Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

Study: HUCBs boost survival and maturation of hippocampal neurons

Laboratory culture studies examining the activity of human umbilical cord blood cells on experimental models of central nervous system aging, injury and disease, have shown that HUCBs provide a 'trophic effect' that enhances survival and maturation of hippocampal neurons harvested from both young and old laboratory animals.

15 Dec 2010

Is neuroimaging voodoo, new phrenology, or scientific breakthrough

Neuroimaging-is it voodoo, new phrenology, or scientific breakthrough? See what the experts have to say in this special section on fMRI in Perspectives on Psychological Science.

9 Dec 2010

New study shows how meditators don't ponder pain

Zen meditation has many health benefits, including a reduced sensitivity to pain. According to new research from the Universit- de Montr-al, meditators do feel pain but they simply don't dwell on it as much. These findings, published in the month's issue of Pain, may have implications for chronic pain sufferers, such as those with arthritis, back pain or cancer.

9 Dec 2010

Low-dose diazepam with NS-398 combination has twice the neuroprotective effect of NS-398 alone

Status epilepticus, prolonged seizures, can lead to significant neurological deficits and, rarely, even death. The anticonvulsant diazepam, a first line therapy for the condition, is neuroprotective when administered in high doses within two hours from seizure onset. Researchers at the 64th AES Annual Meeting now report that the combination of low-dose diazepam and NS-398, a COX-2 inhibitor, has twice the neuroprotective effect of NS-398 alone.

8 Dec 2010

Researchers develop new drugs to prevent post-traumatic stress syndrome

Post-traumatic stress syndrome - when a severely stressful event triggers exaggerated and chronic fear - affects nearly 8 million people in the United States and is hard to treat. In a preclinical study, Northwestern Medicine scientists have for the first time identified the molecular cause of the debilitating condition and prevented it from occurring by injecting calming drugs into the brain within five hours of a traumatic event.

7 Dec 2010

Exposure to nicotine during pregnancy may cause learning disabilities in children: Research

Exposure to nicotine during pregnancy leads to a decrease in adult stem cells and a change in synaptic plasticity in the hippocampus of the offspring, according to new research from the University of Alabama at Birmingham presented at Neuroscience 2010, the annual Society for Neuroscience meeting in San Diego in November.

4 Dec 2010

Chronic jet lag alters brain's intricate role in memory processing

Chronic jet lag alters the brain in ways that cause memory and learning problems long after one's return to a regular 24-hour schedule, according to research by University of California, Berkeley, psychologists.

25 Nov 2010

Researchers document novel form of splicing in nerve cell cytoplasm

Cells have their own version of the cut-and-paste editing function called splicing. Researchers at the University of Pennsylvania School of Medicine have documented a novel form of splicing in the cytoplasm of a nerve cell, which dictates a special form of a potassium channel protein in the outer membrane.

19 Nov 2010

Study finds association between personality, cognitive ability and neuroendocrinal dysfunction in exhaustion syndrome

Exhaustion syndrome, also called burnout and exhaustion depression, leaves objectively measurable changes in the brain including reduced activity in the frontal lobes and altered regulation of the stress hormone cortisol. This is shown in a new dissertation from Umeå University in Sweden.

18 Nov 2010

Dim light at night linked to depression

Exposure to even dim light at night is enough to cause physical changes in the brains of hamsters that may be associated with depression, a new study shows.

18 Nov 2010

Special glasses to spot people at risk for PTSD

Around 30 percent of people surviving a traumatic event, such as a serious car crash, will go on to develop Post Traumatic Stress Disorder (PTSD). Doctors don't know who is susceptible and treating people who don't have PTSD can make things worse. However, new research by psychologist Dr Peter Naish, of the Open University, and his colleague Dr Ksenja da Silva, may help.

18 Nov 2010

Neuralstem files NSI-189 IND with FDA for Phase I safety trials for major depression

Neuralstem, Inc. announced that it has filed an Investigational New Drug (IND) application with the United States Food and Drug Administration (FDA) to begin two Phase I safety trials to test NSI-189, its first small molecule compound, for the treatment of major depression. NSI-189 is a proprietary new chemical entity discovered by Neuralstem that stimulates new neuron growth in the hippocampus, an area of the brain that is believed to be involved in depression.

