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Study reveals the hidden toll of sudden cardiac death in type 1 and type 2 diabetes

A Danish nationwide study found that people with type 1 and type 2 diabetes have markedly higher rates of sudden cardiac death than the general population, especially at younger ages. At age 30, people with diabetes lose many years of life, with several of those years specifically attributable to sudden cardiac death.

7 Dec 2025

Young Australians are staying on antidepressants for longer than ever

Long-term antidepressant use in Australia increased steadily between 2014 and 2023, with the largest relative rise seen among adolescents and young adults aged 10 to 24 years. Treatment duration also lengthened over time, while apparent dose reduction efforts remained limited, raising concerns about deprescribing practices.

7 Dec 2025

Shingles vaccination is linked to fewer dementia diagnoses and deaths in older adults

A large quasi-experimental study in Wales shows that eligibility for shingles vaccination is linked to fewer new mild cognitive impairment diagnoses and lower dementia-related mortality. Benefits appear strongest in women and are observed at multiple stages of the dementia disease course.

7 Dec 2025

Aza-ven shows superior outcomes compared to induction chemotherapy in AML patients

In a new trial, patients newly diagnosed with acute myeloid leukemia (AML) fared significantly better with a combined regimen of azacitidine and venetoclax compared with conventional induction chemotherapy.

7 Dec 2025

Many families of children with leukemia face significant financial hardship during treatment

Nearly a third of families with children receiving chemotherapy for acute lymphoblastic leukemia (ALL) – the most common pediatric cancer – develop serious financial difficulties during their child's treatment, including losing 25% or more of their household income and struggling to cover the costs of basic living expenses such as housing, food, and utilities.

7 Dec 2025

Intravenous iron shows safe and beneficial outcomes for patients with bacterial infection and anemia

Treatment with intravenous (IV) iron significantly improved survival and increased hemoglobin levels in patients with iron-deficiency anemia who were hospitalized for an acute bacterial infection, according to an analysis of data from more than 85,000 patients.

7 Dec 2025

Most sickle cell patients face long delays for recommended pain relief, study shows

A new study finds that only one in three patients visiting emergency departments (EDs) for severe pain associated with sickle cell disease received appropriate opioid-based pain-relieving medications within the first hour as recommended by the American Society of Hematology (ASH) and National Heart, Lung, and Blood Institute (NHLBI).

6 Dec 2025

Exa-cel shows complete success in early pediatric trials for sickle cell disease and beta-thalassemia

Preliminary results from two trials of the gene therapy exagamglogene autotemcel (exa-cel) suggest the therapy offers an effective cure for beta-thalassemia and sickle cell disease in children younger than 12.

6 Dec 2025

New Lancet case study series highlights how social forces shape patient health

In November, The Lancet, one of the world's most esteemed medical journals, launched a new monthly series of case studies that goes beyond clinical diagnoses to illuminate the social and cultural forces that contribute to each patient's condition.

5 Dec 2025

Protein network locks ABCC4 transporters in place to maintain cyclic AMP signaling levels

When a cell receives a message from outside, it generates a molecule called cyclic AMP (cAMP) to relay this message. To ensure the signal reaches the correct effector without triggering pathways accidentally, cAMP levels must be maintained around their point of origin and at the right level.

5 Dec 2025

New Lancet series blends social science with medicine to tackle global health inequities

Can doctors in California learn from a patient who was bounced from one specialist to another in Japan? Can clinicians in London take lessons from a patient seeking asylum while suffering a medical emergency at the U.S.-Mexico border? Can doctors treating refugees in Africa inform health policy around the world?

5 Dec 2025

Study finds mixed reviews of virtual nursing programs among bedside nurses

Hospitals struggling to attract and retain enough registered nurses at the bedside are implementing alternative strategies to ensure patients get needed nursing care.

5 Dec 2025

Genetic variant linked to higher heart failure risk in children with myocarditis

A genetic variant is likely putting some children suffering with myocarditis - inflammation of the heart muscle - at higher risk of developing heart failure, which can be fatal, according to a study published today in Circulation Heart Failure.

5 Dec 2025

Restrictive state abortion laws may affect frontline care in obstetric emergencies

Although the United States does not guarantee health care as a right, federal law mandates that hospitals cannot deny anyone lifesaving emergency care.

5 Dec 2025

$New targeted alpha therapy shows promise for patients with radioiodine-refractory thyroid cancer$

New targeted alpha therapy shows promise for patients with radioiodine-refractory thyroid cancer

A new targeted alpha therapy is showing promise for patients whose thyroid cancer no longer responds to radioactive iodine, the standard beta-emitting treatment. In a first-in-human study, investigators found that a single dose of the alpha-emitting radionuclide 211At (astatine) was both well-tolerated and effective, achieving disease control without molecularly targeted drugs.

5 Dec 2025

AI model could help radiologists identify brain abnormalities in MRI scans

A new AI model could help radiologists identify brain abnormalities in MRI scans for all conditions including stroke, multiple sclerosis and brain tumors.

5 Dec 2025

Study shines light on how P2X4 receptor can be inhibited

A study carried out by the University of Bonn and the University Hospital Bonn throws light on how an important receptor can be inhibited.

5 Dec 2025

Higher PFAS levels reduce blood sugar improvements after teen bariatric surgery

A new USC study shows teens with higher blood levels of per- and polyfluoroalkyl substances (PFAS) measured before bariatric surgery had smaller improvements in blood sugar over five years, including fasting glucose and hemoglobin A1c (HbA1c), which measures average blood sugar levels over the past 60-90 days.

4 Dec 2025

Study provides first molecular evidence that ferroptosis can drive neurodegeneration

Researchers at Helmholtz Munich, the Technical University of Munich and the LMU University Hospital Munich uncovered a mechanism that protects nerve cells from premature cell death, known as ferroptosis.

4 Dec 2025

Bacterial enzyme linked to heart complications in pneumonia

Pneumonia is a disease that burdens the healthcare system with more that 1.2 million emergency room visits each year and more than 41,000 adult deaths in the United States.

4 Dec 2025

Hospital News and Research

Study reveals the hidden toll of sudden cardiac death in type 1 and type 2 diabetes

Young Australians are staying on antidepressants for longer than ever

Shingles vaccination is linked to fewer dementia diagnoses and deaths in older adults

Aza-ven shows superior outcomes compared to induction chemotherapy in AML patients

Many families of children with leukemia face significant financial hardship during treatment

Intravenous iron shows safe and beneficial outcomes for patients with bacterial infection and anemia

Most sickle cell patients face long delays for recommended pain relief, study shows

Exa-cel shows complete success in early pediatric trials for sickle cell disease and beta-thalassemia

New Lancet case study series highlights how social forces shape patient health

Protein network locks ABCC4 transporters in place to maintain cyclic AMP signaling levels

New Lancet series blends social science with medicine to tackle global health inequities

Study finds mixed reviews of virtual nursing programs among bedside nurses

Genetic variant linked to higher heart failure risk in children with myocarditis

Restrictive state abortion laws may affect frontline care in obstetric emergencies

New targeted alpha therapy shows promise for patients with radioiodine-refractory thyroid cancer

AI model could help radiologists identify brain abnormalities in MRI scans

Study shines light on how P2X4 receptor can be inhibited

Higher PFAS levels reduce blood sugar improvements after teen bariatric surgery

Study provides first molecular evidence that ferroptosis can drive neurodegeneration

Bacterial enzyme linked to heart complications in pneumonia

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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