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Researchers describe structure of Alzheimer fibrils at atomic resolution

Elongated fibres (fibrils) of the beta-amyloid protein form the typical senile plaque present in the brains of patients with Alzheimer's disease.

5 Aug 2016

Lipopeptides released by staphylococci play key role in triggering septicemia

Septicemia or blood poisoning caused by Staphylococcus aureus leads to thousands of deaths each year in Germany alone. Just how the infection begins - and can lead to multiple organ failure - was little understood until now.

4 Aug 2016

Researchers develop new hybrid method to study HIV protein involved in disease progression

More than 36 million people worldwide, including 1.2 million in the U.S., are living with an HIV infection. Today's anti-retroviral cocktails block how HIV replicates, matures and gets into uninfected cells, but they can't eradicate the virus.

3 Aug 2016

Study shows diabetes drug ineffective in improving condition of patients with advanced heart failure

In an attempt to correct defects in the energy generation that contribute to poor pump function among heart failure patients, researchers examined whether the diabetes drug liraglutide, could improve the condition of patients with advanced heart failure.

2 Aug 2016

Iron-containing catalysts can alter amino acids to help develop new drug candidates

For medicinal chemists, making tweaks to peptide structures is key to developing new drug candidates. Now, researchers have demonstrated that two iron-containing small-molecule catalysts can help turn certain types of amino acids -- the building blocks of peptides and proteins -- into an array of potential new forms, even when part of a larger peptide, while preserving a crucial aspect of their chemistry: chirality, or "handedness."

2 Aug 2016

Ortho Clinical Diagnostics to showcase seven posters of vital tests, six products at AACC meeting

Ortho Clinical Diagnostics today announced it will present seven scientific posters on its assays and display six products at its booth at the 2016 American Association for Clinical Chemistry annual meeting.

30 Jul 2016

FDA approves new injection to improve blood sugar levels in adults with type 2 diabetes

The U.S. Food and Drug Administration approved Adlyxin (lixisenatide), a once-daily injection to improve glycemic control (blood sugar levels), along with diet and exercise, in adults with type 2 diabetes.

28 Jul 2016

UNMC researcher aims to find workable solution for tackling antibiotic resistance

Sam Sanderson, Ph.D., a research associate professor in the UNMC College of Pharmacy, recently secured an R01 grant from the National Institutes of Health to find a workable solution to the problem of antibiotic resistance.

28 Jul 2016

Levels of peptide hormone adropin linked to carbohydrate intake

In research featured in the August edition of Obesity, Saint Louis University investigator Andrew Butler, Ph.D., and his team report that levels of the peptide hormone adropin vary based on carbohydrate consumption and appear to be linked to lipid metabolism.

27 Jul 2016

Researchers find potential way for delivering gene therapy to treat eye diseases

Eye diseases such as diabetic retinopathy and age-related macular degeneration are among the leading causes of irreversible vision loss and blindness worldwide. Currently, gene therapy can be administered to treat these conditions -- but this requires an injection.

27 Jul 2016

Researchers identify new mechanisms capable of suppressing propagation of HCV

Researchers at Osaka University, Japan uncovered the mechanisms that suppress the propagation of the hepatitis C virus (HCV) with the potential of improving pathological liver conditions.

27 Jul 2016

Duke to lead early-stage clinical trials for promising new neurological therapies

Duke University could receive up to $19 million to lead early-stage clinical trials for new drugs to treat neurological conditions such as Alzheimer's disease and neuropathy.

22 Jul 2016

Long-term antibiotic treatment slows progression of Alzheimer's disease through changes in gut bacteria

Long-term treatment with broad spectrum antibiotics decreased levels of amyloid plaques, a hallmark of Alzheimer's disease, and activated inflammatory microglial cells in the brains of mice in a new study by neuroscientists from the University of Chicago.

21 Jul 2016

Researchers design inhibitory peptide to unleash defence mechanisms against fungal pathogens

For most people, a simple case of thrush or athlete's foot can be quickly and easily treated using over-the-counter anti-fungal creams and pills.

19 Jul 2016

Novel biomarkers may offer solution for detecting autologous blood transfusion in athletes

Increasing oxygen delivery to muscles can help athletes perform better and give them the edge needed to win elite competitions. One of the best ways to increase oxygen supply is through blood manipulation, undergoing a blood transfusion that provides extra red blood cells and boosts oxygen levels.

19 Jul 2016

New type of HIV drug works in unusual way

A new type of HIV drug currently being tested works in an unusual way, scientists in the Molecular Medicine Partnership Unit, a collaboration between EMBL and Heidelberg University Hospital, have found.

17 Jul 2016

Researchers discover strong genetic risk factor for IgA nephropathy

An international research collaboration has discovered a strong genetic risk factor for IgA nephropathy (IgAN) - the most common inflammatory kidney disease worldwide - and related renal dysfunction.

14 Jul 2016

Single dose of new molecule could protect the brain from cognitive impairments after mTBI

A new molecule could protect the brain from cognitive impairments after a mild traumatic brain injury, according to Hebrew University of Jerusalem scientists.

11 Jul 2016

AMPK protein activated during fasting regulates hunger neurons in the brain

Neurons in the brain that control hunger are regulated by AMPK, a protein activated during fasting, report researchers from Tufts University School of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School in Neuron on July 6, 2016.

6 Jul 2016

Anaemia in heart failure may impact prognosis

Anaemia is common in patients with heart failure, regardless of the underlying phenotype, and is often associated with iron deficiency, UK researchers report.

6 Jul 2016

Peptides News and Research

Researchers describe structure of Alzheimer fibrils at atomic resolution

Lipopeptides released by staphylococci play key role in triggering septicemia

Researchers develop new hybrid method to study HIV protein involved in disease progression

Study shows diabetes drug ineffective in improving condition of patients with advanced heart failure

Iron-containing catalysts can alter amino acids to help develop new drug candidates

Ortho Clinical Diagnostics to showcase seven posters of vital tests, six products at AACC meeting

FDA approves new injection to improve blood sugar levels in adults with type 2 diabetes

UNMC researcher aims to find workable solution for tackling antibiotic resistance

Levels of peptide hormone adropin linked to carbohydrate intake

Researchers find potential way for delivering gene therapy to treat eye diseases

Researchers identify new mechanisms capable of suppressing propagation of HCV

Duke to lead early-stage clinical trials for promising new neurological therapies

Long-term antibiotic treatment slows progression of Alzheimer's disease through changes in gut bacteria

Researchers design inhibitory peptide to unleash defence mechanisms against fungal pathogens

Novel biomarkers may offer solution for detecting autologous blood transfusion in athletes

New type of HIV drug works in unusual way

Researchers discover strong genetic risk factor for IgA nephropathy

Single dose of new molecule could protect the brain from cognitive impairments after mTBI

AMPK protein activated during fasting regulates hunger neurons in the brain

Anaemia in heart failure may impact prognosis

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