18 Nov 2010

5-lipoxygenase protein modulates amyloid beta formation linked to Alzheimer's disease

A protein known to exist in the brain for more than 30 years, called 5-lipoxygenase, has been found to play a regulatory role in the formation of the amyloid beta in the brain, the major component of plaques implicated in the development of Alzheimer's disease, according to researchers at Temple University's School of Medicine.

18 Nov 2010

New findings help identify impact of prenatal environment on early parental care on brain

New findings released today help identify the long-term impact of the prenatal environment and early parental care on the brain. Using animals as models, researchers help explain why early inflammation and a mother's exposure to drugs such as nicotine and high doses of pain killers have lasting consequences for children and even future generations.

16 Nov 2010

Size of hippocampus may be linked to early dementia

The size of the part of the brain known as the hippocampus may be linked to future dementia, reveals a thesis from the University of Gothenburg, Sweden.

16 Nov 2010

Researchers find structural deficits in gray matter may be associated with daytime sleepiness

Patients with obstructive sleep apnea (OSA) may blame their daytime difficulties on simple sleepiness, but new research suggests that their brains may be to blame. Specifically, their cognitive challenges may be caused by structural deficits in gray matter, brought on by the intermittent oxygen deprivation that comes with OSA. The good news is that these deficits may be partially or fully reversible with early detection and treatment, according to Italian researchers

15 Nov 2010

Early interference in entorhinal cortex may halt progression of Alzheimer's disease

New research is helping to unravel the events that underlie the "spread" of Alzheimer's disease (AD) throughout the brain. The research, published by Cell Press in the November 4th issue of the journal Neuron, follows disease progression from a vulnerable brain region that is affected early in the disease to interconnected brain regions that are affected in later stages. The findings may contribute to design of therapeutic interventions as targeting the brain region where AD originates would be simpler than targeting multiple brain areas.

4 Nov 2010

Scientists identify events that causes AD progression

Scientists at the Gladstone Institute of Neurological Disease (GIND) have offered new information about the events that underlie the "spread" of Alzheimer's disease (AD) throughout the brain.

4 Nov 2010

Study reveals a potential target for treating brain trauma

Brain damage continues to develop and evolve for months after a traumatic brain injury (TBI), revealing a potential target for treatments to improve brain trauma, new research led by the University of Melbourne, Australia has found.

3 Nov 2010

Molecular imaging technique pinpoints changes that take place in injured brain

Results from a study published in the November issue of The Journal of Nuclear Medicine (JNM) show that powerful imaging techniques positron emission tomography (PET) fused with magnetic resonance imaging (MRI) are helping researchers better understand the long-term functional and structural changes that take place after traumatic brain injury (TBI).

2 Nov 2010

Hippocampus News and Research

Further Reading

Study: HUCBs boost survival and maturation of hippocampal neurons

Is neuroimaging voodoo, new phrenology, or scientific breakthrough

New study shows how meditators don't ponder pain

Low-dose diazepam with NS-398 combination has twice the neuroprotective effect of NS-398 alone

Researchers develop new drugs to prevent post-traumatic stress syndrome

Exposure to nicotine during pregnancy may cause learning disabilities in children: Research

Chronic jet lag alters brain's intricate role in memory processing

Researchers document novel form of splicing in nerve cell cytoplasm

Study finds association between personality, cognitive ability and neuroendocrinal dysfunction in exhaustion syndrome

Dim light at night linked to depression

Special glasses to spot people at risk for PTSD

Neuralstem files NSI-189 IND with FDA for Phase I safety trials for major depression

5-lipoxygenase protein modulates amyloid beta formation linked to Alzheimer's disease

New findings help identify impact of prenatal environment on early parental care on brain

Size of hippocampus may be linked to early dementia

Researchers find structural deficits in gray matter may be associated with daytime sleepiness

Early interference in entorhinal cortex may halt progression of Alzheimer's disease

Scientists identify events that causes AD progression

Study reveals a potential target for treating brain trauma

Molecular imaging technique pinpoints changes that take place in injured brain

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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