Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Research uncovers novel predictors of immune checkpoint inhibitor therapy for melanoma

Immune checkpoint inhibitor (ICI) therapy is a type of treatment for melanoma, the deadliest form of skin cancer, which blocks proteins on tumor or immune cells that prevent the immune system from killing cancer cells.

19 Sep 2022

Aerobic exercise training shows potential to restore function in individuals with thalamic atrophy

Thalamic atrophy needs to be considered in clinical studies of the functional abilities of individuals with multiple sclerosis, according to findings reported by a team of experts.

16 Sep 2022

Novel imaging information system may provide a faster, more accurate prognosis for certain cancers

Researchers at the University of Colorado Anschutz Medical Campus have found that a new imaging information system may ultimately provide a faster, more accurate prognosis for certain cancers.

16 Sep 2022

Defensosomes versus COVID-19

In a recent study published in the journal PLoS Biology, researchers investigated the role of angiotensin-converting enzyme 2 (ACE2)-containing defensive exosomes, or 'defensosomes' against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

14 Sep 2022

Study highlights role of tumor-infiltrating B cells, plasma cells in cancer development and treatment outcomes

Through extensive single-cell analysis, researchers at The University of Texas MD Anderson Cancer Center have created a spatial map of tumor-infiltrating B cells and plasma cells in early-stage lung cancers, highlighting previously unappreciated roles these immune cells play in tumor development and treatment outcomes.

13 Sep 2022

HSD3B1 gene holds clues for predicting and treating endometrial cancer

The HSD3B1 gene could hold clues for predicting and treating endometrial cancer, according to a novel finding from the Cleveland Clinic's Lerner Research Institute.

13 Sep 2022

Study identifies new therapeutic target against lung adenocarcinoma

The TIMP-1 protein levels in both tissues and blood have been repeatedly associated with a poor prognosis in lung cancers, but its role in this cancer process was, to date, unknown.

12 Sep 2022

Label-free trace detection of bio-molecules by LI-SERS method

A new publication from Opto-Electronic Advances; DOI 10.29026/oea.2022.210121 discusses label-free trace detection of bio-molecules by liquid-interface assisted surface-enhanced Raman scattering using a microfluidic chip.

9 Sep 2022

Gut microbes can also impact a person's neurological and emotional health, UTSW researcher says

The role of the microbiome in intestinal and systemic health has garnered close attention among researchers for many years.

9 Sep 2022

Using Q-bodies for imaging intracellular proteins in live cells

Recent advances in imaging technology have made it possible to visualize intracellular dynamics, which offers a better understanding of several key biological principles for accelerating therapeutic development.

9 Sep 2022

Study provides a potential game-changer in assessing treatment response in pancreatic cancer patients

The statistics for pancreatic cancer are sobering. With a five-year survival rate of only 9%, incidence of the most common type, pancreatic ductal adenocarcinoma (PDAC), is growing and projected to be the second cause of cancer deaths by 2030.

8 Sep 2022

The role of some important antioxidants in major clinical outcomes of subjects with COVID-19

Researchers investigated the role of antioxidants such as selenium, zinc, α-lipoic acid, and vitamins A, E, D, and C in improving the clinical outcomes of COVID-19.

8 Sep 2022

Research identifies a promising path to developing therapies to treat esophageal tumors

Research led by Case Western Reserve University has identified a promising path to developing therapies to treat esophageal tumors––a form of cancer that not only is among the most deadly, but also has been occurring at increasing rates over the past decade.

8 Sep 2022

Studies to explore whether achieving beneficial ketone levels can improve metabolic health of military service members

A series of upcoming studies will explore whether the grind of active-duty military life and veterans' disproportionately high incidence of chronic illness could be tamed by lifestyle interventions designed to achieve a metabolic state of nutritional ketosis.

7 Sep 2022

Persistent cardiac symptoms in individuals with mild initial COVID-19

In a recent study published in the journal Nature Medicine, researchers conducted serial cardiac assessments in individuals with mild initial coronavirus disease 2019 (COVID-19) who had no history of cardiac disease and significant comorbidities.

7 Sep 2022

Metabolic signature could be a potential target for new breast cancer therapies

Despite advancements in cancer detection and treatment, breast cancer that comes back or spreads still presents a challenge to researchers and oncologists.

6 Sep 2022

Alternative approaches to functional and phenotypic assays using multi-parameter flow cytometry

Synexa is an industry-leading biomarker and large molecule bio analytic research service provider. In this interview, NewsMedical speaks with Natalie Strickland, a principal scientist at Synexa, about alternative approaches to flow cytometry.

From Synexa Life Sciences 5 Sep 2022

Simple blood test may identify patients at high risk of neurotoxic complications after CAR-T cell therapy

Cell-based immunotherapy called CAR-T cell therapy has revolutionized the treatment of several cancers.

1 Sep 2022

Brain activity patterns during sleep shed light on the neurobiology behind 22q11.2 Deletion Syndrome

The brain activity patterns during sleep shed light on the neurobiology behind a genetic condition called 22q11.2 Deletion Syndrome (22q11.2DS) and could be used as a biomarker to detect the onset of neuropsychiatric disorders in people with 22q11.2DS.

30 Aug 2022

EEG tests reveal fentanyl's effects on the brain

Fentanyl is used to supplement sedation and to relieve severe pain during and after surgery, but it's also one of the deadliest drugs of the opioid epidemic.

30 Aug 2022

Biomarker News and Research

Further Reading

Research uncovers novel predictors of immune checkpoint inhibitor therapy for melanoma

Aerobic exercise training shows potential to restore function in individuals with thalamic atrophy

Novel imaging information system may provide a faster, more accurate prognosis for certain cancers

Defensosomes versus COVID-19

Study highlights role of tumor-infiltrating B cells, plasma cells in cancer development and treatment outcomes

HSD3B1 gene holds clues for predicting and treating endometrial cancer

Study identifies new therapeutic target against lung adenocarcinoma

Label-free trace detection of bio-molecules by LI-SERS method

Gut microbes can also impact a person's neurological and emotional health, UTSW researcher says

Using Q-bodies for imaging intracellular proteins in live cells

Study provides a potential game-changer in assessing treatment response in pancreatic cancer patients

The role of some important antioxidants in major clinical outcomes of subjects with COVID-19

Research identifies a promising path to developing therapies to treat esophageal tumors

Studies to explore whether achieving beneficial ketone levels can improve metabolic health of military service members

Persistent cardiac symptoms in individuals with mild initial COVID-19

Metabolic signature could be a potential target for new breast cancer therapies

Alternative approaches to functional and phenotypic assays using multi-parameter flow cytometry

Simple blood test may identify patients at high risk of neurotoxic complications after CAR-T cell therapy

Brain activity patterns during sleep shed light on the neurobiology behind 22q11.2 Deletion Syndrome

EEG tests reveal fentanyl's effects on the brain

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

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