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P323L mutations in SARS-CoV-2 are highly predictive of the emergence of new variants

In a new study, findings suggest that in some cases, tracking the distribution and frequency of SARS-CoV-2 minor variant genomes at a population level would help in predicting the emergence of a new dominant viral genome sequence.

30 Dec 2021

Rapid antigen tests show lower sensitivity for Omicron than for earlier SARS-CoV-2 variants

Researchers carried out an analytical susceptibility test with cultured SARS-CoV-2 Omicron variant in seven antigen-detecting rapid diagnostic (Ag-RDTs).

29 Dec 2021

Omicron analysis shows no clear evidence for increased virulence or lethality

Researchers conducted a genomic sequencing and epidemiological correlation analysis of the SARS-CoV-2 Omicron variant.

29 Dec 2021

MRNA boosters shown to increase protection against SARS-CoV-2 Omicron

Researchers evaluate vaccine effectiveness against SARS-CoV-2 Omicron and Delta variants.

29 Dec 2021

Study suggests saliva swabs may be more suitable for omicron detection

New study findings reveal that saliva samples are more useful than mid-turbinate samples for the accurate detection of omicron infection.

29 Dec 2021

New strategy to create a cheap and rapid COVID-19 test based on isothermal amplification

Russian researchers have developed a strategy to create a cheap and rapid COVID-19 test based on isothermal amplification. According to their publication in Applied Biochemistry and Microbiology, use of this strategy will make it possible to create universal test systems for any of the COVID-19 variants.

29 Dec 2021

New report on 1.23 million breakthrough symptomatic SARS-CoV-2 infections by vaccine

A new research letter evaluates whether the estimated vaccine effectiveness changes against infection over time.

28 Dec 2021

Allele-specific RT-qPCR assay to identify SARS-CoV-2 Omicron variant in wastewater

Researchers develop a new allele-specific RT-qPCR to detect the SARS-CoV-2 Omicron variant in wastewater.

23 Dec 2021

Coinfection of SARS-CoV-2 and human rhinovirus associated with more severe health outcomes

Researchers discuss the incidence and effect of coinfections with SARS-CoV-2 and human rhinovirus.

23 Dec 2021

Assessing the clinical severity of the SARS-CoV-2 Omicron variant

A recent preprint examines the proportion of Omicron infection and the risk of severe disease with this variant of SARS-CoV-2.

23 Dec 2021

More breakthrough infections but less severe COVID-19 with Omicron

In a recent study posted to the bioRxiv* pre-print server, an international team of researchers reported the occurrence of coronavirus disease 2019 (COVID-19) breakthrough infections (BTIs) among health care workers (HCWs) participating in a phase III vaccine trial in Sisonke, South Africa.

22 Dec 2021

Study confirms coronavirus RNA synthesis occurs inside membrane-bound compartments

Researchers have experimentally proved that virus-related double-stranded RNA (dsRNA) and the sites of viral RNA synthesis are associated with one another.

22 Dec 2021

Role of novel SARS-CoV-2-derived svRNAs and the involvement of tRF in COVID-19

A new study revealed new long sv-COV-2 using T4 PNK pretreatment and qRT-PCR and also identified piRNAs and tRFs as the most abundant sncRNAs in COVID-19 positive samples.

22 Dec 2021

Sensor based on quantum effects may offer faster and accurate detection of SARS-CoV-2 virus

A novel approach to testing for the presence of the virus that causes Covid-19 may lead to tests that are faster, less expensive, and potentially less prone to erroneous results than existing detection methods. Though the work, based on quantum effects, is still theoretical, these detectors could potentially be adapted to detect virtually any virus, the researchers say.

21 Dec 2021

Polymerase News and Research

P323L mutations in SARS-CoV-2 are highly predictive of the emergence of new variants

Rapid antigen tests show lower sensitivity for Omicron than for earlier SARS-CoV-2 variants

Omicron analysis shows no clear evidence for increased virulence or lethality

MRNA boosters shown to increase protection against SARS-CoV-2 Omicron

Study suggests saliva swabs may be more suitable for omicron detection

New strategy to create a cheap and rapid COVID-19 test based on isothermal amplification

New report on 1.23 million breakthrough symptomatic SARS-CoV-2 infections by vaccine

Allele-specific RT-qPCR assay to identify SARS-CoV-2 Omicron variant in wastewater

Coinfection of SARS-CoV-2 and human rhinovirus associated with more severe health outcomes

Assessing the clinical severity of the SARS-CoV-2 Omicron variant

More breakthrough infections but less severe COVID-19 with Omicron

Study confirms coronavirus RNA synthesis occurs inside membrane-bound compartments

Role of novel SARS-CoV-2-derived svRNAs and the involvement of tRF in COVID-19

Sensor based on quantum effects may offer faster and accurate detection of SARS-CoV-2 virus

Comparison of SARS-CoV-2 rapid antigen tests

Comparison of point-of-care SARS-CoV-2 diagnostic kits

What are the long-term effects of COVID-19 on mental health?

Diagnostic assays that use the 2019-nCoV-N1 primer-probe are unlikely to be impacted by Omicron variant

Effect of T cell reactivity in COVID-19 infection and vaccination

Risk of hospitalization for infants and children with COVID-19 below 1%

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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