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COVID-19 reduces male fertility by affecting semen quality and hormone levels

Study reveals that SARS-CoV-2 significantly impairs male fertility by reducing semen quality and altering reproductive hormone levels, with partial recovery post-treatment.

11 Sep 2024

Women experience greater weight loss with tirzepatide compared to men

All doses of tirzepatide, a medication approved in the EU to treat type 2 diabetes and obesity, consistently reduced body weight in women and men, but women experienced greater weight loss, according to new post hoc research to be presented at this year's Annual Meeting of The European Association for the Study of Diabetes (EASD), Madrid (9-13 Sept).

11 Sep 2024

Telisotuzumab vedotin shows promising results in asian patients with c-Met overexpressing NSCLC

The c-Met-directed antibody-drug conjugate telisotuzumab vedotin demonstrated durable responses and an acceptable safety profile in patients of Asian race with c-Met protein-overexpressing, epidermal growth factor receptor (EGFR) wildtype (WT), locally advanced/metastatic nonsquamous non-small cell lung cancer (NSCLC), according to research presented today at the International Association for the Study of Lung Cancer's 2024 World Conference on Lung Cancer.

11 Sep 2024

Zongertinib shows promising efficacy in HER2 mutation-positive NSCLC

The HER2-specific tyrosine kinase inhibitor zongertinib was well tolerated and demonstrated promising efficacy in patients with HER2 mutation-positive non-small cell lung cancer, meeting the primary endpoint of the Beamion LUNG-1 Phase Ib Cohort 1 study, according to research presented today at the International Association for the Study of Lung Cancer 2024 World Conference on Lung Cancer.

11 Sep 2024

VitelloTag approach offers new solution for gene editing challenges in egg cells

A new approach for delivering miniature research tools into the interior of egg cells and embryos has been developed at the Marine Biological Laboratory (MBL), resolving a major bottleneck to using the gene-editing tool CRISPR-Cas9 in many research organisms.

11 Sep 2024

PDX engraftment predicts high recurrence and poor survival in triple-negative breast cancer

Researchers examine the association between patient-derived xenograft with recurrence and survival rates in triple negative breast cancer patients.

11 Sep 2024

TAAR1 gene: A new key to mental health

In the complex landscape of mental health research, a new peer-reviewed Viewpoint review sheds light on an underexplored genetic player: the trace amine-associated receptor 1 (TAAR1). Published in Genomic Psychiatry (ISSN: 2997-2388, Genomic Press, New York), this thought-provoking analysis suggests that mutations in the TAAR1 gene may be a crucial piece of the puzzle in understanding and treating neuropsychiatric disorders.

11 Sep 2024

Fibrous scars drive glioblastoma recurrence

A Ludwig Cancer Research study has discovered that recurrent tumors of the aggressive brain cancer glioblastoma multiforme (GBM) grow out of the fibrous scars of malignant predecessors destroyed by interventions such as radiotherapy, surgery, and immunotherapy.

11 Sep 2024

Obesity medication liraglutide safe and effective in children under 12, research finds

The obesity medication liraglutide is safe and effective in children aged 6 to <12 years, new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Madrid, Spain (9-13 September), and published simultaneously in the New England Journal of Medicine (NEJM), has found.

10 Sep 2024

Once-a-day oral weight loss drug shows promising results in reducing body weight

Individuals who received a once-a-day oral weight loss drug lost up to 13% of their body weight over three months, the annual meeting of the European Association for the Study of Diabetes (EASD) in Madrid, Spain (9-13 September) will hear.

10 Sep 2024

Girls exposed to endocrine-disrupting chemicals may be more likely to start puberty early

Girls exposed to certain endocrine-disrupting chemicals (EDCs) may be more likely to start puberty early, according to new research published in Endocrinology, the flagship basic science journal of the Endocrine Society.

10 Sep 2024

GLP-1 receptor agonists show promise in treating substance use disorders

A systematic review reveals that GLP-1 receptor agonists may help reduce certain substance use disorders, but findings are inconsistent due to study variability and patient differences.

9 Sep 2024

Research confirms safety of breastfeeding for breast cancer survivors with BRCA mutations

According to two international studies presented at the ESMO Congress 2024, women who breastfeed after receiving treatment for breast cancer, including those with a germline BRCA mutation (an inherited change in BRCA genes that significantly increases the risk of developing certain cancers, especially breast cancer), do not face an increased risk of recurrence or developing new breast cancers.

9 Sep 2024

Researchers uncover mechanism fueling prostate cancer

Researchers at the University of Michigan Health Rogel Cancer Center have uncovered a key reason why a typically normal protein goes awry and fuels cancer.

9 Sep 2024

Best ways to quit smoking: E-cigs, medications, and counseling proven effective in new Cochrane analysis

Recent Cochrane reviews highlight effective smoking cessation interventions, revealing gaps in research and the need for improved tobacco addiction strategies.

9 Sep 2024

Breakthrough technology detects cancer mutant genes with unprecedented sensitivity

Dr. Min-young Lee and Dr. Sung-gyu Park of the Advanced Bio and Healthcare Materials Research Division at KIMS have developed a technology that can detect cancer mutant genes in blood with the world's highest sensitivity of 0.000000001% based on plasmonic nanomaterials for optical signal amplification.

6 Sep 2024

Study reveals how sex hormones regulate immune system functions

Findings indicate that testosterone therapy in trans men alters immune system responses, suggesting implications for disease susceptibility and treatment.

6 Sep 2024

Early cholesterol spikes fuel atherosclerosis by altering macrophages

Early intermittent hyperlipidemia significantly accelerates atherosclerosis by disrupting macrophage function, highlighting the need for early cholesterol management.

6 Sep 2024

New RNA therapy offers hope for mental health

Scientists at Cognigenics have made a significant advance in the field of neuroscience and mental health treatment. Their groundbreaking research, published in Genomic Psychiatry, demonstrates that a new RNA-based therapy called COG-201 can enhance memory and reduce anxiety in animal models.

6 Sep 2024

Aging immune system fuels cancer growth

A novel study by researchers at the Icahn School of Medicine at Mount Sinai addresses a critical yet under-explored question in cancer research: Why is aging the biggest risk factor for cancer? The study reveals how an aging immune system spurs tumor growth, offering new insights into cancer prevention and treatment, especially for older adults.

6 Sep 2024

Receptor News and Research

COVID-19 reduces male fertility by affecting semen quality and hormone levels

Women experience greater weight loss with tirzepatide compared to men

Telisotuzumab vedotin shows promising results in asian patients with c-Met overexpressing NSCLC

Zongertinib shows promising efficacy in HER2 mutation-positive NSCLC

VitelloTag approach offers new solution for gene editing challenges in egg cells

PDX engraftment predicts high recurrence and poor survival in triple-negative breast cancer

TAAR1 gene: A new key to mental health

Fibrous scars drive glioblastoma recurrence

Obesity medication liraglutide safe and effective in children under 12, research finds

Once-a-day oral weight loss drug shows promising results in reducing body weight

Girls exposed to endocrine-disrupting chemicals may be more likely to start puberty early

GLP-1 receptor agonists show promise in treating substance use disorders

Research confirms safety of breastfeeding for breast cancer survivors with BRCA mutations

Researchers uncover mechanism fueling prostate cancer

Best ways to quit smoking: E-cigs, medications, and counseling proven effective in new Cochrane analysis

Breakthrough technology detects cancer mutant genes with unprecedented sensitivity

Study reveals how sex hormones regulate immune system functions

Early cholesterol spikes fuel atherosclerosis by altering macrophages

New RNA therapy offers hope for mental health

Aging immune system fuels cancer growth

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