Nanoparticle News and Research

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In nanotechnology, a particle is defined as a small object that behaves as a whole unit in terms of its transport and properties. It is further classified according to size: in terms of diameter, fine particles cover a range between 100 and 2500 nanometers, while ultrafine particles, on the other hand, are sized between 1 and 100 nanometers.

MRI tracks survival of pancreatic islets after transplantation

Magnetic resonance imaging (MRI) with an approved contrast agent may provide a practical way of monitoring the survival of transplanted pancreatic islets.

12 Sep 2006

Synthetic low-density lipoprotein-like nanoparticles target brain tumors

Low-density lipoprotein, better known as LDL, is one of the chief villains involved in the development of coronary artery disease.

12 Sep 2006

New screening method shows how nanoparticles interact with human cells

Scientists at the Brookhaven National Laboratory have developed a screening method to examine how newly made nanoparticles interact with human cells following exposure for various times and doses. Using this new method, the investigators have been able to visualize how human cells interact with some specific types of carbon nanoparticles.

12 Sep 2006

New information on how to design nanoparticles that avoid macrophage uptake

Few researchers doubt the potential for nanoparticles to revolutionize the way anticancer drugs and imaging agents are delivered to tumors.

12 Sep 2006

Scientists develop magnetic nanoparticles for medicine

Magnetic iron oxide nanoparticles have already proven their utility for imaging metastatic breast cancer lesions in sentinel lymph nodes, and numerous groups are attempting to use iron nanoparticles in other imaging applications.

5 Sep 2006

Targeted nanoparticles to improve Boron-Neutron capture therapy

Boron-neutron capture therapy (BNCT) is an experimental treatment for virulent brain cancer that aims to kill malignant cells by generating high-energy alpha particles inside tumors.

5 Sep 2006

New methods for screening nanoparticles and interaction with human cells

Scientists have developed a screening method to examine how newly made nanoparticles - particles with dimensions on the order of billionths of a meter - interact with human cells following exposure for various times and doses.

21 Aug 2006

Investigation of the proinflammatory potential of biodegradable nanoparticle drug delivery systems in the lung

Drug developers consider the lungs to be an excellent route through which to administer drugs.

21 Aug 2006

Targeted magnetic nanoparticles may be useful in both detecting and treating metastatic breast cancer

An in-depth study of nanoparticle distribution in tumor-bearing mice has shown that targeted magnetic nanoparticles accumulate and cluster in both primary breast tumors and metastatic lesions that have developed in the lung.

21 Aug 2006

St. John's wort and polymeric nanoparticles to treat ovarian tumors using light

By combining a compound produced by the plant St. John's wort with polymeric nanoparticles, researchers at the University of Geneva in Switzerland have developed a promising method for treating ovarian tumors using light.

21 Aug 2006

Heat treatment may zap cancer cells

Scientists believe they have discovered a clue as to why so many men with testicular cancer survive against the odds.

26 Jul 2006

Heat sensitivity may make testicular cancer cells more susceptible to standard treatments and die off more readily

Experts at Johns Hopkins have linked scientific evidence spanning more than 30 years to suggest an explanation for why testicular cancer patients like seven-time Tour de France winner Lance Armstrong survive far better than patients with other advanced cancers.

26 Jul 2006

Herceptin-linked nanoparticles for targeted cancer therapy

Albumin nanoparticles have recently proven their mettle as anticancer agents with the 2005 approval of Abraxane to treat metastatic breast cancer.

17 Jul 2006

Diblock copolymer micellar nanoparticles decorated with annexin-A5 proteins

One of the banes of modern cancer therapy is that clinicians and patients must often wait months before they can tell if a given treatment is working.

17 Jul 2006

Functionalized carbon nanotubes are non-cytotoxic and preserve the functionality of primary immune cells

Various types of carbon-based nanomaterials, such as buckyballs and nanotubes, have shown promise as drug delivery tools and imaging agents, but reports of toxicity associated with some of these materials have raised questions about their ultimate utility in clinical oncology.

10 Jul 2006

Proteolytic activity monitored by fluorescence resonance energy transfer through quantum-dot-peptide conjugates

Using a synthetic peptide modeled after the protein that the human immunodeficiency virus (HIV) uses to enter cells, a multi-institutional research team has created quantum dots that can penetrate the cell membrane and image internal structures in a cell.

10 Jul 2006

Nanoscale metal-organic frameworks as potential multimodal contrast enhancing agents

By combining the properties of inorganic and organic molecules in one material, researchers at the Carolina Center of Cancer Nanotechnology Excellence (CCNE) have developed a new class of nanomaterials that can be used to create multifunctional nanoparticles.

10 Jul 2006

Nanoparticle News and Research

Further Reading

MRI tracks survival of pancreatic islets after transplantation

Synthetic low-density lipoprotein-like nanoparticles target brain tumors

New screening method shows how nanoparticles interact with human cells

New information on how to design nanoparticles that avoid macrophage uptake

Scientists develop magnetic nanoparticles for medicine

Targeted nanoparticles to improve Boron-Neutron capture therapy

New methods for screening nanoparticles and interaction with human cells

Investigation of the proinflammatory potential of biodegradable nanoparticle drug delivery systems in the lung

Targeted magnetic nanoparticles may be useful in both detecting and treating metastatic breast cancer

St. John's wort and polymeric nanoparticles to treat ovarian tumors using light

Heat treatment may zap cancer cells

Heat sensitivity may make testicular cancer cells more susceptible to standard treatments and die off more readily

Herceptin-linked nanoparticles for targeted cancer therapy

Diblock copolymer micellar nanoparticles decorated with annexin-A5 proteins

Functionalized carbon nanotubes are non-cytotoxic and preserve the functionality of primary immune cells

Proteolytic activity monitored by fluorescence resonance energy transfer through quantum-dot-peptide conjugates

Nanoscale metal-organic frameworks as potential multimodal contrast enhancing agents

Imaging pancreatic cancer with a peptide-nanoparticle conjugate targeted to normal pancreas

New polymer-lipid hybrid nanoparticle

Thermosensitive pluronic micelles stabilized by shell cross-linking with gold nanoparticles

A practical guide to lipid nanoparticle formulation and resizing eBook

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Industry Focus eBook - Life Science Microscopy (2nd Edition)

BFEB: Advances in microplate-based assays and analysis

Biologics stability screening toolkit: Three practical workflows for accelerating formulation development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery