Central Nervous System News and Research

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New approaches to prevent or treat antipsychotic-induced supersensitivity psychosis

In the current issue of Psychotherapy and Psychosomatic, professor Guy Chouinard, one of the most important psychopharmacologists, provides a synthesis of the data that are concerned with neglected side effects of commonly used psychotropic drugs.

8 Sep 2017

Scientists directly convert skin cells from healthy adults into motor neurons

Scientists working to develop new treatments for neurodegenerative diseases have been stymied by the inability to grow human motor neurons in the lab. Motor neurons drive muscle contractions, and their damage underlies devastating diseases such as amyotrophic lateral sclerosis and spinal muscular atrophy, both of which ultimately lead to paralysis and early death.

7 Sep 2017

Study identifies genetic alterations with potential to promote aggressiveness of astrocytomas

Among the various types of cancerous brain tumors, 70% are astrocytomas. Fatal in as many as 90% of cases, astrocytomas originate in the largest and most numerous cells in the central nervous system, called astrocytes because of their star shape.

6 Sep 2017

Testing Service Members for Heat Related Illnesses Before Combat

It is common to think that combat deployment is the most dangerous part of being a warfighter, and in many ways this is correct. However, warfighters need to do many things before they are cleared to deploy to combat zones. Most cases of exertional heat illness (EHI) reported in the U.S. military occur during non-combat activities, such as training regimens, ruck marches, and operational exercises.

From Physitemp Instruments LLC 6 Sep 2017

Biodegradable nanoparticle injected after spinal cord injury limits damage

After a spinal cord injury, a significant amount of secondary nerve damage is caused by inflammation and internal scarring that inhibits the ability of the nervous system to repair itself.

5 Sep 2017

Genetics of circadian rhythms found to have effect on migraine

People with a specific variation in the CLOCK gene have more migraines under financial stress. This work, the first time that the genetics of circadian rhythms has been shown to have an effect on migraine, is presented at the ECNP conference in Paris.

4 Sep 2017

Researchers reveal reason for reduced release of satiety hormones in obese people

Individuals with severe overweight have an inhibited sense of satiation - they release fewer satiety hormones than people of normal weight.

29 Aug 2017

LSU Health New Orleans receives $10 million grant to support research on virus-induced cancers

The National Institute of General Medical Sciences has awarded LSU Health New Orleans a $10 million grant over five years to support new basic research studies advancing the development new diagnostic and therapeutic approaches for virus-induced cancers.

26 Aug 2017

Astex celebrates as breast cancer drug gets European marketing approval

Astex Pharmaceuticals, a pharmaceutical company dedicated to the discovery and development of novel small molecule therapeutics for oncology and diseases of the central nervous system, announced today that its long-standing pharmaceutical collaborator, Novartis, has received marketing approval in Europe for Kisqali (ribociclib) plus an aromatase inhibitor as a first-line treatment in post-menopausal women with hormone receptor positive, human epidermal growth factor receptor-2 negative (HR+/HER2-) locally advanced or metastatic breast cancer.

26 Aug 2017

Study identifies promising drug candidate for treating demyelinating diseases

Brain functions are maintained by the neural network. Neural network is formed by the connection between the neurite, and this connection is supported by the wrapping of myelin.

26 Aug 2017

Neuronal firing patterns influence proliferation, differentiation of oligodendrocyte precursors

Through their pattern of firing, neurons influence the behavior of the cells that upon maturation will provide insulation of neuronal axons, according to a new study publishing 22 August in the open access journal PLOS Biology by Balint Nagy, Maria Kukley and colleagues at the University of Tübingen, Germany.

23 Aug 2017

Researchers uncover evidence linking mental health disorders and disturbances to gut microbiome

Better understanding the gastrointestinal microbiome may help psychiatrists treat mental health disorders such as depression, highlights a review in Frontiers in Psychiatry.

23 Aug 2017

Oropouche virus could cause serious public health problem in Brazil, researcher warns

After the Zika epidemic, which began in 2015, and the outbreak of yellow fever early in 2017, Brazil runs a serious risk of being afflicted by Oropouche, another virus that is widely distributed throughout South and Central America and the Caribbean.

22 Aug 2017

Noninvasive retinal imaging may detect pathological hallmarks of Alzheimer's disease

A study led by researchers at Cedars-Sinai and NeuroVision Imaging LLC provides the scientific basis for using noninvasive eye imaging to detect the pathological hallmarks of Alzheimer's.

22 Aug 2017

Routine dental checkups offer opportunity to observe changes in patient’s health

Dentists and hygienists see more than just teeth. They can see early signs of certain diseases - often before patients know they have them.

22 Aug 2017

Bionic vision restoration: could future technologies restore sight?

The brain is very plastic, which means that the brain is able to adapt to new signals. In the case of bionic vision restoration, the photoreceptors have died, the brain is not receiving anything biologically, and you are going to then send something which is artificial, prosthetic, and has been created outside the body.

21 Aug 2017

Chronic stress triggers fatal organ failure via new neural pathway

New research reveals the mechanisms behind the effects of chronic stress and tiny inflammations in the brain on fatal gut failure.

21 Aug 2017

Scientists reveal differences between human and murine microglia used in degenerative disease research

The results of a new research showed that many of the genes that are expressed by microglia are different between humans and mice, which are frequently used as animal models in research on Alzheimer's disease and other neurodegenerative disorders.

18 Aug 2017

Drug blocked by regulators found to improve quality of life for MS patients

A drug that is blocked by the EU regulatory system has now been found to improve the quality of life of people with multiple sclerosis (MS), according to a study by Queen Mary University of London.

18 Aug 2017

Study shows feasibility of noninvasive retinal imaging for screening people at risk of AD

Alzheimer's disease (AD) represents the leading cause of dementia worldwide. Currently, challenges in making an early and definitive diagnosis of AD limit opportunities to intervene with disease-modifying therapies before substantial neurodegeneration occurs.

17 Aug 2017

Central Nervous System News and Research

New approaches to prevent or treat antipsychotic-induced supersensitivity psychosis

Scientists directly convert skin cells from healthy adults into motor neurons

Study identifies genetic alterations with potential to promote aggressiveness of astrocytomas

Testing Service Members for Heat Related Illnesses Before Combat

Biodegradable nanoparticle injected after spinal cord injury limits damage

Genetics of circadian rhythms found to have effect on migraine

Researchers reveal reason for reduced release of satiety hormones in obese people

LSU Health New Orleans receives $10 million grant to support research on virus-induced cancers

Astex celebrates as breast cancer drug gets European marketing approval

Study identifies promising drug candidate for treating demyelinating diseases

Neuronal firing patterns influence proliferation, differentiation of oligodendrocyte precursors

Researchers uncover evidence linking mental health disorders and disturbances to gut microbiome

Oropouche virus could cause serious public health problem in Brazil, researcher warns

Noninvasive retinal imaging may detect pathological hallmarks of Alzheimer's disease

Routine dental checkups offer opportunity to observe changes in patient’s health

Bionic vision restoration: could future technologies restore sight?

Chronic stress triggers fatal organ failure via new neural pathway

Scientists reveal differences between human and murine microglia used in degenerative disease research

Drug blocked by regulators found to improve quality of life for MS patients

Study shows feasibility of noninvasive retinal imaging for screening people at risk of AD

Event guide: The 7th CNS Drug Delivery Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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