Clinical Trial News and Research

RSS

New clinical trial to test different strengths of a vaccine designed to fight avian influenza

The Duke study is part of a multicenter trial that will test a modified form of an investigational bird flu vaccine to determine whether the vaccine still triggers a strong immune response at lower doses.

4 Apr 2006

Proteomics yields new drug targets for treating cardiogenic shock

When it comes to cell signaling and bioregulation, it's tough to find a more important molecule than nitric oxide (NO). Dysfunction of NO-mediated signaling is thought to be a culprit in lethal cardiovascular conditions such as angina, and septic, cardiogenic and hemorrhagic shock; it may play a role in many other illnesses as well.

3 Apr 2006

GlaxoSmithKline announces start of clinical trials to test two pandemic vaccines against the H5N1

GlaxoSmithKline has announced the start of an international clinical trial program to test two pandemic vaccines against the H5N1 strain of the avian influenza virus in humans. This dual approach reflects the company's commitment to provide health authorities with concrete options to face the threat of a pandemic.

30 Mar 2006

Call to speed access to innovative advances for all breast cancer patients

Breast cancer specialists and advocates at the 5th European Breast Cancer Conference (EBCC-5) called for patients to have equal and speedy access to new breast cancer treatments and procedures, as soon as they are validated by comparative clinical trials.

28 Mar 2006

Treatment of uterine (endometrial) cancer by laparoscopy gives better patient quality of life

Laparoscopy proves safe, reduces hospital stay, and results in improved quality of life.

27 Mar 2006

Gene therapy treatment for brain tumours and infections

In a study published in the March 15 issue of The Journal of Immunology, researchers at Board of Governors' Gene Therapeutics Research Institute at Cedars-Sinai Medical Center have developed a way to overcome immune privilege in the brain to eradicate potentially deadly brain tumors such as glioblastoma multiforme and other types of brain infections.

27 Mar 2006

First human implant of new style Australian artificial heart

On 22 March 2006, a 48 year old male patient suffering NYHA Class IV Heart Failure became the first recipient of HeartWare's HVAD mechanical circulatory assist device.

27 Mar 2006

Grape seed extract appears to lower blood pressure

Grape seed extract lowered the blood pressure of patients who participated in a UC Davis study of the benefits of the supplement on people with high blood pressure.

27 Mar 2006

Trial of paclitaxel with or without bevacizumab as first-line therapy for locally recurrent or metastatic breast cancer

Results from a large, randomised clinical trial for patients with breast cancer show that those who received bevacizumab (Avastin.) in combination with paclitaxel (Taxol.) survived without the disease getting worse for almost twice as long as patients who received paclitaxel alone.

23 Mar 2006

Children whose mothers are depressed are more likely to suffer from anxiety

...mental-health problems and disruptive behavior than those whose moms aren't. And if the mothers don't get better, these kids' problems often become worse, new research shows.

23 Mar 2006

Raloxifene shows potential benefits in treating prostate cancer

In a study to be published in the April, 2006 issue of the British Journal of Urology International, researchers at Cedars-Sinai Medical Center have shown that Raloxifene, a drug commonly used to treat osteoporosis, has a potential clinical benefit in treating men with prostate cancer.

23 Mar 2006

Avicena receives orphan drug designation for Huntington's disease

The Avicena Group has announced today that the United States Food and Drug Administration (FDA) has granted orphan drug designation to HD-02, the company's proprietary drug candidate for the treatment of Huntington's disease.

23 Mar 2006

Inhibiting gamma secretase may prevent amyloid plaque build-up thought to trigger Alzheimer's disease

Oregon Health & Science University is participating in a national study of a drug that may prevent Alzheimer's disease by blocking an enzyme that produces plaques believed to trigger the disorder.

21 Mar 2006

Donepezil (Aricept) helps cognitive function in brain tumor patients after radiation

A drug that is marketed to treat Alzheimer's disease also improves cognitive function, mood and quality of life in brain tumor patients following radiation therapy, according to a research team at Wake Forest University Baptist Medical Center.

21 Mar 2006

Long-term treatment effective in preventing future depressive episodes

People age 70 and older who continued taking the antidepressant that helped them to initially recover from their first episode of depression were 60 percent less likely to experience a new episode of depression over a two-year study period than those who stopped taking the medication

20 Mar 2006

Lives in danger as drug trial goes horribly wrong

In a drug trial which went horribly wrong two men are critically ill in a London hospital and four others are seriously ill, after suffering violent reactions to a new drug they took as part of a clinical trial.

16 Mar 2006

Drug trial goes wrong and six end up intensive care

After taking part in a clinical trial of a new drug six men are now seriously ill in a north London hospital in the UK.

15 Mar 2006

Creative new therapies for atherosclerotic disease

Patients with a build-up of plaque in arteries in the heart, brain and leg face a high risk of major cardiovascular complications.

14 Mar 2006

Valproic acid may help slow the progression of dementia

Researchers have found that a common anticonvulsant drug improved cognitive function and appeared to restore nerve cells in the brains of patients with HIV-related dementia. The results of the Phase I clinical trial are published in the March issue of the scientific journal Neurology.

14 Mar 2006

Study recommends treatment change for pre-leukemia disease

A new study finds that longer courses of a mild form of chemotherapy may help patients with a bone marrow disease only recently considered a form of cancer.

14 Mar 2006