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People with accelerated biological age at increased risk of COVID-19 symptom severity and mortality

Now, a new study published on the preprint server medRxiv in July 2020 discusses the explanation in terms of the biological aging markers in patients with severe disease, rather than the chronological age.

13 Jul 2020

NUS teams develop three nasopharyngeal swab designs for COVID-19 testing

Since the outbreak of COVID-19, there has been a global surge in demand for nasopharyngeal (NP) swabs, a key element in testing for SARS-CoV-2. Singapore is no exception. Commercially available NP swabs used in COVID-19 test kits are often out of stock due to supply chain disruptions.

13 Jul 2020

Research shows how SARS-CoV-2 alters translation

Now, a new study published on the preprint server bioRxiv in July 2020 shows that the 5’ end of the RNA molecule is capable of inhibiting the binding of mRNA to the ribosomal 40S subunit, thus preventing translation.

9 Jul 2020

Researchers map RNA structure throughout SARS-CoV-2 genome

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which is currently at the heart of a pandemic that has cost the world more than 550,000 lives, 12 million infections, and uncounted years of productivity, is an RNA virus with the largest genome among all such viruses. This 30 kb size virus has caused many difficulties for scientists in search of a vaccine.

9 Jul 2020

Columbia behavioral scientist uses data science to confront healthcare inequality

Kai Ruggeri's research has one overriding objective: to improve the well-being of populations by confronting inequality.

8 Jul 2020

World's first clinical trial of immune-boosting strategy to protect cancer patients from COVID-19

In the race to find new ways to prevent and treat COVID-19, Canadian researchers have launched an innovative clinical trial focussed on strengthening the immune system for one of the most vulnerable populations - cancer patients.

8 Jul 2020

$5 million gift aims to propel Lyme disease research and education

To the Fairbairns, the symptoms--debilitating fatigue, joint pain, cognitive problems--were as worrisome as they were mystifying. All four members of the family had them.

6 Jul 2020

National Psoriasis Foundation announces $3.28 million in research grants and fellowships

The National Psoriasis Foundation, NPF, is proud to announce the awarding of $3.28 million in research grants and fellowships in 2020.

6 Jul 2020

Structure of the full SARS-CoV-2 RNA genome in infected cells

The current COVID-19 pandemic caused by a single-stranded RNA virus, thought to have jumped across species barriers to infect humans, has spread rapidly across the globe infecting over 10 million individuals. The virus, now known as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is the causative agent of COVID-19 disease. COVID-19 disease is a respiratory illness where symptoms can range from very mild to severe and include fever, coughing, a sore throat, and shortness of breath.

2 Jul 2020

Phosphorylation of SARS-CoV-2 N protein affects its function

Now, a new study by researchers at the University of California San Francisco and published on the preprint server bioRxiv* in June 2020 shows the effect of phosphorylation on the state and function of the N protein.

1 Jul 2020

Scientists discover osmotic stress as stimulator of cellular waste disposal

Cellular waste disposal, where autophagy and lysosomes interact, performs elementary functions, such as degrading damaged protein molecules, which impair cellular function, and reintroducing the resulting building blocks such as amino acids into the metabolic system.

29 Jun 2020

Enhanced photoacoustic imaging improves cancer staging

Prof. TIAN Chao's group from the Department of Precision Machinery and Instrumentation, University of Science and Technology of China of the Chinese Academy of Sciences has made progress on the photoacoustic imaging for medical science.

29 Jun 2020

Brazilian startup to develop a low-cost high-performance COVID-19 diagnostic test

Researchers at Biolinker, a biotech startup based in São Paulo, Brazil, are developing a low-cost high-performance COVID-19 diagnostic test using only locally sourced inputs.

26 Jun 2020

UK announces research partnership with Atomwise to explore potential COVID-19 therapies

The University of Kentucky announced a research collaboration with Atomwise, an industry leader in using artificial intelligence (AI) for small molecule discovery, to explore potential COVID-19 therapies

23 Jun 2020

Patient genetics associated with wound microbiome composition and healing

In a first-of-its-kind study, researchers have determined that genetics may play a role in how wounds heal.

22 Jun 2020

C-Path's Transplant Therapeutics Consortium receives positive FDA response for its Letter of Intent

Critical Path Institute announced today that its Transplant Therapeutics Consortium has received a positive response to its Letter of Intent from the U.S. Food and Drug Administration detailing the decision to accept the Composite Biomarker Panel (iBox Scoring System) into the Center for Drug Evaluation and Research (CDER) Biomarker Qualification Program.

17 Jun 2020

FSK-ML format can quickly predict disease risks from microbial pathogens in food

The 'Food Safety Knowledge Markup Language (FSK-ML)' format allows to uniformly document mathematical models and model-based simulation results, and make these available to other researchers for computer-based forecasts or further optimization of models.

17 Jun 2020

Trump’s take on COVID testing misses public health realities

President Donald Trump sought to downplay the numbers associated with COVID-19 in the United States — which have passed 2 million confirmed cases and are nearing 120,000 lives lost — by arguing that the soaring national count was simply the result of superior testing.

17 Jun 2020

Mapping RNA sequences of therapeutic value in the SARS-CoV-2 genome

Now, in new research published on the preprint server bioRxiv European scientists have performed RNA structure probing to obtain a single-base resolution secondary structure map of the full SARS-CoV-2 coronavirus genome.

17 Jun 2020

Researchers receive federal funding to rapidly repurpose FDA-approved drugs for COVID-19

Researchers at the University of Maryland School of Medicine will be partnering on an agreement funded by the federal government's Defense Advanced Research Projects Agency (DARPA) to rapidly test hundreds of drugs, approved and marketed for other conditions, to see whether any can be repurposed to prevent or treat COVID-19.

16 Jun 2020

Translation News and Research

People with accelerated biological age at increased risk of COVID-19 symptom severity and mortality

NUS teams develop three nasopharyngeal swab designs for COVID-19 testing

Research shows how SARS-CoV-2 alters translation

Researchers map RNA structure throughout SARS-CoV-2 genome

Columbia behavioral scientist uses data science to confront healthcare inequality

World's first clinical trial of immune-boosting strategy to protect cancer patients from COVID-19

$5 million gift aims to propel Lyme disease research and education

National Psoriasis Foundation announces $3.28 million in research grants and fellowships

Structure of the full SARS-CoV-2 RNA genome in infected cells

Phosphorylation of SARS-CoV-2 N protein affects its function

Scientists discover osmotic stress as stimulator of cellular waste disposal

Enhanced photoacoustic imaging improves cancer staging

Brazilian startup to develop a low-cost high-performance COVID-19 diagnostic test

UK announces research partnership with Atomwise to explore potential COVID-19 therapies

Patient genetics associated with wound microbiome composition and healing

C-Path's Transplant Therapeutics Consortium receives positive FDA response for its Letter of Intent

FSK-ML format can quickly predict disease risks from microbial pathogens in food

Trump’s take on COVID testing misses public health realities

Mapping RNA sequences of therapeutic value in the SARS-CoV-2 genome

Researchers receive federal funding to rapidly repurpose FDA-approved drugs for COVID-19

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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