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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

New SARS-CoV-2 variant JN.1 shows increased transmissibility and immune resistance

A Japanese study published in BioRxiv explores the virological characteristics of the SARS-CoV-2 JN.1 variant, finding it has a higher effective reproductive number and stronger resistance to immunity from other variants, potentially due to the L455S spike protein mutation.

11 Dec 2023

MIT scientists develop nanoparticles to reduce inflammation in the brain

Some Covid-19 vaccines safely and effectively used lipid nanoparticles (LNPs) to deliver messenger RNA to cells. A new MIT study shows that different nanoparticles could be used for a potential Alzheimer's disease (AD) therapy.

11 Dec 2023

Study could pave the way for synergistic therapeutic combinations to better treat SF3B1-mutant MDS

A new study from researchers with Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborating organizations provides insight into the underlying mechanisms of gene mutations commonly seen in patients with myelodysplastic syndromes (MDS) and other myeloid neoplasms.

11 Dec 2023

Study identifies targetable fusion RNAs in breast cancer

Comprehensive profiling of fusion RNAs present in a large cohort of metastatic breast tumors revealed unique fusion mutations that may be therapeutically targetable, according to results presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.

8 Dec 2023

Study unlock secrets of Zika virus's multipurpose enzyme and reveals therapeutic vulnerability

Viruses have limited genetic material - and few proteins - so all the pieces must work extra hard. Zika is a great example; the virus only produces 10 proteins.

8 Dec 2023

Study sheds light on the molecular workings at play when oxygen exceeds normal levels

It only takes holding your breath for slightly too long to understand that too little oxygen is bad for you. But can you also have too much? Indeed, breathing air with a higher oxygen level than your body needs can cause health problems or even death.

8 Dec 2023

Researchers discover next-gen lipid nanoparticles for muscle-focused mRNA delivery

A team of researchers based at the University of Toronto's (U of T) Leslie Dan Faculty of Pharmacy has discovered a novel ionizable lipid nanoparticle that enables muscle-focused mRNA delivery while minimizing off-target delivery to other tissues.

8 Dec 2023

Fused pancreatic cancer organoid system captures tumor heterogeneity and drug resistance

Pancreatic ductal adenocarcinoma (PDAC), that arises from pancreatic epithelial cells, is the most common form of pancreatic cancer, with a very high mortality rate.

7 Dec 2023

Is your body out of sync? Study finds organs age at varying rates

Research uncovers that human organs age at varying rates, with some showing accelerated aging compared to chronological age, significantly impacting overall health and disease risk. The study used advanced blood plasma proteomics to analyze organ-specific aging in nearly 5,700 adults, linking it to increased risks of heart failure and Alzheimer's disease.

7 Dec 2023

Breakthrough discovery paves the way for new methods to detect and treat leukemia

Researchers led by François Fuks - Laboratory of Cancer Epigenetics, ULB Faculty of Medicine, ULB Cancer Research Center and Jules Bordet Institute, H.U.B. - have made a major breakthrough in the understanding and treatment of leukemia.

7 Dec 2023

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

Researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into mRNAs affects ribosomal frameshifting and the overall fidelity of mRNA translation.

7 Dec 2023

From LED screens to genes: The effects of blue light on aging and m6A methylation in fruit flies

Researchers created Drosophila models using multi-omics profiles to elucidate the biological mechanisms and effects of everyday low-intensity blue light exposure (BLE).

7 Dec 2023

New genetic links to coronary artery calcification uncovered, offering treatment insights

A study in Nature Cardiovascular Research identifies two new genetic loci associated with coronary artery calcification (CAC), a key indicator of atherosclerosis and coronary artery disease.

5 Dec 2023

Placental microparticles and their potential to predict and prevent neurodevelopmental disorders

For 30 years, Cheryl Rosenfeld has studied how biological information gets transferred from mothers to babies during pregnancy.

5 Dec 2023

Targeting Alzheimer's with cell-specific genetics

Developing treatments for Alzheimer's disease (AD) is difficult because complex underlying mechanisms drive different types of cells that may contribute to the disorder.

5 Dec 2023

Fruit fly study highlights potential risks of cumulative blue light exposure

In a study on fruit flies, daily low-intensity blue light exposure (BLE), similar to that experienced daily by billions of humans in the form of LED lighting and device screens, changed flies at the sub-cellular level, affecting processes related to aging and circadian rhythms.

5 Dec 2023

Organoid model unveils secrets of the brain's dopaminergic system

A new organoid model of the dopaminergic system sheds lights on its intricate functionality and potential implications for Parkinson's disease.

5 Dec 2023

The past, present and future of automation and digitalization in the life sciences laboratory

In this interview, News-Medical talks to Dr. Klaus Lun and Chris Mason about the past, present and future of automation and digitalization in the life sciences laboratory and especially the impact this could have on next-generation sequencing and genomics.

From Tecan 5 Dec 2023

Arxspan BioDrive: A Versatile Solution for Molecular Biology

In this interview, NewsMedical speaks to SciY about its new all-in-one solution for molecular biology.

From SciY 5 Dec 2023

Scientists unmask molecule that fuels leukemia growth

In a study published in the journal Genes & Diseases, researchers from Beckman Research Institute of City of Hope, explored the impact of m6A modification on the maturation process of precursor microRNAs (pre-miRNAs) and its potential role in tumorigenesis.

4 Dec 2023

RNA News and Research

Further Reading

New SARS-CoV-2 variant JN.1 shows increased transmissibility and immune resistance

MIT scientists develop nanoparticles to reduce inflammation in the brain

Study could pave the way for synergistic therapeutic combinations to better treat SF3B1-mutant MDS

Study identifies targetable fusion RNAs in breast cancer

Study unlock secrets of Zika virus's multipurpose enzyme and reveals therapeutic vulnerability

Study sheds light on the molecular workings at play when oxygen exceeds normal levels

Researchers discover next-gen lipid nanoparticles for muscle-focused mRNA delivery

Fused pancreatic cancer organoid system captures tumor heterogeneity and drug resistance

Is your body out of sync? Study finds organs age at varying rates

Breakthrough discovery paves the way for new methods to detect and treat leukemia

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

From LED screens to genes: The effects of blue light on aging and m6A methylation in fruit flies

New genetic links to coronary artery calcification uncovered, offering treatment insights

Placental microparticles and their potential to predict and prevent neurodevelopmental disorders

Targeting Alzheimer's with cell-specific genetics

Fruit fly study highlights potential risks of cumulative blue light exposure

Organoid model unveils secrets of the brain's dopaminergic system

The past, present and future of automation and digitalization in the life sciences laboratory

Arxspan BioDrive: A Versatile Solution for Molecular Biology

Scientists unmask molecule that fuels leukemia growth

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