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Pathogens drive inflammation by reprogramming host cell metabolic processes

An intestinal pathogen reshapes the gut environment to fuel its own colonization and cause diseases, a multi-institutional team including researchers at Vanderbilt Health has discovered.

30 Apr 2026

Metabolic rewiring could help CAR-T cells fight solid tumors

This review explains how glucose scarcity, lipid disruption, amino acid deprivation, and toxic metabolites weaken CAR-T cells inside solid tumors. It highlights metabolic reprogramming as a promising strategy to improve CAR-T cell persistence, adaptability, and anti-tumor function.

29 Apr 2026

Researchers use light-activated nanozymes to treat aggressive brain tumors

Brain tumors cannot always be successfully treated with conventional therapies. A team from Empa and the hospital network HOCH Health Ostschweiz is therefore developing nanozymes that can attack cancer cells directly in the brain during tumor surgery.

29 Apr 2026

Oxidative stress in aging brain inhibits essential enzymes

Researchers at the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) in Jena found that oxidative stress in the aging brain inhibits the activity of deubiquitylases.

29 Apr 2026

New bioelectronic interface enables long-term vagus nerve stimulation for inflammation

Electrical stimulation of vagus nerve via implantable stimulators can effectively suppress inflammatory responses, offering a novel strategy for treating autoimmune diseases.

29 Apr 2026

Study links socioeconomic stressors to worse pregnancy outcomes for black women

Stresses experienced by black women, such as socioeconomic inequalities, may alter key processes in the body that predispose them to worse pregnancy outcomes than white women, a study by the University of Cambridge has found.

28 Apr 2026

Study identifies protein essential for repairing damage after inflammation

Whenever there is a wound or infection, the body produces an inflammatory response. This is the body's first line of defense, and macrophages — cells of the innate immune system — play a key role: first, they help eliminate pathogens and other infectious agents, and then they trigger the mechanisms that repair the damage caused during the inflammatory process.

28 Apr 2026

Scientists uncover why brain damage continues after stroke

Every stroke begins with a sudden interruption of blood flow in the brain. But what happens afterward—why neurons continue to lose function and die over the following days—has remained one of the most important unanswered questions in neuroscience.

28 Apr 2026

A new biological switch to slow atherosclerosis progression

A study by researchers at Baylor College of Medicine and collaborating institutions reveals a previously unrecognized way blood vessels can protect themselves from damage and slow the development of atherosclerosis. The findings, published in the Proceedings of the National Academy of Sciences, have implications for both vascular precision medicine and the safety of certain emerging cancer treatments.

28 Apr 2026

Noninvasive brain monitoring reveals hidden oxygen deprivation in ICU patients

In neurological intensive care, it is quickly learned that the brain cannot wait. As the most sensitive organ in the human body, it can sustain irreversible damage after just a few minutes of severe hypoxia.

27 Apr 2026

Delayed adrenaline use linked to fatal childhood food anaphylaxis

Fatal delays in administering life-saving adrenaline autoinjector (EpiPen) for food anaphylaxis, a severe and rapid allergic reaction, is highlighted in research being presented at the Royal College of Emergency Medicine Conference today [28 April].

27 Apr 2026

Single protein shapes both brain connectivity and vascular stability

The communication network in the developing brain builds when neurons partner up to form contact points called synapses, allowing signals to pass form one cell to another.

27 Apr 2026

Intercellular heme transfer pathway sustains red blood cell production under stress

Scientists have long been puzzled by how maturing red blood cells manage to produce all the hemoglobin they need to carry oxygen to tissues, even after shedding the vital structures they need to produce it.

25 Apr 2026

Scientists identify STING switch driving inflammation in Alzheimer’s disease

The brain has its own immune system, which detects threats and mounts a defense. A growing body of evidence has shown that in Alzheimer's disease, those immune cells are chronically overactivated, causing inflammation that damages the connections between brain cells.

24 Apr 2026

Trends reveal growing burden of deaths from non-ischemic cardiogenic shock

New data from the CDC WONDER database finds deaths from heart attack-related cardiogenic shock (CS) decreased between 1999 and 2020, but deaths linked to heart failure (HF) and abnormal heart rhythms have risen sharply since 2010, particularly among men.

24 Apr 2026