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More than 1,000 small changes in DNA identified that influence age of first period

Researchers examined nearly 800,000 women's DNA to explore puberty timing complexities. They identified signals related to menarche timing and investigated their influence on puberty onset.

4 Jul 2024

Scientists unveil KLF15 transcription factor's role in white fat cells, opening new paths for obesity therapy

Researchers found that KLF15 is crucial for maintaining white adipocyte properties in subcutaneous fat, and its deletion induces beige adipocyte characteristics, suggesting new obesity treatment pathways.

4 Jul 2024

Single-cell profiling of lateral septum neurons reveals LSEsr1's role in METH addiction

Recently, a research team led by Dr. ZHU Yingjie from the Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences has published a study in Neuron, the study presents a comprehensive transcriptional profile of the lateral septum (LS) at the single-cell level, elucidating the spatial distribution of its major neuronal types.

3 Jul 2024

Researchers identify potential drugs that make naloxone more potent and longer lasting

The ongoing opioid epidemic in the U.S. kills tens of thousands of people every year. Naloxone, sold under the brand name Narcan, has saved countless lives by reversing opioid overdoses.

3 Jul 2024

Exercise boosts tumor-killing white blood cells in breast cancer patients

A new Finnish study from University of Turku shows that already a 30-minute exercise can increase the proportion of tumor-killing white blood cells in the bloodstream of breast cancer patients.

3 Jul 2024

White blood cell type identified as important contributor to inflammation in obesity

Researchers explored neutrophil involvement in visceral adipose tissue (VAT) inflammation in obesity.

3 Jul 2024

New hope for solid tumors with enhanced CAR-T cells

A promising therapy that treats blood cancers by harnessing the power of the immune system to target and destroy cancer cells could now treat solid tumors more efficiently. Thanks to a recent study published in Molecular Therapy – Methods & Clinical Development from Dan Cappabianca and Krishanu Saha at the Wisconsin Institute for Discovery, Chimeric Antigen Receptor (CAR) T-cell therapy can be improved by altering the conditions the T cells are grown in. And it was all discovered by chance.

3 Jul 2024

Gene discovery points to oxytocin for depression

While investigating two boys from different families with severe obesity, anxiety, autism, and behavioural problems triggered by sounds or smells, a team led by scientists at the University of Cambridge, UK, and Baylor College of Medicine, Houston, USA, discovered that the boys were missing a single gene, known as TRPC5, which sits on the X chromosome.

3 Jul 2024

TRPC5 gene identified as a diagnostic marker of obesity and postpartum depression

Researchers at Baylor College of Medicine, the University of Cambridge and collaborating institutions have discovered that alterations in the human gene TRPC5 cause obesity and postpartum depression.

2 Jul 2024

Advancements in immunotherapy for hepatocellular carcinoma offer hope to patients

Hepatocellular carcinoma (HCC) is a primary liver cancer predominantly arising from chronic liver diseases such as hepatitis B and C infections, alcohol abuse, and metabolic disorders.

2 Jul 2024

Fibrinogen-like protein 1 plays dual role in liver regeneration and hepatocellular carcinoma recurrence

Hepatocellular carcinoma (HCC), a leading cause of cancer-related mortality globally, exhibits a dismal five-year survival rate of only 18%.

2 Jul 2024

New host factors identified as important for SARS-CoV-2 infection

A research team led by Prof. Guo Yusong, Associate Professor of the Division of Life Science at the Hong Kong University of Science and Technology (HKUST), recently made a novel discovery related to the coronavirus (SARS-CoV-2) that causes COVID-19.

2 Jul 2024

Study finds genetic links between childhood weight gain and early puberty

Genes can indirectly influence the age at which girls have their first period by accelerating weight gain in childhood, a known risk factor for early puberty, a Cambridge-led study has found.

1 Jul 2024

Suppressing a protein turns ordinary fat into a calorie burner, study shows

New UCSF study shows that suppressing a protein turns ordinary fat into a calorie burner and may explain why drug trials attempting the feat haven't been successful.

1 Jul 2024

New study reveals key to more effective antihistamines

Even if two molecules have the exact same chemical formula and the same number and types of bonds, their three-dimensional arrangements can still be different.

1 Jul 2024

Study uncovers the role of mGluR1 in pruning early neural connections

Not everything in the brain is meant to last. As our brains assemble, trillions of neural connections have to be built or torn down at the right time and place.

1 Jul 2024

Research paves way for new forms of immunotherapy to treat people with Merkel cell cancer

Scientists behind a new type of immunotherapy are demonstrating significant effects in laboratory experiments in cell samples from patients with the aggressive form of skin cancer, Merkel cell carcinoma.

1 Jul 2024

Study finds specific gut microbiota signature is associated with vulnerability to food addiction

Researchers of a recent study published in Gut explored gut microbial involvement in food addiction-related processes.

1 Jul 2024

Regulatory T cells exist as large, mobile population that travels through body to repair damaged tissue

Researchers investigated populations of regulatory T cells, a type of white blood cell, in various tissues.

1 Jul 2024

Serotonin 2C receptor in the brain regulates memory in people and animal models, research shows

Researchers at Baylor College of Medicine, the University of Cambridge in the U.K. and collaborating institutions have shown that serotonin 2C receptor in the brain regulates memory in people and animal models.

28 Jun 2024

Receptor News and Research

More than 1,000 small changes in DNA identified that influence age of first period

Scientists unveil KLF15 transcription factor's role in white fat cells, opening new paths for obesity therapy

Single-cell profiling of lateral septum neurons reveals LSEsr1's role in METH addiction

Researchers identify potential drugs that make naloxone more potent and longer lasting

Exercise boosts tumor-killing white blood cells in breast cancer patients

White blood cell type identified as important contributor to inflammation in obesity

New hope for solid tumors with enhanced CAR-T cells

Gene discovery points to oxytocin for depression

TRPC5 gene identified as a diagnostic marker of obesity and postpartum depression

Advancements in immunotherapy for hepatocellular carcinoma offer hope to patients

Fibrinogen-like protein 1 plays dual role in liver regeneration and hepatocellular carcinoma recurrence

New host factors identified as important for SARS-CoV-2 infection

Study finds genetic links between childhood weight gain and early puberty

Suppressing a protein turns ordinary fat into a calorie burner, study shows

New study reveals key to more effective antihistamines

Study uncovers the role of mGluR1 in pruning early neural connections

Research paves way for new forms of immunotherapy to treat people with Merkel cell cancer

Study finds specific gut microbiota signature is associated with vulnerability to food addiction

Regulatory T cells exist as large, mobile population that travels through body to repair damaged tissue

Serotonin 2C receptor in the brain regulates memory in people and animal models, research shows

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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