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RNA-based molecular subtypes can help predict response to chemotherapy in muscle-invasive bladder cancer

RNA-based molecular subtypes modestly improved predictions for pathologic downstaging in muscle-invasive bladder cancer.

15 Nov 2023

New diagnostic workflow improves detection of 5q-spinal muscular atrophy

5q-spinal muscular atrophy (5q-SMA) is one of the more common types of spinal muscular atrophy (SMA) affecting around one in ten thousand individuals worldwide.

15 Nov 2023

Bioengineered human heart muscle cells and micro-tissues take flight to space

Mount Sinai's Cardiovascular Research Institute is sending bioengineered human heart muscle cells and micro-tissues into space for the first time on NASA's 29th SpaceX commercial resupply services mission, which launched Thursday, November 9.

14 Nov 2023

Does narcissism drive our body image and dietary choices?

Study evaluates the relationship between narcissism and body image concerns, revealing how narcissistic traits influence desires for thinness and muscularity, and related dietary behaviors, with variations noted across genders.

13 Nov 2023

Study shows environment's pivotal role in healthy aging and disease prevention

Study explores new geroscience tools for studying the impact of environmental factors on aging, aiming to delay age-related diseases and disabilities. It highlights how non-genetic factors, like environmental toxins and socio-economic conditions, significantly influence aging and health outcomes.

13 Nov 2023

KAIST researchers develop an IV needle that irreversibly softens upon insertion

Intravenous (IV) injection is a method commonly used in patient's treatment worldwide as it induces rapid effects and allows treatment through continuous administration of medication by directly injecting drugs into the blood vessel.

13 Nov 2023

CRISPR-based gene-editing therapy could offer hope for people with inherited high LDL cholesterol

A single infusion of a CRISPR-based gene-editing therapy significantly reduced low-density lipoprotein cholesterol (LDL, the "bad cholesterol") in people who carry one gene for the inherited condition that results in very high LDL cholesterol levels and a high risk of heart attack at an early age, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

Changing environment can have long-term, significant effects on the brain

Changes in a person's environment can have long-term, significant effects on the brain, whether it's the inhalation of wildfire smoke or the experience of childhood trauma.

13 Nov 2023

SELECT trial: Semaglutide reduces cardiovascular events by 20% in overweight or obese patients without diabetes

Findings from a multi-center, international clinical trial reported by a Cleveland Clinic physician show that semaglutide reduced cardiovascular events by 20% in adults with overweight or obesity and established cardiovascular disease who do not have diabetes.

13 Nov 2023

UCI researchers discover gene critical for muscle repair

University of California, Irvine researchers have identified a gene expressed during regeneration that is critical for muscle repair.

12 Nov 2023

Study finds significant associations between sex work and muscle dysmorphia

Using data from over 900 participants in a large, diverse, and national sample of Canadian adolescents and young adults from the Canadian Study of Adolescent Health Behaviors, a new study published in the journal Sexual Health researchers found significant associations between sex work and muscle dysmorphia.

10 Nov 2023

One in six patients with coronary artery disease found to have non-ischemic or dual cardiomyopathy

Researchers from the University of Minnesota Medical School examining the cause of cardiomyopathy discovered one out of every six patients with coronary artery disease had non-ischemic or dual cardiomyopathy.

10 Nov 2023

Study shows rhesus macaques as an ideal animal model for studying pelvic organ prolapse

This study is led by Prof. Lan Zhu (Department of Obstetrics and Gynecology, Peking Union Medical College Hospital), Prof. Tao Tan (State Key Laboratory of Primate Biomedical Research, Kunming University of Science and Technology), and Prof. Weizhi Ji (State Key Laboratory of Primate Biomedical Research, Kunming University of Science and Technology).

10 Nov 2023

New insights into migraine etiology: the role of hepatocyte growth factor

The causal links between pro-inflammatory cytokine expression and migraine.

10 Nov 2023

New AI-powered growth chart tracks muscle mass in growing children

Leveraging artificial intelligence and the largest pediatric brain MRI dataset to date, researchers have now developed a growth chart for tracking muscle mass in growing children.

9 Nov 2023

New drug shows exciting promise for the treatment of ALS

In science, a simple but thorough observation can kick-start the most surprising findings. Researchers at the Hollings Cancer Center at the Medical University of South Carolina noticed that mice lacking a protein of interest in cancer research were showing visible signs of abnormal motor functions as they aged, including loss of coordination and strength.

8 Nov 2023