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KAIST scientists achieve first total synthesis of herpotrichone with neuroprotective properties

"Herpotrichone" is a natural substance that has been evaluated highly for its excellent ability to suppress inflammation in the brain and protect nerve cells, displaying significant potential to be developed as a therapeutic agent for neurodegenerative brain diseases such as Alzheimer's disease and Parkinson's disease.

5 Aug 2025

Scaling organ‑chip technology for human‑relevant drug discovery

Discover how AVA brings scale and reproducibility to organ‑chip technology, enabling human‑relevant insights that accelerate drug discovery workflows.

From Emulate, Inc. 5 Aug 2025

Breakthrough study reveals potential treatment path for ALS

Amyotrophic lateral sclerosis (ALS), known as Lou Gehrig's disease, is an incurable neurological disorder affecting motor neurons-nerve cells in the brain and spinal cord that control voluntary muscle movement and breathing.

5 Aug 2025

The Microsphere Summit is Back

Attend the 2025 Microsphere Summit to connect with leaders in drug delivery and manufacturing, focusing on particle size control and therapeutic advancements.

From Powder Systems 5 Aug 2025

'Two-in-one' RNA molecule can simultaneously turn off two difficult-to-target cancer-related genes

University of North Carolina Lineberger Comprehensive Cancer Center researchers have developed a "two-in-one" molecule that can simultaneously turn off two notoriously difficult-to-target cancer-related genes, KRAS and MYC, as well as directly deliver drugs to tumors that express these genes.

4 Aug 2025

New treatment approach developed to prevent lupus nephritis

At the time when patients with lupus, or systemic lupus erythematosus (SLE), are diagnosed, approximately 15% to 30% will already have the inflammation-caused kidney disease lupus nephritis, which compromises kidney function and can lead to kidney failure.

4 Aug 2025

Natural brain rhythms control stress hormone levels and alertness

Ōtākou Whakaihu Waka-led research has found stress-controlling brain cells switch on and off in a steady rhythm about once every hour – even when nothing stressful is happening.

4 Aug 2025

McGill researchers develop digital tool to reduce unnecessary medication use

McGill University researchers have developed and are licensing a digital tool to help safely reduce patients' use of medications that may be unnecessary or even harmful to them.

4 Aug 2025

Advancing healthcare with machine learning and big data at Cedars-Sinai

Two new studies from the Department of Computational Biomedicine at Cedars-Sinai are advancing what we know about using machine learning and big data to improve healthcare and medical research.

4 Aug 2025

Understanding the importance of B vitamins for health

Eight different vitamins make up the B complex, and they all play crucial roles in the body, such as producing energy, keeping our nervous system healthy, and supporting cell development.

4 Aug 2025

Psychedelic and non-hallucinogenic drugs promote neuroplasticity through shared pathways

Understanding exactly how psychedelics promote new connections in the brain is critical to developing targeted, non-hallucinogenic therapeutics that can treat neurodegenerative and neuropsychiatric diseases.

4 Aug 2025

New drug combo outperforms Tamiflu in fighting deadliest flu strains

A surprising new drug combo—including a compound found in chocolate—has outperformed Tamiflu in fighting the flu, according to a study published in PNAS.

4 Aug 2025

New research unveils vast influence of B vitamins on health and disease

Eight essential nutrients make up the suite of B vitamins also known as the B complex. Researchers from Tufts University and elsewhere have revealed that these B vitamins influence a vast spectrum of human health and disease, including cognitive function, cardiovascular health, gastric bypass recovery, neural tube defects, and even cancer.

4 Aug 2025

Mapping the brain’s serotonin switch could lead to better antidepressants

In a discovery that could guide the development of next-generation antidepressants and antipsychotic medications, researchers at the Icahn School of Medicine at Mount Sinai have developed new insights into how a critical brain receptor works at the molecular level and why that matters for mental health treatments.

1 Aug 2025

Study uncovers inflammatory pathways that contribute to asthma flare-ups in children

A recent multicenter clinical trial has uncovered inflammatory pathways that contribute to asthma flare-ups in children that occur despite treatment, according to findings published in JAMA Pediatrics.

1 Aug 2025

Narrow Medicare drug coverage linked to worse outcomes in MS patients

Medicare drug plans are increasingly excluding coverage of new specialty drugs that treat complex conditions like cancers and autoimmune diseases. New research from the USC Schaeffer Center shows how these barriers may come at a cost to patients' health.

1 Aug 2025

Unlocking the power of stereochemistry to improve mRNA drug delivery

A team from the Max-Planck-Institut für Kohlenforschung, Hokkaido University, and Osaka University has discovered that subtle differences in molecular structure can have a major impact on the performance of mRNA-based drugs.

1 Aug 2025

Deadly opioid contaminants uncovered in Adelaide street drug supply

A synthetic opioid 1000 times more potent than morphine is infiltrating the street drug trade in Adelaide, Australia, sparking fears of a wave of overdoses that could be lethal.

1 Aug 2025

Synthetic torpor moves closer to real-world medical use

Nature is often the best model for science. For nearly a century, scientists have been trying to recreate the ability of some mammals and birds to survive extreme environmental conditions for brief or extended periods by going into torpor, when their body temperature and metabolic rate drop, allowing them to preserve energy and heat.

1 Aug 2025

Study finds rapid spread of antibiotic-resistant bacteria among malnourished children in Niger

A new study led by researchers at the Ineos Oxford Institute for antimicrobial research (IOI) has found that antimicrobial resistant bacteria is spreading rapidly among children being treated for severe malnutrition in a hospital facility in Niger.

1 Aug 2025