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Electric fans ease heart strain for older adults in humid heat

New collaborative research from the University of Sydney and the Montreal Heart Institute has shown that using a fan in hot and humid weather reduces cardiac strain in older people, contradicting recommendations from the Centers of Disease Control and Prevention in the US.

6 Nov 2024

Researchers uncover immune mechanism behind myocarditis from cancer immunotherapy

Some patients being treated with immune checkpoint inhibitors, a type of cancer immunotherapy, develop a dangerous form of heart inflammation called myocarditis.

6 Nov 2024

A novel synthetic lethal target for ATM inhibitors in pancreatic cancer

A novel discovery in the field of pancreatic cancer treatment has been unveiled, revealing the epigenetic silencing of BEND4 as a potential synthetic lethal marker for enhancing the efficacy of ATM inhibitors in pancreatic cancer treatment.

5 Nov 2024

Curcumin compound reactivates Epstein–Barr virus, offering safer cancer therapy

A novel curcumin derivative, C210, activates the Epstein–Barr virus (EBV) lytic cycle without producing infectious virions by disrupting HSP90. This discovery opens avenues for safer EBV-positive cancer therapies.

5 Nov 2024

New active substance shows promise in treating acute sudden hearing loss

A research team led by MedUni Vienna has investigated AC102, a new active substance that offers hope of an effective treatment for acute sudden hearing loss. The latest results have been published in the scientific journal "Cell Death & Disease".

5 Nov 2024

Modulating CD39 expression to enhance CAR-T cell therapy against hepatocellular carcinoma

In the quest to enhance the efficacy of chimeric antigen receptor T (CAR-T) cell therapy against hepatocellular carcinoma (HCC), a recent study has identified a pivotal role for CD39 expression in modulating the function of CAR-T cells.

5 Nov 2024

Lupus Research Alliance announces 33 studies to be presented at ACR Convergence 2024

The Lupus Research Alliance (LRA), the largest private funder of lupus research worldwide, today announced that a total of 33 studies, funded by the organization or supported by its clinical research affiliate Lupus Therapeutics, will be presented at ACR Convergence 2024.

5 Nov 2024

Researchers develop the first polymer-based therapeutic for Huntington’s disease

Breakthrough polymer-based therapy shows promise in reversing Huntington's disease symptoms by preventing toxic protein clumps and enhancing neuronal survival.

4 Nov 2024

Weight loss drug semaglutide may offer relief for knee arthritis pain

Semaglutide shows promise in treating knee osteoarthritis by reducing pain and weight, offering a safe alternative to traditional pharmacological interventions.

4 Nov 2024

New pathway discovery explains MRSA's high-level antibiotic resistance

Researchers have discovered a new cell division pathway in MRSA that enables high-level resistance to β-lactam antibiotics, marking a critical insight into the persistence of these 'superbugs'.

3 Nov 2024

Iron supplements may boost brain development in children with HIV

A University of Minnesota Medical School research team has found that giving iron supplements to children living with human immunodeficiency virus (HIV) in sub-Saharan Africa could be an important first step in optimizing brain development.

1 Nov 2024

Acupuncture shows promise in alleviating symptoms of chronic irritable bowel syndrome

A recent randomized controlled trial has shed light on the efficacy of acupuncture as a treatment for refractory irritable bowel syndrome (IBS), a chronic gastrointestinal disorder that significantly impacts quality of life and often resists conventional treatment.

1 Nov 2024

Can olfactory loss predict disease? Study ties loss of smell to 139 health conditions

Olfactory dysfunction links to 139 conditions, with inflammation playing a key role in memory decline and cognitive issues. Olfactory enrichment shows promise.

1 Nov 2024

Transcranial ultrasound stimulation: A new frontier in noninvasive brain therapy

Transcranial ultrasound stimulation combines accuracy and reversibility, paving the way for innovative treatments of neurological and psychiatric disorders.

1 Nov 2024

New therapeutic target overcomes ovarian cancer immunotherapy resistance

Researchers at the Icahn School of Medicine at Mount Sinai have discovered a way that ovarian cancer tumors manipulate their environment to resist immunotherapy and identified a drug target that could overcome that resistance.

1 Nov 2024

VALANX Biotech and Fina Biosolutions Introduce ClickCRM for Rapid Conjugate Vaccine Development

VALANX Biotech (VALANX), a biotech company developing novel technology for site-specific protein conjugation in drug and diagnostics discovery, and Fina Biosolutions LLC (FinaBio), experts in conjugate vaccine development and conjugate chemistry, today announced the signing of a joint IP and licensing agreement.

From VALANX Biotech 31 Oct 2024

Semaglutide reduces urine albumin-to-creatinine ratio in overweight chronic kidney disease patients

Researchers investigate the clinical efficacy of semaglutide in controlling urine albumin-to-creatinine ratio in overweight patients with chronic kidney disease.

31 Oct 2024

Study reveals cost-effective benefits of treating depression in low-income countries

Treating people in low-income countries for major depressive disorder can also help improve their physical health and household members' wellbeing, demonstrating that mental health treatments can be cost effective, according to a new RAND study.

30 Oct 2024

Study finds nirmatrelvir-ritonavir reduces severe COVID-19 and long COVID risks in high-risk patients

Nirmatrelvir-ritonavir effectively lowers hospitalization rates and long COVID symptoms in non-hospitalized, high-risk patients with mild to moderate COVID-19.

30 Oct 2024

Drug repurposing offers hope for SYNGAP1 patients

The SynGAP Research Fund 501(c)(3) has awarded a pair of grants to Dr. Clement Chow, a geneticist and Associate Professor in the Department of Human Genetics at the University of Utah. These grants are crucial steps in advancing therapeutic development for SYNGAP1-Related Disorders (SRD).

30 Oct 2024

Efficacy News and Research

Electric fans ease heart strain for older adults in humid heat

Researchers uncover immune mechanism behind myocarditis from cancer immunotherapy

A novel synthetic lethal target for ATM inhibitors in pancreatic cancer

Curcumin compound reactivates Epstein–Barr virus, offering safer cancer therapy

New active substance shows promise in treating acute sudden hearing loss

Modulating CD39 expression to enhance CAR-T cell therapy against hepatocellular carcinoma

Lupus Research Alliance announces 33 studies to be presented at ACR Convergence 2024

Researchers develop the first polymer-based therapeutic for Huntington’s disease

Weight loss drug semaglutide may offer relief for knee arthritis pain

New pathway discovery explains MRSA's high-level antibiotic resistance

Iron supplements may boost brain development in children with HIV

Acupuncture shows promise in alleviating symptoms of chronic irritable bowel syndrome

Can olfactory loss predict disease? Study ties loss of smell to 139 health conditions

Transcranial ultrasound stimulation: A new frontier in noninvasive brain therapy

New therapeutic target overcomes ovarian cancer immunotherapy resistance

VALANX Biotech and Fina Biosolutions Introduce ClickCRM for Rapid Conjugate Vaccine Development

Semaglutide reduces urine albumin-to-creatinine ratio in overweight chronic kidney disease patients

Study reveals cost-effective benefits of treating depression in low-income countries

Study finds nirmatrelvir-ritonavir reduces severe COVID-19 and long COVID risks in high-risk patients

Drug repurposing offers hope for SYNGAP1 patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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