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Early therapy for preschool depression shows long lasting benefits

Depression affects 1%-2% of children younger than 13 in the U.S. and can arise as early as age 3, but a specialized therapeutic intervention can help preschool-aged children find relief from this condition - with benefits lasting at least four years, according to a new study led by researchers at Washington University School of Medicine in St. Louis.

27 Jun 2025

Targeting mitochondrial dynamics to combat breast cancer metastasis

Breast cancer, particularly triple-negative breast cancer (TNBC), remains a leading cause of cancer-related mortality due to its aggressive nature and limited therapeutic targets.

27 Jun 2025

PIEZO2 ion channel plays critical role in the formation of coronary vessels and the heart

The ion channel PIEZO2 doesn't just convey touch stimuli. It also plays a key role in the development of coronary vessels, a team led by Annette Hammes from the Max Delbrück Center reports in "Nature Cardiovascular Research."

27 Jun 2025

Proteome imbalance from aneuploidy linked to mitochondrial dysfunction

It has been known for several years that abnormal chromosome numbers lead to protein imbalances in the affected cells. Researchers at RPTU have now investigated the detailed effects of such imbalances.

27 Jun 2025

New enzyme can be "turned off" to restore cholesterol balance and reduce inflammation

Scientists at The University of Texas at Arlington have identified a new enzyme that can be "turned off" to help the body maintain healthy cholesterol levels-a significant development that could lead to new treatments for diseases that affect millions of Americans.

27 Jun 2025

Investigating the role of ultra-processed foods in the inheritance of autism and ADHD

In a recent publication released by PubMed, American scientist Dr. Renee Dufault at the Food Ingredient and Health Research Institute, provides a peer-reviewed protocol for determining the role ultra-processed foods play in prenatal heavy metal exposures and changes in the expression of the zinc dependent MT-1 (metallothionein) gene that impact child neurodevelopment.

27 Jun 2025

Pesticides found to disrupt specific gut bacteria linked to inflammation

While emerging evidence suggests pesticides can be toxic to the mix of microorganisms in the digestive system, a new study is the first to map changes to specific gut bacteria based on interactions between human microbes and insect-killing chemicals observed in the lab and an animal model.

27 Jun 2025

Exploring neural responses to mental exhaustion in healthy adults

In experiments with healthy volunteers undergoing functional MRI imaging, scientists have found increased activity in two areas of the brain that work together to react to, and possibly regulate, the brain when it's "feeling" tired and either quits or continues exerting mental effort.

27 Jun 2025

Do spicy foods help or hurt your gut health?

Capsaicin, the spicy compound in chili peppers, not only influences inflammation, metabolism, and cancer risk but also shapes the gut microbiome in complex, context-dependent ways. This comprehensive review highlights both the therapeutic promise and potential risks of capsaicin, calling for deeper research into its microbiome-mediated effects.

26 Jun 2025

Is plastic packaging putting more than just food on your plate?

Researchers systematically mapped the evidence on micro-, meso-, and nanoplastics migrating from plastic food-contact articles (FCAs) into food. While most studies report migration, only a small number provide highly reliable proof linking typical FCA use to MNP presence in food.

26 Jun 2025

Poor diet quality weakens resilience and mental health in food insecure populations

According to the U.S. Department of Agriculture, 13.5% of American households experienced food insecurity at some time during 2023. That means 18 million families didn't have enough to meet their needs and often didn't know where the next meal would come from.

26 Jun 2025

Can saffron treat Alzheimer’s and depression?

Saffron shows promise as a natural treatment for depression and cognitive decline, performing as well as standard drugs in clinical trials. However, more rigorous studies are needed before saffron can be recommended in mainstream psychiatric and dementia care.

26 Jun 2025

New insights into programmed cell death could offer relief for inflammatory bowel disease

New basic science insights into programmed cell death could offer relief for inflammatory bowel disease.

26 Jun 2025

Study shows the correlation between stressed parents and self-harming in adolescents

One in ten Norwegian adolescents has engaged in deliberate self-harm without intending to commit suicide.

26 Jun 2025

Teaching emotional skills improves student wellbeing in Japan

Today, high school students worldwide face unprecedented levels of stress as they navigate academic pressures, issues with social identity, and future career decisions.

26 Jun 2025

Ribonucleases revealed as key players in Mendelian disorders

A new review brings to light the pivotal role of ribonucleases (RNases) in shaping the molecular foundation of Mendelian disorders.

26 Jun 2025

Living in disadvantaged neighborhoods linked to Alzheimer’s biomarkers

People living in more disadvantaged neighborhoods may be more likely to have biomarkers for inflammation and Alzheimer's disease, according to a study published June 25, 2025, in Neurology, the medical journal of the American Academy of Neurology.

26 Jun 2025

Study shows polar winter challenges men’s muscle mass but not hormone levels

Researchers tracked testosterone, cortisol, and body composition in 23 men overwintering at Concordia Station, Antarctica. Despite extreme polar conditions, hormone levels remained stable, though nearly half the crew experienced significant muscle loss.

26 Jun 2025