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Study reveals a disease-relevant role for tanycytes in neurodegeneration

Accumulation of the protein tau in the brain is one of the hallmarks of Alzheimer's disease. In a paper publishing March 5 in the Cell Press journal Cell Press Blue, researchers report a previously unknown mechanism that appears to enable the build-up of tau.

5 Mar 2026

Targeted mRNA delivery restores sperm production and fertility in infertile mice

Researchers have found that targeted delivery of messenger RNA (mRNA) can restore sperm production and fertility in genetically infertile male mice.

5 Mar 2026

Teenage aggression linked to faster biological aging and health risks later in life

Teens who frequently lash out at others may face lasting physical health consequences later in life, according to research published by the American Psychological Association.

5 Mar 2026

Tufts researchers identify new vulnerabilities to combat persistent C. diff infections

Affecting roughly half a million Americans each year, bacterial infections caused by Clostridioides difficile—commonly known as C. diff—are a serious and persistent problem for patients and hospitals alike.

5 Mar 2026

Distinct spatial tumor–immune ecosystems predict lung cancer treatment response

Researchers at Moffitt Cancer Center have identified distinct spatial tumor–immune ecosystems that predict whether patients with advanced non–small cell lung cancer will benefit from immunotherapy.

5 Mar 2026

New AstroID database integrates clinical and genetic data for large-scale cancer studies

Researchers from the Johns Hopkins Kimmel Cancer Center and The Johns Hopkins University have created a novel database structure that allows investigators anywhere to more easily study multiple types of cancer data - including laboratory results, genetic sequencing and imaging data - in one setting.

5 Mar 2026

Copper metabolism identified as a new therapeutic target for inflammatory osteolysis

Inflammatory osteolysis is a condition involving progressive bone tissue destruction and is observed in many well-known skeletal disorders, including rheumatoid arthritis, osteoporosis, and chronic apical periodontitis.

5 Mar 2026

No evidence probiotic skincare can improve mood

Current findings reveal no support for emotional benefits from probiotic cosmetics, highlighting the need for further investigation into neurocosmetics.

5 Mar 2026

Long COVID taste loss tied to reduced expression of key taste genes

The study identifies molecular changes in taste receptor cells as a potential cause of persistent taste dysfunction in long COVID-19, impacting quality of life.

5 Mar 2026

AI pinpoints why vaccine responses vary globally

How people with compromised immune systems respond to vaccines is an important area of immunological research. A new study led by York University found that not only could machine-learning models accurately pinpoint differences in healthy controls and those living with HIV, but also found outliers in both groups that provide fascinating glimpses into the complex nature of the immune system and what personalized medicine could look like in the future, accounting for variables such as age, comorbidities and genetics.

4 Mar 2026

Advancing influenza vaccine development: Sino Biological launches antigens for the 2026-2027 Northern Hemisphere influenza vaccine strains

The World Health Organization (WHO) has announced its recommendations for the 2026–2027 Northern Hemisphere influenza vaccine composition.

From Sino Biological Inc. 4 Mar 2026

Experimental therapy dramatically reduces seizures in children with Dravet syndrome

A new experimental treatment for children with a hard-to-treat form of epilepsy is safe and can reduce seizures dramatically, helping them lead much healthier and happier lives, the findings of a UCL and Great Ormond Street Hospital-led international clinical trial show.

4 Mar 2026

New fragmentome technology can detect early liver fibrosis and cirrhosis

Researchers at the Johns Hopkins Kimmel Cancer Center report that an artificial intelligence (AI)-based liquid biopsy test using genome-wide cell-free DNA (cfDNA) fragmentation patterns and repeat landscapes can detect early liver fibrosis and cirrhosis, and may also reveal signals of broader chronic disease burden.

4 Mar 2026

Armored CAR T cells overcome tumor defenses in solid cancers

UCLA scientists have developed a next-generation CAR-T cell therapy that can overcome the immunosuppressive tumor microenvironment, a protective shield that tumors use to weaken immune cells, block their attack and fuel tumor growth.

4 Mar 2026

Nearly 70 weeks after infection, long COVID patients show no detectable inflammation in blood tests

A controlled Norwegian case-control study examined circulating biomarkers of inflammation and neuronal injury in people with long COVID about 69 weeks after infection. The researchers found no significant differences in systemic inflammatory or neuroinjury markers compared with recovered controls after statistical correction.

4 Mar 2026

Cell News and Research

Study reveals a disease-relevant role for tanycytes in neurodegeneration

Targeted mRNA delivery restores sperm production and fertility in infertile mice

Teenage aggression linked to faster biological aging and health risks later in life

Tufts researchers identify new vulnerabilities to combat persistent C. diff infections

Distinct spatial tumor–immune ecosystems predict lung cancer treatment response

New AstroID database integrates clinical and genetic data for large-scale cancer studies

Copper metabolism identified as a new therapeutic target for inflammatory osteolysis

No evidence probiotic skincare can improve mood

Long COVID taste loss tied to reduced expression of key taste genes

AI pinpoints why vaccine responses vary globally

Advancing influenza vaccine development: Sino Biological launches antigens for the 2026-2027 Northern Hemisphere influenza vaccine strains

Experimental therapy dramatically reduces seizures in children with Dravet syndrome

New fragmentome technology can detect early liver fibrosis and cirrhosis

Armored CAR T cells overcome tumor defenses in solid cancers

Nearly 70 weeks after infection, long COVID patients show no detectable inflammation in blood tests

Enhancing myelination may help sustain therapeutic effects of psychedelic-assisted PTSD treatment

Dietary fat ratios impact the strength of immune cells and ability to fight disease

Study sheds light on potential therapeutic strategies for post-traumatic osteoarthritis

3D-printed scaffolds use shape memory to heal infected bone defects

Periodontal bacteria trigger bone density reduction via the gut

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Evaluating new approaches for rare disease genomics

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