Fasting News and Research

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Fatty liver disease medication may have no effect

A new randomized, prospective trial has shown that orlistat, a commonly prescribed inhibitor of fat absorption, does not help patients with fatty liver disease (FLD) lose weight, nor does it improve their liver enzymes or insulin resistance.

13 Jan 2009

Lilly receives complete response letter for Olanzapine LAI for treatment of schizophrenia

Eli Lilly and Company has announced that it received a complete response letter from the U.S. Food and Drug Administration (FDA) for olanzapine long-acting injection (LAI) for acute and maintenance treatment of schizophrenia in adults.

7 Jan 2009

High-fat diet can disrupt our biological clock

Indulgence in a high-fat diet can not only lead to overweight because of excessive calorie intake, but also can affect the balance of circadian rhythms - everyone's 24-hour biological clock, Hebrew University of Jerusalem researchers have shown.

29 Dec 2008

deCODE to integrate new genetic risk factor for type 2 diabetes into its personal genome scan service

deCODE genetics has announced the discovery by an international consortium of scientists from deCODE and major European and US academic institutions of a single letter variation in the human genome (SNP) that is associated with increased fasting glucose levels and risk of type 2 diabetes (T2D).

8 Dec 2008

Body clock and sleep patterns linked to diabetes and high blood sugar

Diabetes and high levels of blood sugar may be linked to abnormalities in a person's body clock and sleep patterns, according to a genome-wide association study published today in the journal Nature Genetics.

7 Dec 2008

New clinical tool to identify those at highest risk for having undetected hyperglycemia

A third of Americans with diabetes do not know that they have it, and many more who have prediabetic conditions are unaware that they are at risk.

5 Dec 2008

Adropin protein produced by the liver sends signal that fat is on the way in response to high-fat foods

After you eat a burger and fries or other fat-filled meal, a protein produced by the liver may send a signal that fat is on the way, suggests a report in the December issue of the journal Cell Metabolism , a Cell Press publication.

3 Dec 2008

A potential new procedure for treating obesity

Lining the upper portion of the small intestine with an impermeable sleeve led to both weight loss and restoration of normal glucose metabolism in an animal model of obesity-induced diabetes.

24 Nov 2008

Eating too many eggs may raise your risk of type 2 diabetes

According to new research from the U.S. eating too many eggs may increase the risk of a person developing type 2 diabetes - and this applies to both men and women.

24 Nov 2008

Metabolex announces positive results from phase 2 trial of MBX-8025

The Phase 2 study was a randomized, double-blind, placebo-controlled clinical trial evaluating the safety and efficacy of MBX-8025, both alone and in combination with atorvastatin (marketed as Lipitor(R)), over an 8-week treatment period.

19 Nov 2008

Staying active may lower health risks for large, retired athletes

The larger body size of professional football players doesn't increase risk of cardiovascular disease or atherosclerosis after they retire, according to research presented at the American Heart Association's Scientific Sessions 2008.

12 Nov 2008

Elevated nonfasting triglyceride levels linked with higher risk of stroke

Elevated nonfasting triglyceride levels, previously associated with an increased risk for heart attack, also appear to be associated with an increased risk for ischemic stroke, according to a study in the November 12 issue of JAMA.

11 Nov 2008

Latest glaucoma research

Glaucoma-related highlights of today's scientific program of the 2008 Joint Meeting of the American Academy of Ophthalmology (Academy) and European Society of Ophthalmology (SOE) include a study that correlates optic nerve damage in glaucoma patients with carotid artery narrowing and potentially elevated risk for stroke, and a survey that looks at how the practice of fasting, common to the world's seven major religions, may affect patient compliance with treatment for glaucoma and other eye diseases.

10 Nov 2008

New clinical guidelines on prevention of cardiovascular disease and diabetes in patients at highest risk

The Endocrine Society has released a new clinical practice guideline for the primary prevention of cardiovascular disease and type 2 diabetes in patients at metabolic risk.

7 Nov 2008

New drug tricks the body into burning off fat

French scientists have found a drug they say tricks the body into burning off fat - and it even works on a high-fat diet.

5 Nov 2008

New weapon in the fight against obesity and diabetes

A study appearing November 5 in the journal Cell Metabolism demonstrates that a synthetic new chemical entity protects against diet-induced obesity, improves glucose tolerance and insulin sensitivity and enhances exercise endurance by enhancing fat utilization in certain target tissues.

4 Nov 2008

Scientists discover a catalytic antibody that degrades a known appetite stimulant

The antibody works against the gastric hormone ghrelin (pronounced "grell-in"), which has been linked to weight gain and fat storage through its metabolic actions. These findings point towards a potentially novel treatment for obesity that would interfere directly with the some of the biological mechanisms determining weight.

28 Oct 2008