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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Study reveals how maternal diabetes affects birth defects at the single-cell level

The mechanisms by which maternal diabetes mellitus contributes to congenital abnormalities in the fetus.

4 Dec 2023

New drug combination may improve treatment for rare nerve sheath tumors

Combining a pair of experimental drugs may help treat malignant peripheral nerve sheath tumors with fewer harmful side effects, according to preliminary animal studies led by investigators at the Johns Hopkins Kimmel Cancer Center and Johns Hopkins Drug Discovery.

1 Dec 2023

Breakthrough in Malaria detection: new FREM platform delivers 98% accuracy for rapid screening and genotyping

The Flexible, Robust, Equipment-free Microfluidic (FREM) platform for malaria screening and Plasmodium species genotyping.

1 Dec 2023

Study shows how aging affects communication between skin cells

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 22, entitled, "Chronological aging impacts abundance, function and microRNA content of extracellular vesicles produced by human epidermal keratinocytes."

30 Nov 2023

Silencing galectin 1 protein shrinks liver cancer tumors in mice

Researchers at UC Davis Comprehensive Cancer Center have shown that inhibiting a specific protein using gene therapy can shrink hepatocellular carcinoma (HCC) in mice.

30 Nov 2023

New study provides convincing evidence of the essential role of cylicins in sperm development and fertility

Researchers investigated the Role of Cylicins in Spermiogenesis and Male Fertility in Mice and Humans through Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/ CRISPR-associated protein 9 (Cas9) Gene Editing.

30 Nov 2023

Non-invasive monitoring of glucose and adenosine monophosphate biomarkers in saliva

Blood tests are a common, yet often painful, step in health care. But what if we could skip the needles altogether? Saliva and blood contain many of the same biomarkers, and collecting spit is as simple as drooling into a container.

29 Nov 2023

Decoding anxiety: Study reveals brain's role in behavioral inhibition risks

Researchers in the U.S. used non-human primate models to explore the molecular mechanisms and neural systems behind behavioral inhibition, a key risk factor for anxiety disorders. The study identified molecular systems in the posterior orbitofrontal cortex linked to variations in anxious temperament, offering potential targets for treating anxiety disorders.

28 Nov 2023

Abnormal myelin, not loss of myelin, may drive axon degeneration in myelin diseases

Myelin is an insulating sheath around axons - the processes connecting nerve cells - that is mostly composed of lipids and proteins.

28 Nov 2023

Researchers discover new gene targets for precision oncology in esophageal cancer

Researchers have identified a new way to screen genes that cause several different types of cancers to grow, identifying particularly promising targets for precision oncology in oral and esophageal squamous cancers.

28 Nov 2023

Study identifies how three novel genes cause neurodevelopmental disorders

An international study group led by researchers of Children's Hospital of Philadelphia (CHOP) have identified how three novel genes cause neurodevelopmental disorders.

28 Nov 2023

Machine learning program provides more accurate understanding of peptide sequences in cells

Machine learning is now helping researchers analyze the makeup of unfamiliar cells, which could lead to more personalized medicine in the treatment of cancer and other serious diseases.

28 Nov 2023

BioEcho Life Sciences enters the US diagnostic market with an FDA-listed product

The EchoLUTION Viral RNA/DNA Kit is now available for the US diagnosis market to extract nucleic acids from viral particles with a single-step centrifugation technology, reducing processing time for in vitro diagnostic analysis.

From BioEcho Life Sciences GmbH 28 Nov 2023

RNA-based therapy shows promise for treating leukemia in animal models

Each year, about 13,000 people in Deutschland are diagnosed with leukemia, an umbrella term that encompasses various forms of blood cancer.

27 Nov 2023

Genetic mutation in OXR1 gene linked to brain development issues

Study investigates the effects of a loss-of-function mutation in the OXR1 gene on neurodevelopment and cellular functions in the human brain. The research shows that OXR1 deficiency impairs neural differentiation, increases sensitivity to oxidative stress, and alters histone methylation, impacting brain development and potentially contributing to neurological disorders.

27 Nov 2023

Synthetic biologists develop versatile platform for targeted drug delivery

In recent years, cell and gene therapies have shown significant promise for treating cancer, cystic fibrosis, diabetes, heart disease, HIV/AIDS and other difficult-to-treat diseases.

27 Nov 2023

Study uncovers a previously unknown molecular pathway to halt lung cancer

A new study by Tulane University has uncovered a previously unknown molecular pathway that could be instrumental to halting lung cancer in its tracks.

27 Nov 2023

Fiber-free diet key to treating childhood Crohn's disease, new study finds

Research reveals how a fiber-free diet in Exclusive Enteral Nutrition (EEN) helps treat Crohn's disease in children by affecting the intestinal pathobiont Mucispirillum schaedleri. It shows that this diet alters gut microbiota, reducing Mucispirillum's pathogenicity and aiding in managing colitis.

26 Nov 2023

New insights into how SARS-CoV-2 evades our immune system

This review in Cellular and Molecular Immunology delves into the innate immune response to SARS-CoV-2, exploring how the virus evades immunity and the potential role of innate immunity in long-COVID and vaccine responses, shedding light on future therapeutic strategies.

23 Nov 2023

Study demonstrates prolonged persistence of enteroviruses on commonly encountered surfaces

Hand, foot, and mouth disease (HFMD) is a contagious disease that mainly affects young children in the Asia-Pacific region.

23 Nov 2023

RNA News and Research

Further Reading

Study reveals how maternal diabetes affects birth defects at the single-cell level

New drug combination may improve treatment for rare nerve sheath tumors

Breakthrough in Malaria detection: new FREM platform delivers 98% accuracy for rapid screening and genotyping

Study shows how aging affects communication between skin cells

Silencing galectin 1 protein shrinks liver cancer tumors in mice

New study provides convincing evidence of the essential role of cylicins in sperm development and fertility

Non-invasive monitoring of glucose and adenosine monophosphate biomarkers in saliva

Decoding anxiety: Study reveals brain's role in behavioral inhibition risks

Abnormal myelin, not loss of myelin, may drive axon degeneration in myelin diseases

Researchers discover new gene targets for precision oncology in esophageal cancer

Study identifies how three novel genes cause neurodevelopmental disorders

Machine learning program provides more accurate understanding of peptide sequences in cells

BioEcho Life Sciences enters the US diagnostic market with an FDA-listed product

RNA-based therapy shows promise for treating leukemia in animal models

Genetic mutation in OXR1 gene linked to brain development issues

Synthetic biologists develop versatile platform for targeted drug delivery

Study uncovers a previously unknown molecular pathway to halt lung cancer

Fiber-free diet key to treating childhood Crohn's disease, new study finds

New insights into how SARS-CoV-2 evades our immune system

Study demonstrates prolonged persistence of enteroviruses on commonly encountered surfaces

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