money on the delivery of health care yet experiences inferior results. Maternal and infant mortality rates are elevated in the United States as compared to other high-income nations.

11 Oct 2017

Researchers identify potential gonorrhea vaccine candidates

Researchers at Oregon State University have identified a pair of proteins that show promise as the basis for a gonorrhea vaccine.

19 Sep 2017

Native ChIP kit from Chromatrap is now compatible for mass spectrometry

Chromatrap announces that its popular Native ChIP kit is now fully compatible for mass spectrometry (MS) as a downstream process. Combining Chromatrap®’s unique solid-state ChIP technology with MS enables researchers to obtain high quality data sets for chromatin proteomic profiling and mapping of histone modification patterns.

From Chromatrap® - Porvair Sciences Ltd 7 Aug 2017

Researchers explore genetic differences, hereditary factors involved in hemiplegic cerebral palsy

Hemiplegic cerebral palsy hampers movement in one side of a person's body. In the first genetic study of its kind to exclusively focus on those with hemiplegic cerebral palsy, a group of 26 Canadian researchers has investigated the genetic differences and hereditary factors involved in this neurodevelopmental condition.

3 Aug 2017

Study supports genetic testing as first-line diagnostic method for young children with epilepsy

A study published in JAMA Pediatrics supports the use of genetic testing, especially with sequencing, as first-line diagnostic method for young children with seizures.

1 Aug 2017

Could the mTOR pathway be used to protect against cancer?

The mTOR pathway is probably the main pathway in humans and other animals that drives growth. That is, the accumulation of mass and adding mass to make an organism bigger by both making more cells, and making cells grow and become bigger.

22 Jun 2017

Philips introduces new web-based informatics platform to hasten drug research and biomarker discovery

Royal Philips, a global leader in health technology, today announced the launch of its Xplore web-based informatics platform for drug research and biomarker discovery.

From Philips Healthcare 20 Jun 2017

Study uncovers potential new therapeutic targets for HCV infections

An international study led by researchers at Monash University' Biomedicine Discovery Institute (BDI) has shone light on the way the Hepatitis C Virus (HCV) hijacks the communication systems in the host cells it infects, uncovering potential new therapeutic targets for the disease.

8 May 2017

Microarray technology company Arrayjet announces expansion plans

Arrayjet, the Midlothian-based microarray technology company has increased its staffing levels as it continues to expand and grow its international sales development pipeline, as many of the world’s leading university research and biomedical research institutes look to increase accuracy, speed and throughput of its drug discovery sampling using Arrayjet’s range of instrumentation.

3 May 2017

Researchers identify 26 novel genes linked to intellectual disability

Researchers at the Centre for Addiction and Mental Health and Queen's University have identified 26 new genes linked to intellectual disability. Currently most patients with intellectual disability receive no molecular diagnosis, which significantly affects their health and shortens their lifespan.

11 Apr 2017

Genomic Analysis Technologies: Past, Present and Future

In this interview, Jay Flatley, Executive Chairman of Illumina, gives an introduction to Illumina and the next generation genomics tools they provide.

From Pittcon 10 Apr 2017

Linking RNA to autoimmune diseases

An interview with Dr. Chase Spurlock, CEO, discussing IQuity's research into IncRNAs and how they are linked to autoimmue diseases.

20 Mar 2017

Bacterial cell counting and sizing using the Multisizer

In this interview, Dr. Rich Jones introduces bacterial cell counting and an example of when the Multisizer 4e from Beckman Coulter has been used for this application.

From Beckman Coulter Life Sciences - Particle Counting and Characterization 15 Mar 2017

Johns Hopkins researchers find no evidence of CMV in aggressive brain cancer tissues

In a rigorous study of tumor tissue collected from 125 patients with aggressive brain cancers, researchers at Johns Hopkins say they have found no evidence of cytomegalovirus (CMV) infection and conclude that a link between the two diseases, as claimed by earlier reports, likely does not exist.

1 Mar 2017

Novel potassium channel genes could be promising therapeutic targets for alcohol use disorder

A handful of FDA-approved drugs exist for treating individuals with alcohol use disorder but they have been largely ineffective at reducing the high rates of relapse. As such, there remains a critical need to identify and develop alternative pharmacological treatment options.

31 Jan 2017

UAB researchers find how gut fails to prevent HIV-1 infection

The barrier between the gut and the bloodstream is severely damaged in the first few weeks of infection by HIV-1 virus.

28 Jan 2017

Fetal genomic sequencing could enhance detection rate of genetic findings, study shows

In a study to be presented Thursday, Jan. 26, in the oral plenary session at 8 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, researchers with the Columbia University Medical Center in New York found that, in preliminary data, fetal genomic (whole exome) sequencing (WES) as a diagnostic test for women with pregnancies complicated by major fetal congenital anomalies increased the detection rate of genetic findings by between 10 to 30 percent.

23 Jan 2017