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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Genetic vulnerability of leukemia cells uncovered

Leukemia is the most common type of cancer in children. Treatment involves intensive chemotherapy, which has severe side effects due to its non-specific mode of action.

22 Nov 2023

MaxCyte joins the alliance for mRNA medicines (AMM) as a founding member

MaxCyte, Inc. today announced that it has joined the Alliance for mRNA Medicines, as a founding member.

From MaxCyte, Inc. 22 Nov 2023

Novel urine-based prognostic model promises to transform bladder cancer treatment

In a study published in the journal Genes & Diseases, researchers from Fudan University, have developed a novel urine-based prognostic model that promises to transform the management and treatment of bladder cancer.

21 Nov 2023

Breakthrough in HIV treatment: NMN shows promise in reducing CD4+ T cell activation

The impact of nicotinamide mononucleotide (NMN) on Clusters of differentiation 4+ (CD4+ ) Thymus cells (T cells) viz.

21 Nov 2023

Avian influenza A H5N1 virus impacts wide range of wildlife in the U.S., study shows

Study highlights the spread of the highly pathogenic avian influenza A (H5N1) virus among non-domesticated animals in the U.S., revealing neurological symptoms as a key clinical presentation and expanding the range of species affected by this Eurasian lineage virus.

19 Nov 2023

Pigeon virus causes fatal neurological disease in young leukemia patient

A case report details a fatal neurologic disease in an immunocompromised toddler caused by pigeon avian paramyxovirus, underscoring the effectiveness of metagenomic testing in diagnosing complex infectious diseases.

19 Nov 2023

Novel tool can help with analysis of single cell data

CITE-seq (cellular indexing of transcriptomes and epitopes) is an RNA sequencing-based method that simultaneously quantifies cell surface protein and transcriptomic data within a single cell readout.

17 Nov 2023

Scientists uncover "genomic tug of war" that influences chemotherapy's effectiveness

Some patients with myelodysplastic syndromes, like acute myeloid leukemia, benefit from a chemotherapy drug called decitabine that stunts cancer growth. But many others are resistant to decatibine's effects or become resistant over time.

16 Nov 2023

Gene splicing determines CD20 levels and response to monoclonal antibody therapy

Immunotherapies that target the CD20 antigen have revolutionized how patients with a variety of blood cancers and hematologic disorders have been treated.

16 Nov 2023

Exploring the dual role of nirmatrelvir and bisphosphonates in COVID-19 treatment and immunity

Review examines nirmatrelvir and bisphosphonates in treating COVID-19, revealing their impact on SARS-CoV-2-specific adaptive immunity and potential to mitigate severe infections, highlighting the need for balanced long-term immunity management.

16 Nov 2023

Molecular trap offers hope for ALS treatment

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects neurons in the brain and spinal cord causing loss of muscle control.

16 Nov 2023

MaxCyte joins the Alliance for mRNA Medicines (AMM) as a founding member

MaxCyte, Inc., a leading, cell-engineering focused company providing enabling platform technologies to advance the discovery, development and commercialization of next-generation cell-based therapeutics and innovative bioprocessing applications, today announced that it has joined the Alliance for mRNA Medicines (AMM), as a founding member.

From MaxCyte, Inc. 16 Nov 2023

Curcumin boosts brain delivery of HIV drug, curbing inflammation and oxidative stress

Study shows curcumin enhances antiretroviral delivery and reduces inflammation and oxidative stress in HIV, offering potential improvements in treating HIV-associated neurocognitive disorders.

16 Nov 2023

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Study reveals that senolytics can reduce aging in human brain organoids and mitigate COVID-19 neuropathology, suggesting their potential as a therapeutic strategy against brain aging and coronavirus-related neurological complications.

15 Nov 2023

Bacteria fight phages with RNA-based immune defense

There's no organism on earth that lives free of threat - including bacteria. Predatory viruses known as phages are among their most dire foes, infiltrating their cells to replicate and take over.

15 Nov 2023

RNA-based molecular subtypes can help predict response to chemotherapy in muscle-invasive bladder cancer

RNA-based molecular subtypes modestly improved predictions for pathologic downstaging in muscle-invasive bladder cancer.

15 Nov 2023

Call for global action to utilize genomic surveillance to address antimicrobial resistance

During the COVID-19 pandemic, genomic surveillance proved vital in helping understand the evolution and spread of the SARS-CoV-2 virus.

14 Nov 2023

Study uses cellulose sheets to map body's extracellular vesicles, unlocking disease insights

Study demonstrates the use of cellulose nanofiber sheets for spatial analysis of extracellular vesicles, revealing their geographical heterogeneity in the human body, which could advance the understanding and treatment of diseases.

14 Nov 2023

BU researcher awarded $589,000 grant from the Breast Cancer Research Foundation

Julie Palmer, ScD, co-director of the Boston University-Boston Medical Center (BU-BMC) Cancer Center, has been awarded a one-year, $589,000 Research Grant from the Breast Cancer Research Foundation (BCRF) for her research, "Breast Cancer Drivers in Black Women: Society to Cells."

14 Nov 2023

Novel mechanism of maternal-fetal communication discovered

A research group from the University of Oulu, Finland, has shown that nanoparticles originating from maternal gut bacteria are present in amniotic fluid.

14 Nov 2023

RNA News and Research

Further Reading

Genetic vulnerability of leukemia cells uncovered

MaxCyte joins the alliance for mRNA medicines (AMM) as a founding member

Novel urine-based prognostic model promises to transform bladder cancer treatment

Breakthrough in HIV treatment: NMN shows promise in reducing CD4+ T cell activation

Avian influenza A H5N1 virus impacts wide range of wildlife in the U.S., study shows

Pigeon virus causes fatal neurological disease in young leukemia patient

Novel tool can help with analysis of single cell data

Scientists uncover "genomic tug of war" that influences chemotherapy's effectiveness

Gene splicing determines CD20 levels and response to monoclonal antibody therapy

Exploring the dual role of nirmatrelvir and bisphosphonates in COVID-19 treatment and immunity

Molecular trap offers hope for ALS treatment

MaxCyte joins the Alliance for mRNA Medicines (AMM) as a founding member

Curcumin boosts brain delivery of HIV drug, curbing inflammation and oxidative stress

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Bacteria fight phages with RNA-based immune defense

RNA-based molecular subtypes can help predict response to chemotherapy in muscle-invasive bladder cancer

Call for global action to utilize genomic surveillance to address antimicrobial resistance

Study uses cellulose sheets to map body's extracellular vesicles, unlocking disease insights

BU researcher awarded $589,000 grant from the Breast Cancer Research Foundation

Novel mechanism of maternal-fetal communication discovered

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