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Novel compounds show promise in fighting COVID-19

New research from The Wistar Institute's Salvino lab - led by professor Joseph Salvino, Ph.D. - has identified a novel series of SARS-CoV-2 Mpro inhibitors that may lead to potential new COVID-19 treatments that, according to preclinical testing, effectively inhibits COVID-19 and synergizes with existing anti-COVID therapies.

8 Oct 2024

Policy change linked to rise in treatment-resistant vaginal thrush

A change in policy may be helping to drive a rise in treatment-resistant vaginal thrush, amid significant yearly increases in the prevalence of fungal infections caused by fungal Candida species, suggests the first study of its kind, published online in the journal Sexually Transmitted Infections.

8 Oct 2024

Clonal competition assays reveal tumor cell resistance mechanisms

All cells within the same cancer are not the same. They all have genetic errors that turn them into tumor cells, but these errors are not identical.

8 Oct 2024

Incorrect arm positioning inflates blood pressure readings, risking misdiagnosis

Incorrect arm positioning during blood pressure measurement can overestimate readings, potentially leading to misdiagnosis and overtreatment of hypertension. Proper arm support is essential for accuracy.

8 Oct 2024

Breakthrough study reveals Entropic Pulling mechanism of Hsp70 chaperones

Proteins control most of the body's functions, and their malfunction can have severe consequences, such as neurodegenerative diseases or cancer.

8 Oct 2024

Late-life smoking cessation can significantly extend life expectancy

Quitting smoking even as late as at 75 years of age can meaningfully increase a person's life expectancy, according to a new study in the American Journal of Preventive Medicine, published by Elsevier.

8 Oct 2024

Study identifies RNA molecule crucial for skin wound healing

A new study from Karolinska Institutet in Sweden and the Chinese Academy of Medical Sciences has identified an RNA molecule that is important for skin wound healing.

8 Oct 2024

New insights into how stress affects pancreatic cells and diabetes risk

The cells in your pancreas, like people, can only handle so much stress before they start to break down. Certain stressors, such as inflammation and high blood sugar, contribute to the development of type 2 diabetes by overwhelming these cells.

8 Oct 2024

Maintaining healthy weight may support brain vascular health in aging population

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 18 on September 18, 2024, entitled, "Determinants of cerebral blood flow and arterial transit time in healthy older adults."

8 Oct 2024

Concerns rise over increased industry sponsorship in cancer clinical trials

A growing reliance on industry-sponsored cancer clinical trials in the United States is a reason for concern, say researchers from the UNC Lineberger Comprehensive Cancer Center.

8 Oct 2024

Liver X receptor beta offers new hope in treating depression and anxiety

Liver X receptor beta (LXRβ) shows potential in reducing depression and anxiety by improving neurogenesis, reducing neuroinflammation, and enhancing cognitive and emotional function. More research on LXR agonists could reveal new treatments for mental health disorders.

8 Oct 2024

Placental changes may increase the risk of asthma and allergies in children

Changes in the placenta may increase the risk of children developing asthma and allergies, as shown in new research from örebro University.

8 Oct 2024

Study reveals how morphogens and cell adhesion create sharp tissue boundaries

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, demonstrate how morphogens combined with cell adhesion can generate tissue domains with a sharp boundary in an in vitro model system.

8 Oct 2024

Survey: Most Americans skeptical about weight-loss injections

A new national survey shows that, despite intense marketing, most Americans do not want the new weight-loss injectables, such as Wegovy and Ozempic.

8 Oct 2024

New smartphone apps empower blind users to navigate indoor spaces

Two new apps will enable blind people to navigate indoor buildings with spoken directions from a smartphone app, providing a safe method of wayfinding where GPS doesn't work.

8 Oct 2024

New EU project aims to enhance pandemic preparedness

Covid-19 came like a bolt from the blue. The health, social and economic repercussions of this pandemic event have been considerable and, four years on, we are still suffering from them.

8 Oct 2024

Study reveals marketing tactics of tobacco-free nicotine pouches in the UK

White nicotine pouches that taste like strawberries, are good for your health and evoke a sense of freedom - are as free as only Swedes can be.

8 Oct 2024

Heat stress impacts development of babies during critical early years

Exposure to high levels of heat may both impact the growth of fetuses during pregnancy and infants up to the age of two, a new analysis suggests.

8 Oct 2024

Global analysis reveals disparities in access to new cancer drugs

Despite considerable progress in the discovery and development of new cancer drugs, there are significant disparities in both the availability and timeliness of these medicines worldwide, with poorer countries missing out, suggests a global analysis of new drug launches between 1990 and 2022, published in the open access journal BMJ Global Health.

8 Oct 2024

$Longer waits in emergency care impact outcomes for hip fracture patients, study shows$

Longer waits in emergency care impact outcomes for hip fracture patients, study shows

Waiting more than 4 hours in emergency care for treatment is linked to heightened risks of death and a longer hospital stay for hip fracture patients, reveals a single centre study, published online in Emergency Medicine Journal.

8 Oct 2024