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Super-resolution imaging of the human coronavirus genome during infection

Using high-throughput confocal super-resolution microscopy, scientists visualize the genomic material of the human coronavirus HCoV-229E.

9 Feb 2022

Newborn antibodies following maternal COVID-19 vaccination persist for up to six months

A new study compares antibody levels in newborns born from mothers vaccinated against COVID-19 and to maternal infection with SARS-CoV-2.

9 Feb 2022

The serious risks COVID-19 may pose during pregnancy

Researchers report on the potential for serious maternal illness or death during or following a pregnancy complicated by COVID-19.

9 Feb 2022

How SARS-CoV-2 infection progresses throughout the respiratory system

Researchers discuss the progression of SARS-CoV-2 infection throughout the respiratory epithelium.

9 Feb 2022

Study explores inflammation of endothelial cells by exosomes from COVID-19 patients

In a new study, researchers revealed that the nucleotide-binding oligomerization domain-like receptors or NOD-like receptors family pyrin domain containing 3 (NLRP3) inflammasome is activated by the exosomes from plasma in COVID-19.

9 Feb 2022

Cocktail of two chemicals could help slow down age-related muscular decline

Researchers from Tokyo Metropolitan University have shown that a mixture of 5-aminolevulinic acid(5-ALA) hydrochloride and sodium ferrous citrate (SFC) helps slow down aging-related muscular decline in fruit flies, leading to a slower decline in locomotor activity and longer lifespans.

7 Feb 2022

Booster vaccines found to augment T-cell responses to SARS-CoV-2 Omicron

In a recent study published in the latest issue of the journal Cell, a team of researchers evaluated T-cell reactivity to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant's spike (S) and non-spike proteins.

6 Feb 2022

Researchers discover a new function of anti-HIV-1 antibodies

Teams at the Institut Pasteur, CNRS, Vaccine Research Institute (VRI) and Université de Paris have discovered a new function of anti-HIV-1 antibodies by applying cutting-edge microscopy techniques to in vitro viral cultures.

6 Feb 2022

Scientists elucidate the structure of central cellular inflammatory switch

Researchers at the Universities of Bonn and Regensburg have elucidated the structure of a central cellular inflammatory switch.

4 Feb 2022

Hp-XeMRI identifies impaired gas transfer in lungs of non-hospitalised breathless Long-COVID patients with normal CT scans

Researchers have been investigating the symptoms and effect on the lungs in those who suffered from hospitalization due to COVID-19 but fully recovered and non-hospitalized sufferers of long-COVID.

4 Feb 2022

Researchers develop influenza virus-like particle-based hybrid vaccine for both influenza and SARS-CoV-2 viruses

In a new study, a team of researchers developed a hybrid vaccine for SARS-CoV-2 and influenza viruses using influenza virus-like particles (VLP).

4 Feb 2022

Study shows positive outcomes in COVID-19 patients who underwent lung transplants

For many COVID-19 patients with irrecoverable lung damage, transplantation is the only option for survival. However, there is limited information about the long-term outcomes of these patients, including postoperative complications, hospital length of stay and survival.

3 Feb 2022

Study finds pediatric acute upper airway infection cases have increased during the Omicron variant surge

Researchers conducted a retrospective cohort study to determine if pediatric acute upper airway infection was more common during the surge of the Omicron strain of SARS-CoV-2 in the US.

3 Feb 2022

Researchers elucidate first 3D structure of regulator protein complex

Proteins are indispensable components in living organisms. They are not only "building material" for the body – they also make molecular communication between cells possible, they are needed for nerve impulses to occur, and they control chemical reactions.

2 Feb 2022

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

Researchers from China summarized the representative structures of SARS-CoV-2 proteins and discussed the development of novel therapeutic agents for targeting these proteins to treat and prevent COVID-19.

2 Feb 2022

Study confirms SARS-CoV-2 Omicron variant has a decreased ability to enter lung cells

A large multinational group of researchers has shown how the Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has gained exceptional immune evasion properties but also a much lower propensity to enter cells such as those in lung alveoli, resulting in its reduced pathogenicity. Their paper is currently released as an unedited version of the manuscript prior to publication in the journal Nature.

1 Feb 2022

SARS-CoV-2 entry at the cell surface facilitated by trypsin

Exogenous trypsin treatment boosts SARS-CoV-2 infection in Vero E6 cells and promotes viral multiplication in cultured cells.

1 Feb 2022

Neural stem cells plus HER2 inhibitor drug improve survival in mice with metastatic cancer

Neural stem cells (NSCs) engineered by Northwestern Medicine investigators used in combination with the HER2 inhibitor drug tucatinib improved survival in mice with HER2-positive breast cancer brain metastases, according to findings published in Proceedings of the National Academy of Sciences.

1 Feb 2022

Researchers visualize protein machinery of respiration for the first time

Oxygen and sugar are the basis of life for animals, plants, fungi and many bacteria. The metabolic process called respiration makes it possible to convert food into energy for the cells.

31 Jan 2022

Drugs derived from activated protein C may limit ischemia and reperfusion injury, study suggests

A University of South Florida Health preclinical study offers molecular insight into how activated protein C (APC) may improve aging patients' tolerance to reperfusion injury – a potentially adverse effect of treatment for ischemic heart disease.

31 Jan 2022

Membrane News and Research

Super-resolution imaging of the human coronavirus genome during infection

Newborn antibodies following maternal COVID-19 vaccination persist for up to six months

The serious risks COVID-19 may pose during pregnancy

How SARS-CoV-2 infection progresses throughout the respiratory system

Study explores inflammation of endothelial cells by exosomes from COVID-19 patients

Cocktail of two chemicals could help slow down age-related muscular decline

Booster vaccines found to augment T-cell responses to SARS-CoV-2 Omicron

Researchers discover a new function of anti-HIV-1 antibodies

Scientists elucidate the structure of central cellular inflammatory switch

Hp-XeMRI identifies impaired gas transfer in lungs of non-hospitalised breathless Long-COVID patients with normal CT scans

Researchers develop influenza virus-like particle-based hybrid vaccine for both influenza and SARS-CoV-2 viruses

Study shows positive outcomes in COVID-19 patients who underwent lung transplants

Study finds pediatric acute upper airway infection cases have increased during the Omicron variant surge

Researchers elucidate first 3D structure of regulator protein complex

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

Study confirms SARS-CoV-2 Omicron variant has a decreased ability to enter lung cells

SARS-CoV-2 entry at the cell surface facilitated by trypsin

Neural stem cells plus HER2 inhibitor drug improve survival in mice with metastatic cancer

Researchers visualize protein machinery of respiration for the first time

Drugs derived from activated protein C may limit ischemia and reperfusion injury, study suggests

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

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Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo