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Remote pulmonary artery pressure monitoring improves quality of life, reduces heart failure hospitalizations

The first investigator-initiated study of remote pulmonary artery pressure monitoring has found that it improves quality of life and reduces heart failure hospitalizations in patients with chronic heart failure.

22 May 2023

Cross-reactivity between Epstein-Barr virus and protein in multiple sclerosis sheds light on disease development

Research uncovers the association between multiple sclerosis (MS) and antibody reactivity to specific amino acids in CRYAB, along with the increased risk when combined with high EBNA1 responses. The study provides evidence of antibody and T cell cross-reactivity between EBNA1 and CRYAB, highlighting the role of EBV adaptive immune responses in MS development.

21 May 2023

Synthetic delivery vector STxB induces mucosal immunity against viral antigens

Research describes the development of a synthetic delivery vector called STxB for mucosal vaccination. It induces mucosal immunity, including resident memory CD8+ T cells and IgA antibodies, against antigens derived from mucosal viruses when administered intranasally in mice.

21 May 2023

A novel role for macrophage-activation signaling in orchestrating the recruitment process in response to the SARS-CoV-2 spike protein

Researchers derived peptides from the SARS-CoV-2 spike protein to assess COVID-19-associated inflammatory changes using zebrafish models.

19 May 2023

Food preservative nisin: A gut game changer that safely alters microbiome composition

Nisin, a powerful bacteriocin, influences the gut microbiota and its functionality by modulating the abundance of specific bacterial groups and altering short-chain fatty acid synthesis.

18 May 2023

Novel computational platform can expand the pool of cancer immunotherapy targets

Researchers at Children's Hospital of Philadelphia (CHOP) and the University of California, Los Angeles (UCLA) have developed a computational platform capable of discovering tumor antigens derived from alternative RNA splicing, expanding the pool of cancer immunotherapy targets.

17 May 2023

Using synthetic peptides for inflammatory disease diagnosis

Scientists have developed a peptide that binds to the protein calprotectin, a marker of major inflammatory disorders, and shown that it is suitable for diagnostic tests.

17 May 2023

Every breath counts; Utilizing breath biopsy technology to detect disease early

In this interview, we speak to Mariana Leal, Team Lead at Owlstone Medical, about breath biopsies and how they are a useful tool for investigating biomarkers for the early detection of diseases.

From Owlstone Medical Ltd 17 May 2023

"Smart" sutures can detect inflammation and release drugs

Inspired by sutures developed thousands of years ago, MIT engineers have designed "smart" sutures that can not only hold tissue in place, but also detect inflammation and release drugs.

16 May 2023

New compound with antibacterial activity shows promising results within one hour in laboratory trials

Resistance to antibiotics is a problem that alarms the medical and scientific community. Bacteria resistant to three different classes of antibiotics, known as multi-drug resistant (MDR) bacteria, are far from rare.

15 May 2023

New toolkit enables in-vivo cross-linking of protein complexes in live cells

As the executor of life activities, proteins exert their specific biological functions through interactions such as forming protein complexes.

9 May 2023

UCF microbiologist uncovers the evolutionary origins of antimicrobial resistance in bacteria

Bacteria naturally adapt to various environmental stimuli and as they mutate, these changes can make them resistant to drugs that would kill or slow their growth.

5 May 2023

Diet's powerful impact: How gut microbes shape health and battle disease

Research paper discusses the relationship between gut microbiota, diet, and health. It highlights the importance of dietary complex carbohydrates and the potential negative effects of diets high in animal protein and fat on the composition of the microbiota and their metabolic outputs.

4 May 2023

Diet has a much stronger impact on intestinal microbiota than defensins

Researchers at Umeå University, Sweden, have found that among the many factors that shape the intestinal microbiota composition, diet has a much stronger impact than defensins, which are intestinal defence molecules produced by the body.

3 May 2023

A scientific statement from the American Heart and Stroke Association on the prevalence, diagnosis, and management of poststroke cognitive impairment

Researchers reviewed the incidence, prevalence, diagnosis, and management of post-stroke cognitive impairment.

3 May 2023

New approach for efficient engineering of cell and gene therapies

A new approach to the genetic engineering of cells promises significant improvements in speed, efficiency, and reduction in cellular toxicity compared to current methods.

28 Apr 2023

Developing Next-Generation Nanomaterials for Medical Applications

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to Dr. Chad Merkin, Director of the International Institute for Nanotechnology, about his work developing next-generation nanomaterials for medical applications.

From Pittcon 27 Apr 2023

Nanoparticles, mass spectrometry, and more – exploring new avenues for proteomics analysis

In this episode of omg OMx, Bruker's science-driven podcast, Kate Stumpo interviews Daniel Hornburg, the VP of Proteomics at Seer, as they discuss the innovative technologies in plasma proteomics. From nanoparticle-based enrichment to mass spec refinements, they explore how these tools facilitate unbiased, deep, and rapid proteomics.

From Bruker Life Sciences Mass Spectrometry 27 Apr 2023

Researchers identify regions of the viral envelope of simian foamy viruses targeted by neutralizing antibodies

A recent study characterized epitopes recognized by neutralizing antibodies from individuals infected with simian foamy virus.

26 Apr 2023

Mother-child microbiota bond: Transmission shapes future health and development

Research discusses the link between the gut microbiome and health, particularly in early life. It explores the acquisition and transmission of early-life microbiota from mother to child and potential interventions for improving health outcomes.

25 Apr 2023