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Researchers reveal mechanism by which MAF protein increases metastasis risk in breast cancer patients

Breast cancer is the most common form of cancer among women, with more than 2 million new cases diagnosed each year. In cases where the tumour remains localised in the breast, survival rates are remarkably high, at around 90%.

9 Nov 2023

Tumor-immune interactions predict treatment responses in multiple myeloma

A multicenter study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine shows how interactions between tumor cells and immune components of the microenvironment can impact treatment responses and outcomes in patients newly diagnosed with multiple myeloma who undergo combination treatments that include targeted immunotherapy.

9 Nov 2023

COVID Moonshot Consortium makes major breakthrough in antiviral drug discovery

The work of the COVID Moonshot Consortium is being published in the prestigious journal Science on 10 November, revealing their discovery of a potent SARS-CoV-2 antiviral lead compound.

9 Nov 2023

Scientists discover kidney-friendly antifungal that evades resistance

In this investigation, researchers produced powerful antifungals of the polyene class without nephrotoxicity.

9 Nov 2023

Charting the future of IBD treatment: From immune modulators to microRNA therapies

In a recent study published in the journal eGastroenterology, researchers delved into the latest therapeutic strategies for managing inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. The paper discusses emerging treatments ranging from immune-modulating drugs and biologics to novel approaches like microRNA upregulators and stem cell therapies, highlighting the need for precision medicine in IBD care.

8 Nov 2023

New antifungal molecule shows promise in combatting fungal infections without toxicity

A new antifungal molecule, devised by tweaking the structure of prominent antifungal drug Amphotericin B, has the potential to harness the drug's power against fungal infections while doing away with its toxicity, researchers at the University of Illinois Urbana-Champaign and collaborators at the University of Wisconsin-Madison report in the journal Nature.

8 Nov 2023

New prodrug approach enhances drug delivery to brain cells

A new study from the University of Eastern Finland shows that the delivery of drugs into the brain, and especially into glial cells, can be enhanced with prodrugs that temporarily incorporate thyroxine or a thyroxine-like molecule.

8 Nov 2023

Blood tests can detect inflammatory bowel disease years before symptoms appear

Researchers at the Francis Crick Institute and Aalborg University in Copenhagen have shown that changes can be detected in blood tests up to eight years before a diagnosis of Crohn's disease and up to three years before a diagnosis of ulcerative colitis.

7 Nov 2023

How glucose restriction makes lung cancer cells more aggressive

One of the hallmarks of cancer cell development is its dependence on sugar, especially glucose, to grow and divide.

7 Nov 2023

Novel and emerging therapies offer new hope for patients with inflammatory bowel disease

Ulcerative colitis (UC) and Crohn's disease (CD) are chronic inflammatory bowel diseases (IBD) that affect the gastrointestinal tract.

7 Nov 2023

New drug shows promise in blocking pancreatic cancer spread

While the overall cancer death rate has been steadily declining in the U.S. since the 1990s, death rates due to pancreatic cancer are increasing.

7 Nov 2023

Stellaromics secures $25 million in series a funding to advance 3D spatial multi-omic profiling

Stellaromics today announced that the company has raised $25 million in a Series A financing round.

7 Nov 2023

UTHSC's drug candidate for advanced prostate cancer goes to first clinical trial

A drug candidate developed by researchers at the University of Tennessee Health Science Center for advanced metastatic castration-resistant prostate cancer is now in its first clinical trial.

6 Nov 2023

Scientists develop tissue adhesive gelatin hydrogels to speed up wound healing, prevent infections

Open wounds, whether caused by accidents or from medical procedures like surgery, require proper management to speed up healing and prevent infections.

6 Nov 2023

Synthetic melanin nanoparticles boost wound healing and tissue repair in skin

In a recent study published in npj Regenerative Medicine, researchers discuss the ability of melanin nanoparticles to support wound recovery in mice. The effects at histological and gene levels were explored and confirmed on biomimetic models and human skin explants.

5 Nov 2023

New pathway to combat cardiovascular disease identified

Research led by the University of Minnesota Medical School identified a new pathway to combat cardiovascular disease. The study was recently published in Nature Cardiovascular Research.

3 Nov 2023

Researchers pioneer a novel treatment for the most common autoimmune encephalitis

Researchers at DZNE and Charité - Universitätsmedizin Berlin have pioneered a novel treatment for the most common autoimmune encephalitis.

3 Nov 2023

Study reveals how formaldehyde alters gene expression through epigenetics

Epigenetics, the chemical mechanisms that controls the activity of genes, allows our cells, tissues and organs to adapt to the changing circumstances of the environment around us.

2 Nov 2023

Tufts researchers explore the science of aging

Anti-wrinkle creams, superfoods that keep you young, dietary supplements that promise improved memory, "immortal" cells that can renew themselves forever - in our stores and media, claims about aging abound.

2 Nov 2023

TUM start-up nominated for Science Breakthrough of the Year at Falling Walls summit

It all began with basic research: While conducting laboratory experiments, a team at the Technical University of Munich (TUM) came across an active agent against multidrug-resistant bacteria with a fundamental difference to antibiotics developed to date.

2 Nov 2023

Molecule News and Research

Researchers reveal mechanism by which MAF protein increases metastasis risk in breast cancer patients

Tumor-immune interactions predict treatment responses in multiple myeloma

COVID Moonshot Consortium makes major breakthrough in antiviral drug discovery

Scientists discover kidney-friendly antifungal that evades resistance

Charting the future of IBD treatment: From immune modulators to microRNA therapies

New antifungal molecule shows promise in combatting fungal infections without toxicity

New prodrug approach enhances drug delivery to brain cells

Blood tests can detect inflammatory bowel disease years before symptoms appear

How glucose restriction makes lung cancer cells more aggressive

Novel and emerging therapies offer new hope for patients with inflammatory bowel disease

New drug shows promise in blocking pancreatic cancer spread

Stellaromics secures $25 million in series a funding to advance 3D spatial multi-omic profiling

UTHSC's drug candidate for advanced prostate cancer goes to first clinical trial

Scientists develop tissue adhesive gelatin hydrogels to speed up wound healing, prevent infections

Synthetic melanin nanoparticles boost wound healing and tissue repair in skin

New pathway to combat cardiovascular disease identified

Researchers pioneer a novel treatment for the most common autoimmune encephalitis

Study reveals how formaldehyde alters gene expression through epigenetics

Tufts researchers explore the science of aging

TUM start-up nominated for Science Breakthrough of the Year at Falling Walls summit

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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