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New discovery on mitochondrial protein could transform Charcot-Marie-Tooth treatment

Researchers from Cologne, Bochum, Padova and Angers have discovered a novel connection between mitochondrial function, protein quality control and cellular health, whose failure could be the leading cause in the currently incurable neurological disease Charcot-Marie-Tooth (CMT).

14 Feb 2025

A step toward precision medicine: New drug targets for heart failure

Researchers identify several promising drug targets for heart failure and its clinical subtypes.

14 Feb 2025

Leinco Technologies awarded $1M grant to develop rapid test for intestinal immunity to polio

Leinco Technologies, a leader in antibody and protein development, is thrilled to announce that it has been awarded a $1 M grant from the Gates Foundation.

From Leinco Technologies 14 Feb 2025

Researchers uncover cause of persistent blood clots despite treatment

A team of researchers have made a new discovery in the field of hematology, providing an explanation for spontaneous and unusual blood-clotting that continues to occur despite treatment with full-dose blood thinners.

14 Feb 2025

New insight into gut stem cell aging

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular signal-regulated kinase (ERK)/mitogen-activated protein kinase (MAPK) signaling is essential for preserving the intestinal stem cell population during aging.

13 Feb 2025

Rethinking red meat: Are dietary guidelines missing the bigger picture?

Research highlights the critical role of red meat in providing essential nutrients like iron, zinc, and B12, particularly for vulnerable populations, while questioning the low-certainty evidence linking it to chronic diseases. It urges policymakers to balance health, environmental, and economic factors when considering dietary guidelines.

13 Feb 2025

Online weight management program helps rural residents lose weight

People living in rural areas are at greater risk for obesity than the general population, and they often have limited access to healthy, affordable food, physical activity facilities, public transportation, and health care institutions.

13 Feb 2025

Researchers discover genetic mutation linked to toxic protein buildup in Alzheimer's

The root causes of most forms of Alzheimer's disease largely remain a mystery. Now, researchers have revealed a new piece of the puzzle.

13 Feb 2025

Gut bacteria could one day serve as microscopic in-house pharmacists

Hundreds of different species of microbes live, laugh, and love in your gut. In the future, one of these might serve a new function: microscopic in-house pharmacist.

13 Feb 2025

Protein shuttling mechanism enables bacteria to survive exposure to antibiotics

A Cornell University-led collaboration has uncovered the equipment that enables bacteria to survive exposure to antibiotics: a shuttling mechanism that helps a complex of proteins pump out a wide spectrum of antibiotics along with other physiological substrates from the cell.

13 Feb 2025

Guardian molecule found to prevent cancer cells from changing identity

A guardian molecule ensures that liver cells do not lose their identity. This has been discovered by researchers from the German Cancer Research Center (DKFZ), the Hector Institute für Translational Brain Research (HITBR), and from the European Molecular Biology Laboratory (EMBL).

13 Feb 2025

Olpasiran significantly lowers "bad cholesterol" linked to cardiovascular risk

The RNA inhibitor olpasiran significantly reduces a type of "bad cholesterol" that's associated with a high risk of cardiovascular events, according to results from an analysis by a Mount Sinai researcher of a phase 2 trial.

13 Feb 2025

The growing list of human viruses: Are we prepared for the next outbreak?

Researchers review the ever-growing list of human viruses, examining their diversity, transmission pathways, and the urgent need for prevention and global surveillance.

12 Feb 2025

Study uncovers how MAGE-4 and Pten loss promote aggressive tumor growth

A study published in Science Advances reveals a novel strategy that allows tumors to evade the body's immune response critical for their elimination.

12 Feb 2025

Study identifies vitamin E succinate as key to tumor growth control

High levels of fat mass and obesity-associated protein (FTO) have been linked to increased tumor growth and resistance to immunotherapy.

12 Feb 2025

McMaster University researchers discover new blood clotting disorder

Researchers at McMaster University have made a groundbreaking discovery in the field of hematology, providing an explanation for spontaneous and unusual blood-clotting that continues to occur despite treatment with full-dose blood thinners.

12 Feb 2025

Vascular changes in brain trauma could trigger Alzheimer’s development

An increased risk of dementia among individuals exposed to brain trauma, traumatic brain injury, has been known for almost a century.

12 Feb 2025

EMBL researchers reveal new structural insights into minor spliceosome function

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell select this information? A large molecular machine called the spliceosome continuously separates the coding and non-coding regions of our genes – and it's doing this even as you read these lines.

12 Feb 2025

Inhaled antibody therapy shows promise for COVID-19 treatment

The inhaled monoclonal antibody IN-006 shows promise in COVID-19 treatment, with high airway antibody levels and a favorable safety profile in healthy adults.

12 Feb 2025

Marigold flowers: A potential new superfood

Packed with nutrients, marigolds offer antioxidants, vitamins, and minerals, highlighting their potential as functional foods for enhanced health benefits.

12 Feb 2025