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Specific immune suppression leads to severe COVID-19 disease

A new study published online on the preprint server medRxiv in May 2020 reports that specific changes in the way the human immune system responds to COVID-19 determine whether the individual develops moderate or severe illness.

2 Jun 2020

How comorbidities affect SARS-CoV-2 viral entry

Almost from the start of the current COVID-19 pandemic, it has become clear that individuals suffering from other medical conditions like diabetes, cardiovascular disease, and lung disease are far more likely to contract the infection and to have a poorer outcome.

28 May 2020

Ferritin heavy chain protein shows promise as a potential SARS-CoV-2 vaccine or antiviral

A new study published on the online preprint server bioRxiv in May 2020 reports the construction and testing of a new ferritin-based antigen-bearing protein that has biological activity towards the ACE2 receptor. This could indicate its potential for development as a vaccine or antiviral.

28 May 2020

Scientists create adenovirus that kills cancer cells

An adenovirus is now better able to target and kill cancer cells due to the addition of an RNA stabilizing element.

28 May 2020

ACE2 receptors in the kidney not linked to high BP or RAS blockers

Even as the COVID-19 pandemic continues to smolder and flare up in various parts of the world, researchers are still trying to make sense of the virus, its routes of spread, its target tissues, and the immune responses it induces. One crucial piece of knowledge is that the primary viral receptor is a human enzyme called angiotensin-converting enzyme 2 (ACE2).

27 May 2020

No-deductible preventive drugs can reduce out-of-pocket costs for diabetic patients

For patients with diabetes - especially those with lower incomes - preventive drug lists (PDLs) of essential medications available with no deductible can reduce out-of-pocket costs while increasing use of important treatments, reports a study in a June supplement to Medical Care.

27 May 2020

Capillary leakage important in COVID-19 respiratory distress

Now, a new study published on the preprint server medRxiv reports the pivotal role played by protein leakage through lung capillaries and promotes the use of serum albumin as a biomarker of disease progression and severity.

24 May 2020

Scientists create a detailed map of how carcinogens trigger breast cancer development

In the most comprehensive review to date of how breast cancer develops, scientists have created a detailed map that describes the many ways in which environmental chemicals can trigger the disease.

21 May 2020

Scientists use new model to develop cancer stem cells

Liver cancer is one of the deadliest cancers. It is insidious and does not present symptoms until it has progressed considerably, at which point, treatment options are limited and chances of survival are low. The most common type of liver cancer is hepatocellular carcinoma (HCC).

21 May 2020

Study could help identify more targeted treatments for ovarian cancer

The rogue cellular engine that drives a majority of ovarian cancers remains frustratingly difficult to disable. A new study comparing cancerous tissue with normal fallopian tube samples advances important insights about this machinery and confirms biological hallmarks of survival.

20 May 2020

Study shows how cancer protein changes may accelerate tumorigenesis and metastasis

Understanding the genetic mutations and protein changes that take place in the progression of cancer is key to its treatment. Mutations in the gene TP53 and concomitant mutant p53 proteins in cancer cells have become notorious over the course of multiple studies of several different types of cancers.

18 May 2020

Smoking increases ACE2 protein in the lungs which may promote COVID-19 infection

Previous data from COVID-19 patients suggests that cigarette smokers are more likely to have health complications.

18 May 2020

Well-known cancer drugs may prevent SARS-CoV-2 viral replication say researchers

Researchers in Frankfurt, Germany, have described cell signaling events that occur when severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells and have identified pathways that are essential for the virus to replicate.

17 May 2020

South Africa obtains first laboratory isolate of SARS-CoV-2

While much of the scientific and medical community rushes to develop therapeutic agents for COVID-19 based on clinical data, getting a better understanding of the brand-new virus remains crucial.

11 May 2020

COVID-19 could accelerate activation of dormant tuberculosis (TB)

The ongoing COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has thrown much of the world into disarray, with over 4 million people reported infected and well over 282,000 deaths. A new study published on the preprint server bioRxiv in May 2020 suggests that the long-term impact of the virus could include activation of dormant bacterial infections like tuberculosis (TB).

10 May 2020

UCD researcher awarded €500,000 SFI Future Innovator Prize for innovative imaging solution

Ireland's Minister for Business, Enterprise, and Innovation, Heather Humphreys, TD, has today announced that a special Science Foundation Ireland Future Innovator Prize of €500,000 has been granted to University College Dublin researcher, Professor Dominic Zerulla.

9 May 2020

Study: Genes may play a far more complex role in oocyte maturation than previously assumed

Over the last six years a group of Estonian geneticists led by Associate Professor Agne Velthut-Meikas and a PhD student Ilmatar Rooda from TalTech Department of Chemistry and Biotechnology have studied genes previously associated primarily with female hormone synthesis and ovarian follicle development.

7 May 2020

Interleukin-12 electroporation led to clinical responses in patients with advanced melanoma

Combining intratumoral electroporation of interleukin-12 (IL-12) DNA (tavokinogene telseplasmid, or TAVO) with the immune checkpoint inhibitor pembrolizumab (Keytruda) led to clinical responses in patients with immunologically quiescent advanced melanoma, according to results from a phase II trial.

6 May 2020

Sartorius launches the new Incucyte SX5® for live-cell analysis, offering new possibilities for live-cell analysis experiments

Sartorius, a leading international supplier for the biopharmaceutical industry, today launched the new Incucyte SX5 Live-Cell Analysis System, the latest in the company’s line of live-cell analysis products.

From Sartorius 5 May 2020

AM and 3D printing communities rally together to fight against COVID-19

The rapid proliferation of COVID-19 has been putting great strain on healthcare systems across the world, with demand for critical medical equipment and supplies mounting.

30 Apr 2020

Proliferation News and Research

Specific immune suppression leads to severe COVID-19 disease

How comorbidities affect SARS-CoV-2 viral entry

Ferritin heavy chain protein shows promise as a potential SARS-CoV-2 vaccine or antiviral

Scientists create adenovirus that kills cancer cells

ACE2 receptors in the kidney not linked to high BP or RAS blockers

No-deductible preventive drugs can reduce out-of-pocket costs for diabetic patients

Capillary leakage important in COVID-19 respiratory distress

Scientists create a detailed map of how carcinogens trigger breast cancer development

Scientists use new model to develop cancer stem cells

Study could help identify more targeted treatments for ovarian cancer

Study shows how cancer protein changes may accelerate tumorigenesis and metastasis

Smoking increases ACE2 protein in the lungs which may promote COVID-19 infection

Well-known cancer drugs may prevent SARS-CoV-2 viral replication say researchers

South Africa obtains first laboratory isolate of SARS-CoV-2

COVID-19 could accelerate activation of dormant tuberculosis (TB)

UCD researcher awarded €500,000 SFI Future Innovator Prize for innovative imaging solution

Study: Genes may play a far more complex role in oocyte maturation than previously assumed

Interleukin-12 electroporation led to clinical responses in patients with advanced melanoma

Sartorius launches the new Incucyte SX5® for live-cell analysis, offering new possibilities for live-cell analysis experiments

AM and 3D printing communities rally together to fight against COVID-19

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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